• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT220912067
有库存
HIT220912067
 sdf 文件
结构编辑
类似物检索
HIT220912067
  • HIT ID:HIT220912067
  • Cas No:179756-85-5
  • 常用名:Eptapirone fumarate
  • IUPAC:(2E)-but-2-enedioic acid; 4-methyl-2-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
    IUPAC:(2E)-but-2-enedioic acid; 4-methyl-2-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
  • InChI key:InChIKey=IRTCWPNSLGQHOR-WLHGVMLRSA-N
  • 分子式:C20H27N7O6
  • 分子量:461.479
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:OC(=O)\C=C\C(O)=O.Cn1c(=O)cnn(CCCCN2CCN(CC2)c2ncccn2)c1=O
    SMILES:OC(=O)\C=C\C(O)=O.Cn1c(=O)cnn(CCCCN2CCN(CC2)c2ncccn2)c1=O
  • Eptapirone, also known as F11440, is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone, in exerting 5-HT1A agonist activity at pre- and postsynaptic receptors in rats (measured by, for example, its ability to decrease hippocampal extracellular serotonin (5-HT) levels and to increase plasma corticosterone levels, respectively).
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层