ZL0516 | CAS 2230496-93-0 | AnyMole

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HIT220913556

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HIT220913556

HIT ID:HIT220913556
Cas No:2230496-93-0
常用名:ZL0516
IUPAC:2-{4-[(2R)-2-hydroxy-3-(4-methylpiperazin-1-yl)propoxy]-3,5-dimethylphenyl}-5,7-dimethoxy-4H-chromen-4-one
IUPAC:2-{4-[(2R)-2-hydroxy-3-(4-methylpiperazin-1-yl)propoxy]-3,5-dimethylphenyl}-5,7-dimethoxy-4H-chromen-4-one
InChI key:InChIKey=UDPXIEUTIPNLKC-HXUWFJFHSA-N

分子式:C27H34N2O6
分子量:482.577
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:COc1cc(OC)c2c(c1)oc(cc2=O)-c1cc(C)c(OC[C@H](O)CN2CCN(C)CC2)c(C)c1
SMILES:COc1cc(OC)c2c(c1)oc(cc2=O)-c1cc(C)c(OC[C@H](O)CN2CCN(C)CC2)c(C)c1

ZL0516 is a is a chromone derivatives used as orally bioavailable BRD4-selective inhibitor. This BRD4 BD1 inhibitor has demonstrated impressive in vivo efficacy and overall promising pharmacokinetic properties, indicating its therapeutic potential for the treatment of inflammatory diseases.

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TargetMolSC
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货期
6-8周
纯度
-
¥ 10,600.00
1

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