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  3. HIT220913292
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HIT220913292
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HIT220913292
  • HIT ID:HIT220913292
  • Cas No:1356497-92-1
  • 常用名:PT-S58
  • IUPAC:methyl 3-{[4-(tert-butylamino)-2-methoxyphenyl]sulfamoyl}thiophene-2-carboxylate
    IUPAC:methyl 3-{[4-(tert-butylamino)-2-methoxyphenyl]sulfamoyl}thiophene-2-carboxylate
  • InChI key:InChIKey=JSUWAIOZKBYWCJ-UHFFFAOYSA-N
  • 分子式:C17H22N2O5S2
  • 分子量:398.49
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:COC(=O)c1sccc1S(=O)(=O)Nc1ccc(NC(C)(C)C)cc1OC
    SMILES:COC(=O)c1sccc1S(=O)(=O)Nc1ccc(NC(C)(C)C)cc1OC
  • PT-S58 is a PPAR β/δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPARβ/δ. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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