• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT220913388
有库存
HIT220913388
 sdf 文件
结构编辑
类似物检索
HIT220913388
  • HIT ID:HIT220913388
  • Cas No:2081940-67-0
  • 常用名:INCB059872 tosylate
  • IUPAC:1-{[4-(methoxymethyl)-4-({[(1R,2S)-2-phenylcyclopropyl]amino}methyl)piperidin-1-yl]methyl}cyclobutane-1-carboxylic acid; 4-methylbenzene-1-sulfonic acid
    IUPAC:1-{[4-(methoxymethyl)-4-({[(1R,2S)-2-phenylcyclopropyl]amino}methyl)piperidin-1-yl]methyl}cyclobutane-1-carboxylic acid; 4-methylbenzene-1-sulfonic acid
  • InChI key:InChIKey=ZOLYYKZGDCMNJM-CMXBXVFLSA-N
  • 分子式:C30H42N2O6S
  • 分子量:558.73
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cc1ccc(cc1)S(O)(=O)=O.COCC1(CN[C@@H]2C[C@H]2c2ccccc2)CCN(CC2(CCC2)C(O)=O)CC1
    SMILES:Cc1ccc(cc1)S(O)(=O)=O.COCC1(CN[C@@H]2C[C@H]2c2ccccc2)CCN(CC2(CCC2)C(O)=O)CC1
  • INCB059872, also known as INCB59872, is a potent, selective, and orally active lysine-specific demethylase 1 inhibitor. INCB059872 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively, through amine oxidation. LSD1 inhibition enhances H3K4 methylation and increases the expression of tumor-suppressor genes. In addition, LSD1 demethylates mono- or di-methylated H3K9 which increases gene expression of tumor promoting genes; inhibition of LSD1 promotes H3K9 methylation and decreases transcription of these genes.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    8-10周
    纯度
    -
    ¥ 13,900.00
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层