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Advanced Glycation End Products
CYP19A1
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Platelet aggregation
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Targetmol为生命科学及医药领域的科研人员提供其他未细分细胞信号通路相关产品,包括抑制剂、激动剂、调节剂、降解剂等。
HIT213163413
4-Chloro-5-(p-tolyl)-1H-imidazole-2-carbonitrile
T66379
4-Chloro-5-(p-tolyl)-1H-imidazole-2-carbonitrile 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T66379。
Others
HIT103858552
3-Methoxy-2-methyl-4H-pyran-4-one
T66414
4780-14-7
3-Methoxy-2-methyl-4H-pyran-4-one 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66414,CAS号为 4780-14-7。
Others
HIT217588288
BVB-808
T71313
1180158-99-9
BVB-808 is a selective Jak2 type 1 inhibitor. Janus kinases are critical components of signaling pathways that regulate hematopoiesis. Mutations of the non-receptor tyrosine kinase JAK2 are found in many BCR-ABL-negative myeloproliferative neoplasms. Preclinical results support that JAK2 inhibitors could show efficacy in treating chronic myeloproliferative neoplasms. JAK2 has also been postulated to play a role in BCR-ABL signal transduction. Therefore, inhibitors of JAK2 kinases are turning into therapeutic strategies for treatment of chronic myelogenous leukemia (CML).
Others
HIT211999909
PS77
T71939
1450888-35-3
PS77 is a Pkh inhibitor directed to the PIF-pocket with increased selectivity for C. albicans Pkh2.
Others
HIT107159990
Pifexole
T71882
27199-40-2
Pifexole is the 1,2,4-oxadiazole derivative. It has a similar profile of muscle-relaxant activity in animals to that of chlorzoxazone. In rats, pifexole is reported to be seven times more potent than chlorzoxazone in inhibition of strychnine-induced convulsions.
Others
HIT102657779
tert-Butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate
T67609
877399-50-3
tert-Butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67609,CAS号为 877399-50-3。
Others
HIT217590723
Dotarizine
T68580
84625-59-2
Dotarizine is a 5-HT2 receptor antagonist; active metabolite, FI 6020, detected by gas chromatography.
Others
HIT213354089
tert-Butyl 7-hydroxyheptanoate
T64763
tert-Butyl 7-hydroxyheptanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64763。
Others
HIT102531539
Hexbutinol
T71315
117828-61-2
Hexbutinol is an inhibitor of muscarinic receptors.
Others
HIT214434390
5-Hydroxymethyl-2-thiouracil
TNU0700
93185-31-0
Heterocyclic compound - pyrimidine; building block - nucleobase
Others
HIT106861714
3,5-Dimethyl-4-nitropyridine 1-oxide
T67494
14248-66-9
3,5-Dimethyl-4-nitropyridine 1-oxide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67494,CAS号为 14248-66-9。
Others
HIT214308903
N6-Boc-adenin-9-yl acetic acid
TNU0890
186046-99-1
N6-Boc-adenin-9-yl acetic acid is a PNA-related Derivative; PNA monomer.
Others
HIT214433968
(R)-1,4-Anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-sulfinyl-D-ribitol
TNU1108
291758-13-9
Carbohydrate Derivatives; Ready for glycosylation
Others
HIT214432854
5-Trifluoromethyluracil-1-yl acetic acid methyl ester
TNU1054
2072152-16-8
5-Trifluoromethyluracil-1-yl acetic acid methyl ester is a PNA-related Derivative.
Others
HIT212089118
4-Fluorocinnamic acid
T64996
459-32-5
4-Fluorocinnamic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64996,CAS号为 459-32-5。
Others
HIT217590949
AS1940477
T68321
928344-12-1
AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent concentrations of AS1940477 that inhibited cytokine production also inhibited TNFα- and IL-1 β-induced production of IL-6, PGE(2), and MMP-3 in human synovial stromal cells. AS1940477 was also found to potently inhibit TNF production in whole blood (IC(50)=12 nM) and effectively inhibited TNFα production induced by systemically administered LPS in rats at less than 0.1mg/kg (ED(50)=0.053 mg/kg) with an anti-inflammatory effect lasting for 20h after oral administration. Overall, this stu......
Others
HIT212000600
H-Ile-OAll.TosOH
T66249
88224-05-9
H-Ile-OAll.TosOH 是一种氨基酸衍生物,在生命科学相关研究中具有广泛的应用。
Others
HIT213834751
tert-Butyl 7-iodoheptanoate
T64707
tert-Butyl 7-iodoheptanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64707。
Others
HIT217590895
KD026-metabolite
T68375
913541-44-3
KD026-metabolite, is a metabolite of KD-026. KD026, also known as SLx-4090, is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes.
Others
HIT213127047
iso-Dehydrozingerone
T69778
22214-39-7
iso-Dehydrozingerone is a novel osteoclastogenesis inhibitor, preventing ovariectomy-induced osteoporosis in ddY mice.
Others
HIT212089237
2-Methylcinnamic acid, predominantly trans
T65873
2373-76-4
2-Methylcinnamic acid, predominantly trans 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65873,CAS号为 2373-76-4。
Others
HIT101721910
5-Bromo-2-fluorobenzonitrile
T66892
179897-89-3
5-Bromo-2-fluorobenzonitrile 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66892,CAS号为 179897-89-3。
Others
HIT217588721
Neratinib dimethylamine N-oxide
T70830
1376615-55-2
Neratinib dimethylamine N-oxide is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity.
Others
HIT103300999
F2276-0099
T71724
921995-90-6
F2276-0099 is a PCAF/GCN5 BRD inhibitor
Others
HIT105364701
2-(Chloromethyl)-4-methylquinazoline
T65621
109113-72-6
2-(Chloromethyl)-4-methylquinazoline 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65621,CAS号为 109113-72-6。
Others
HIT217589513
BIM-46068
T69993
201487-53-8
BIM-46068 is a potent and specific inhibitor of human farnesyltransferase. In regard to a panel of cell lines, using the Compare analysis to determine the Pearson coefficient correlation, the anti-proliferative spectrum of BIM-46068 has been shown to be distinct from the profile of typical chemotherapeutic agents.
Others
HIT214432967
(S)-DMT-glycidol-A(Bz)
TNU1545
115196-70-8
(S)-DMT-glycidol-A(Bz) is a Nucleoside Derivative - Acyclic nucleoside.
Others
HIT212000505
(S)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione
T65826
189028-93-1
(S)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65826,CAS号为 189028-93-1。
Others
HIT217590354
Falipamil hydrochloride
T69004
60987-07-7
Falipamil hydrochloride is a calcium channel antagonist potentially for the treatment of ischaemic heart disorder and sinus.
Others
HIT106880528
2,5-Bis(trifluoromethyl)aniline
T67116
328-93-8
2,5-Bis(trifluoromethyl)aniline 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67116,CAS号为 328-93-8。
Others
HIT106061261
2-Amino-4-methoxyphenol
T67355
20734-76-3
2-Amino-4-methoxyphenol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T67355,CAS号为 20734-76-3。
Others
HIT102205463
tert-Butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate
T66074
414910-15-9
tert-Butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66074,CAS号为 414910-15-9。
Others
HIT212000648
(1S)-(+)-(10-Camphorsulfonyl)oxaziridine
T65662
104322-63-6
(1S)-(+)-(10-Camphorsulfonyl)oxaziridine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65662,CAS号为 104322-63-6。
Others
HIT213629450
AGI25696
T69811
2201065-84-9
AGI-25696 is a MATA2 inhibitor that are useful as therapeutic agents for treating malignancies. AGI-25696 showed in vivo activity in MTAP null tumors. Note: The correct structure of AGI-25696 is CAS#2201065-84-9. Many vendors mistakenly listed CAS#2201066-35-3 as its AGI25696. J. Med. Chem. 2021, 64, 8, 4430–4449 published AGI25696 structure (it is CAS#2201065-84-9).
Others
HIT213831024
N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-3-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
T64786
1628530-41-5
N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-3-hydroxyphenyl)cyclopropane-1,1-dicarboxamide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64786。
Others
HIT214432677
4-Hydroxy-2-oxo-1(2H)-pyridineacetic acid
TNU1063
90597-00-5
4-Hydroxy-2-oxo-1(2H)-pyridineacetic acid is a PNA-related Derivative.
Others
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