Name: OSU-53
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT220913563
Cas No:1290069-19-0
常用名:OSU-53
IUPAC:N-(4-{[(5Z)-3-[(1-methylcyclohexyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)-4-nitro-3-(trifluoromethyl)benzene-1-sulfonamide
IUPAC:N-(4-{[(5Z)-3-[(1-methylcyclohexyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)-4-nitro-3-(trifluoromethyl)benzene-1-sulfonamide
InChI key:InChIKey=FANMQRSNMHKZCR-BKUYFWCQSA-N

分子式:C25H24F3N3O6S2
分子量:583.6
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1(CN2C(=O)S\C(=C/c3ccc(NS(=O)(=O)c4ccc(c(c4)C(F)(F)F)N(=O)=O)cc3)C2=O)CCCCC1
SMILES:CC1(CN2C(=O)S\C(=C/c3ccc(NS(=O)(=O)c4ccc(c(c4)C(F)(F)F)N(=O)=O)cc3)C2=O)CCCCC1

OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.

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