• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT220921678
有库存
HIT220921678
 sdf 文件
结构编辑
类似物检索
HIT220921678
  • HIT ID:HIT220921678
  • Cas No:
  • 常用名:Taminadenant mesylate
  • IUPAC:5-bromo-2,6-bis(1H-pyrazol-1-yl)pyrimidin-4-amine; methanesulfonic acid
    IUPAC:5-bromo-2,6-bis(1H-pyrazol-1-yl)pyrimidin-4-amine; methanesulfonic acid
  • InChI key:InChIKey=MJTDDFFCYTWXRD-UHFFFAOYSA-N
  • 分子式:C11H12BrN7O3S
  • 分子量:402.23
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CS(O)(=O)=O.Nc1nc(nc(c1Br)-n1cccn1)-n1cccn1
    SMILES:CS(O)(=O)=O.Nc1nc(nc(c1Br)-n1cccn1)-n1cccn1
  • Taminadenant, also known as PBF-509 and NIR-178, is a potent and orally active adenosine A2A receptor antagonist with potential antineoplastic activity. PBF-509 selectively binds to and inhibits A2AR expressed on T lymphocytes. This abrogates the adenosine/A2AR-mediated inhibition of T-lymphocytes and activates a T-cell-mediated immune response against tumor cells, thereby reducing proliferation of susceptible tumor cells. A2AR, a G protein-coupled receptor, is highly expressed on the cell surfaces of T-cells and, upon activation by adenosine, inhibits their proliferation and activation. Adenosine is often produced in excess by cancer cells.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    1-2周
    纯度
    -
    ¥ 10,600.00
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层