Gemfibrozil-d6 | CAS 1184986-45-5 | AnyMole

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HIT220913826

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HIT220913826

HIT ID:HIT220913826
Cas No:1184986-45-5
常用名:Gemfibrozil-d6
IUPAC:5-(2,5-dimethylphenoxy)-2,2-di(2H3)methylpentanoic acid
IUPAC:5-(2,5-dimethylphenoxy)-2,2-di(2H3)methylpentanoic acid
InChI key:InChIKey=HEMJJKBWTPKOJG-LIJFRPJRSA-N

分子式:C15H22O3
分子量:256.375
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[2H]C([2H])([2H])C(CCCOc1cc(C)ccc1C)(C(O)=O)C([2H])([2H])[2H]
SMILES:[2H]C([2H])([2H])C(CCCOc1cc(C)ccc1C)(C(O)=O)C([2H])([2H])[2H]

Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif ligand 2 (CCL2) in ApoE-/- mice. Formulations containing gemfibrozil have been used in the treatment of high cholesterol.

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TargetMolSC
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35日内发货
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-
¥ 3,490.00
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