Others

Exp 631 is a centrally-acting non-opioid analgesic; exhibits serotonin and norepinephrine reuptake inhibiting activities.

(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.

Transketolase-IN-2（化合物4w）是一种强效的Transketolase抑制剂，对Digitaria sanguinalis和Amaranthus retroflexus展现出显著的抑制效果（200 mg/L浓度下抑制率超过90%，100 mg/L浓度下抑制率约为80%）。该化合物适用于研究杂草防治。

KSK213 is a potent inhibitor of Chlamydia trachomatis Infectivity (EC50 = 60 nM). KSK213 potently inhibited multiple serovars of C. trachomatis while not affecting the growth of key species from the commensal flora or host cell viability at 25 μM.

SCH-900822 is a potent and selective glucagon receptor antagonist.

I-BET469 is a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose.

Domipizone is a platelet aggregation inhibitor, cardiotonic and vasodilator.

U 72745G is an angiogenesis factor antagonist.

IND31119 is a novel selective inhibitor of PfHsp90, bypassing its highly similar human orthologs.

CDK8-IN-18, also known as ZINC584617986, is a potent and selective inhibitor of CDK8, also modulating CDK19.

L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity.

ICI-180080 is a thromboxane antagonist.

NBI-75043 is a histamine H1 receptor antagonist, for potential use in the treatment of insomnia.

Piragliatin, also known as RO4389620, is a glucokinase activator. Piragliatin greatly enhances glucose-induced pancreatic islet respiration and insulin release. Piragliatin lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus. Piragliatin has an acute glucose-lowering action in patients with mild type 2 diabetes, mainly mediated through a generalized enhancement of β-cell function and through fasting restricted changes in glucose turnover.

VEGFR-IN-V is a potent, vascular endothelial growth factor receptor-​2 (VEGFR-2) tyrosine kinase inhibitor.

Mk-0533是一种选择性过氧化物酶体增殖激活受体γ调节剂，用于治疗2型糖尿病。

Basic Blue 20是一种发红光DNA染料，以其激发光谱峰值为633 nm和发射光谱峰值为677 nm的特性，具有较窄的光谱范围。此外，Basic Blue 20还显示出高度的抗光漂白性。

DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT signal pathway in dose- and time-dependent manners both in vitro and in vivo. DC120 inhibits AKT activity in vitro with an EC(50) of 153 nM. DC120 at 20 mg/kg/day inhibited the CNE2 xenograft tumor growth with a treated group/control group ratio of 38.1%, accompanied by increasing terminal deoxynucleotidyl transferasedUTP nick-end labeling-positive cells in the tumor sample.

GRC-6211 is an oral specific TRPV1 antagonist which decreases bladder overactivity and noxious bladder input in cystitis animal models.

Cyclofos-3 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0013，CAS号为 823796-66-3。

TSRI265 is a novel αvβ3 ligand, disrupting the integrin-MMP2 interaction and showing antiangiogenic activit, inhibiting angiogenesis and tumor growth in vivo.

Apricoxib, also known as Benzenesulfonamide 42(4ethoxyphenyl)4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.

BML277 Acid is a metabolite of BML277 which is a selective checkpoint kinase 2 inhibitor.

NVP018, also known as BC 556, is a potent inhibitor of hepatitis B virus, hepatitis C virus (HCV), and HIV-1 replication, shows minimal inhibition of major drug transporters, and has a high barrier to generation of both HCV and HIV-1 resistance..

Manoalogue is a synthetic analog of manoalide and phospholipase A2 antagonist.

Lauryl Glucose Neopentyl Glycol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0033，CAS号为 1423318-02-8。

Exp 063 is a hybrid compound that possesses both the angiotensin II antagonist activity and the β-blocking activity. EXP 063 also acts as a partial β-agonist.

ToP-DNJ is a selective inhibitor of endoplasmic reticulum α-Glucosidase II, exhibiting antiflaviviral activity.

SR 27417A is a PAF-receptor antagonist.

1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate 是PEG脂质体，用于药物递送研究。

KNI-144 is a protease inhibitor.

A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.

Methophenazine diethanesulfonate is a Calmodulin antagonist.

CGS 23885 is a 5-lipoxygenase inhibitor.

Galdansetron hydrochloride is a serotonin antagonist and anti-emetic.

MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.