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HIT220913792
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HIT220913792
  • HIT ID:HIT220913792
  • Cas No:15148-80-8
  • 常用名:Bupranolol HCl
  • IUPAC:1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride
    IUPAC:1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride
  • InChI key:InChIKey=WJUUZHQWGKSLIJ-UHFFFAOYSA-N
  • 分子式:C14H23Cl2NO2
  • 分子量:308.24
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cl.Cc1ccc(Cl)c(OCC(O)CNC(C)(C)C)c1
    SMILES:Cl.Cc1ccc(Cl)c(OCC(O)CNC(C)(C)C)c1
  • Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely absorbed from the gut. Over 90% undergo first-pass metabolism. Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. The main metabolite is carboxybupranolol, 4-chloro-3-[3-(1,1-dimethylethylamino)-2-hydroxy-propyloxy]benzoic acid – that is, the methyl group at the benzene ring is oxidized to a carboxyl group –, of which 88% are eliminated renally within 24 hours.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    1-2周
    纯度
    -
    ¥ 10,600.00
    1

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