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HIT220913443
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HIT220913443
  • HIT ID:HIT220913443
  • Cas No:1287076-43-0
  • 常用名:Albendazole-D7
  • IUPAC:methyl N-{5-[(1,1,2,2,3,3,3-2H7)propylsulfanyl]-1H-1,3-benzodiazol-2-yl}carbamate
    IUPAC:methyl N-{5-[(1,1,2,2,3,3,3-2H7)propylsulfanyl]-1H-1,3-benzodiazol-2-yl}carbamate
  • InChI key:InChIKey=HXHWSAZORRCQMX-JOMZKNQJSA-N
  • 分子式:C12H15N3O2S
  • 分子量:272.37
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])Sc1ccc2[nH]c(NC(=O)OC)nc2c1
    SMILES:[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])Sc1ccc2[nH]c(NC(=O)OC)nc2c1
  • Albendazole-D7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole (<a style="color:#E14C54" href="/compound/albendazole">T1152</a>) is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths,including liver flukes,tapeworms,and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Albendazole (<a style="color:#E14C54" href="/compound/albendazole">T1152</a>) (0.05% in the diet)protects mice against lethal infection with A. suum larvae. It also inhibits growth of HT-29 human colorectal cancer cells (IC50 = 0.12 µM),halts the cell cycle at the G2/M phase,and induces apoptosis. In an HT-29 mouse xenograft model,it inhibits peritoneal tumor growth when administered intraperitoneally at a dose of 150 mg/kg but not when administered orally. Albendazole (<a style="color:#E14C54" href="/compound/albendazole">T1152</a>)inhibits mammalian tubulin polymerization and inhibits binding of [3H]mebendazole t......
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 4,200.00
    1

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