Others

Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleophiles

IDN-1965 is a potent, broad-spectrum, irreversible caspase inhibitor. IDN-1965 is markedly effective at inhibiting Fas-mediated apoptosis by multiple routes of administration. The therapeutic potential of caspase inhibitors appears promising for the treatment of apoptosis-mediated liver injury based on potency and postinsult efficacy.

3-(4-(2-Methoxyethyl)phenoxy)propane-1,2-diol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64642。

2S-[(4,4’-Dimethoxy trityloxy)methyl]oxirane 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1428，CAS号为 834906-31-9。

Methyl benzyl-L-valinate hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65057，CAS号为 177721-72-1。

CLR01 is a molecular tweezer. CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy. CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALS. CLR01 inhibits Ebola and Zika virus infection. CLR01 Stabilizes a Disordered Protein-Protein Interface. CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity.

UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 12–61 μM for exposure times of 72 h. There was also no selective inhibition of DNA, RNA or protein synthesis after exposure to UA8967. UA8967 is observed to affect the plasma membrane.

ditridecylamine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64749，CAS号为 101012-97-9。

6-Amino-3-iodo-2-methylpyridine belongs to Heterocyclic Compounds - Pyridine; Intermediates and Building Blocks - Electrophile.

QS inhibitor 2 is a novel potent inhibitor of quorum sensing (QS) pathways.

CI 959 is a novel antiallergic compound which is a potent inhibitor of receptor-mediated histamine release from human basophils. It inhibits thromboxanes.

Esmirtazapine HCl is the salt form of Esmirtazapine, a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors.

O-2,2'-Anhydro-5-methyluridine is a Nucleoside Derivative - Anhydro-nucleoside.

Nucleoside Derivatives - 3'-Modified nucleosides; Protected nucleosides with NH2/OH open; Ready for phosphorylation

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65517，CAS号为 479633-63-1。

1-[(5E)-3-O-[(Bis-di-isopropyl amino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.

BMS-961955 is an allosteric inhibitor of the hepatitis C virus NS5B polymerase.

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66336，CAS号为 93609-84-8。

(2S,3R)-3-(((Benzyloxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66397，CAS号为 59969-65-2。

5-Bromo-2-hydroxy-3-methyl pyrazine belongs to Heterocyclic Compounds - Pyrazine; Intermediate and Building Blocks - Electrophile.

CEP-6800 is a potent PARP inhibitor with potential anticancer activity. CEP-6800 could be used as a chemopotentiating agent with a variety of clinically effective chemotherapeutic agents.

AQ-101 is a inhibitor of MDM2, which induces MDM2 protein degradation through a self-ubiquitination and proteasome-mediated mechanism.

2-(3,4-Dimethoxyphenyl)-3-methylbutanenitrile 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65858，CAS号为 20850-49-1。

Di(thiophen-2-yl)methanone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67376，CAS号为 704-38-1。

Mexrenoate potassium is a steroidal aldosterone antagonist and antihypertensive.

Amipizone is a phosphodiesterase inhibitor.

Bicifadine, also known as DOV-220075, CL 220,075, is a SNDR inhibitor potentially for the treatment of lower back pain. Bicifadine has a non-opioid, non-NSAID mechanism for the treatment of pain, which should have less abuse potential than opioid drugs and less propensity to cause gastric ulcers than NSAID drugs. While the drug is purported to be a serotonin (SERT) and noradrenaline transporter (NET) inhibitor, it also has effects at the dopamine transporter (DAT), effectively making it a broad-spectrum monoamine transporter inhibitor or triple reuptake inhibitor.""

4-Nitrophthalic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67120，CAS号为 610-27-5。

FT-1101 is an orally bioavailable, potent and selective BET inhibitor. FT-1101 binds to the acetylated lysine recognition motifs in the bromodomain sites of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histones. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to the inhibition of tumor cell growth. BET proteins, comprised of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth.

Heptyl-β-D-Selenoglucoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0072，CAS号为 1423272-15-4。

MDL-28133A is a 5-HT2 receptor antagonist.

N-benzyloxycarbonyl-3-fluoro-4-morpholinoaniline 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65629，CAS号为 168828-81-7。

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67466，CAS号为 130049-82-0。

1-(4-Chlorophenyl)biguanide hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67045，CAS号为 4022-81-5。

Oxprenoate Free Base is a mineralocorticoid receptor (MR) antagonist, inhibiting aldosterone production and secretion.

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66488，CAS号为 18592-13-7。