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HIT220913592
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HIT220913592
  • HIT ID:HIT220913592
  • Cas No:107431-28-7
  • 常用名:Enadoline (Free Base)
  • IUPAC:2-(1-benzofuran-4-yl)-N-methyl-N-[7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide
    IUPAC:2-(1-benzofuran-4-yl)-N-methyl-N-[7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide
  • InChI key:InChIKey=JMBYBVLCYODBJQ-UHFFFAOYSA-N
  • 分子式:C24H32N2O3
  • 分子量:396.531
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CN(C1CCC2(CCCO2)CC1N1CCCC1)C(=O)Cc1cccc2occc12
    SMILES:CN(C1CCC2(CCCO2)CC1N1CCCC1)C(=O)Cc1cccc2occc12
  • Enadoline (Free Base) is a kappa-opioid receptor agonist; PD 129290 (CAM 570; CI 977) is the S,S(-)-enantiomer; PD 129289 (CAM 569) is the corresponding R,R(+)-enantiomer. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist. There was mention of its potential in treating comatose head injury or stroke victims, where that type of side effect would be immaterial.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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