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HIT220913387
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HIT220913387
  • HIT ID:HIT220913387
  • Cas No:1184991-14-7
  • 常用名:Clofibric Acid-d4
  • IUPAC:2-[4-chloro(2,3,5,6-2H4)phenoxy]-2-methylpropanoic acid
    IUPAC:2-[4-chloro(2,3,5,6-2H4)phenoxy]-2-methylpropanoic acid
  • InChI key:InChIKey=TXCGAZHTZHNUAI-LNFUJOGGSA-N
  • 分子式:C10H11ClO3
  • 分子量:218.67
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[2H]c1c([2H])c(OC(C)(C)C(O)=O)c([2H])c([2H])c1Cl
    SMILES:[2H]c1c([2H])c(OC(C)(C)C(O)=O)c([2H])c([2H])c1Cl
  • Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 µg/L. Clofibric acid has been found in wastewater effluent.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 2,370.00
    1

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