Name: KRAS G12D-IN-29
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT220772196
Cas No:3018057-89-8
常用名:KRAS G12D-IN-29
IUPAC:5-[(4R,7S,8S,9S)-17-{[(2R,7aS)-2-fluoro-hexahydro-1H-pyrrolizin-7a-yl]methoxy}-14-fluoro-9-methyl-10-oxa-2,12,16,18,20-pentaazapentacyclo[9.7.1.1^{4,7}.0^{2,8}.0^{15,19}]icosa-1(19),11,13,15,17-pentaen-13-yl]-2-fluoro-3-methyl-4-(trifluoromethyl)aniline
IUPAC:5-[(4R,7S,8S,9S)-17-{[(2R,7aS)-2-fluoro-hexahydro-1H-pyrrolizin-7a-yl]methoxy}-14-fluoro-9-methyl-10-oxa-2,12,16,18,20-pentaazapentacyclo[9.7.1.1^{4,7}.0^{2,8}.0^{15,19}]icosa-1(19),11,13,15,17-pentaen-13-yl]-2-fluoro-3-methyl-4-(trifluoromethyl)aniline
InChI key:InChIKey=HLUXAQFQTFKPSI-WMHAXWKYSA-N

分子式:C31H33F6N7O2
分子量:649.642
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@]12CC[C@]([H])(N1)[C@@]1([H])[C@H](C)Oc3nc(c(F)c4nc(OC[C@@]56CCCN5C[C@H](F)C6)nc(N1C2)c34)-c1cc(N)c(F)c(C)c1C(F)(F)F
SMILES:[H][C@]12CC[C@]([H])(N1)[C@@]1([H])[C@H](C)Oc3nc(c(F)c4nc(OC[C@@]56CCCN5C[C@H](F)C6)nc(N1C2)c34)-c1cc(N)c(F)c(C)c1C(F)(F)F

KRAS G12D inhibitor 29 (Compound Formula (I)) 是一种口服活性和选择性的KRASG12D抑制剂，通过阻断KRASG12D介导的下游信号抑制肿瘤细胞增殖。KRAS G12D inhibitor 29 适用于研究与KRASG12D突变相关的癌症，包括胰腺癌、肺癌、结肠癌。

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~