Name: 5'(E)-VP-2'-OMe-U Phosphoramidite
Rating: 5 (10 reviews)

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结构编辑

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HIT ID:HIT220773208
Cas No:1882067-09-5
常用名:5'(E)-VP-2'-OMe-U Phosphoramidite
常用名:5'(E)-VP-2'-OMe-U Phosphoramidite
IUPAC:[({2-[(2R,3R,4R,5R)-3-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-methoxyoxolan-2-yl]ethenyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl 2,2-dimethylpropanoate
IUPAC:[({2-[(2R,3R,4R,5R)-3-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-methoxyoxolan-2-yl]ethenyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl 2,2-dimethylpropanoate
InChI key:InChIKey=AJJPYIXDIHURAB-CIYDTTPESA-N

分子式:C32H52N4O13P2
分子量:762.731
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](O[C@H]1n1ccc(=O)[nH]c1=O)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C
SMILES:CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](O[C@H]1n1ccc(=O)[nH]c1=O)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C

5'(E)-VP-2'-OMe-U Phosphoramidite 是一种亚磷酰胺，包含5' DMT 和 2'-O-甲基保护的尿苷。5'(E)-VP-2'-OMe-U Phosphoramidite 广泛应用于寡核苷酸的合成。

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