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HIT220921685
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HIT220921685
  • HIT ID:HIT220921685
  • Cas No:1894207-45-4
  • 常用名:KDS2010 mesylate
  • IUPAC:(2S)-2-({[4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]methyl}amino)propanamide; methanesulfonic acid
    IUPAC:(2S)-2-({[4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]methyl}amino)propanamide; methanesulfonic acid
  • InChI key:InChIKey=AXIUZWFYRNNIFL-MERQFXBCSA-N
  • 分子式:C18H21F3N2O4S
  • 分子量:418.43
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CS(O)(=O)=O.C[C@H](NCc1ccc(cc1)-c1ccc(cc1)C(F)(F)F)C(N)=O
    SMILES:CS(O)(=O)=O.C[C@H](NCc1ccc(cc1)-c1ccc(cc1)C(F)(F)F)C(N)=O
  • KDS2010 is a potent, highly selective, and reversible MAO-B inhibitor which shows 12,500-fold selectivity over MAO-A. KDS2010 overcomes the disadvantages of the irreversible MAO-B inhibitor and significantly attenuates increased astrocytic GABA levels and astrogliosis, thereby enhancing synaptic transmission, and rescuing learning and memory impairments in APP/PS1 mice.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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