钙离子探针

Arsenazo I is a calcium-sensitive, metallochromic dye used as reagent.

Quin-2AM is a fluorescent Ca2+ chelator with a high affinity for calcium.

Fluo-3 (ammonium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. [1] Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.

BTC AM is a cell-permeable acetoxy-methyl ester of BTC . As BTC AM enters cells, it is hydrolyzed by intracellular esterases to produce BTC. BTC is a low affinity calcium indicator (Kd = 7-26 μM) that displays excitation/emission spectra of 401/529 nm, respectively. It exhibits a shift in the excitation maximum from approximately 480 to 401 nm upon calcium binding, enabling determination of ratiometric calcium measurements. BTC is suitable for detecting elevated calcium levels associated with activation of smooth muscle, neurons, and intracellular calcium stores.

Calcium Green BAPTA-2 AM serves as a fluorescent indicator for calcium ions.

PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].

BAPTA tetrapotassium是一种选择性的钙离子螯合剂，还能够抑制phospholipase C的活性,可用于研究细胞内钙稳态、控制细胞毒性和控制金属离子干扰。

Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) 是 Rous 相关病毒 2 逆转录酶的抑制剂。 Alizarin Complexone 可用作生物研究的钙示踪剂和螯合剂。

Rhod-FF AM是一种细胞渗透性的荧光钙离子指示剂，能够被细胞内酯酶水解生成rhod-FF，Ex/Em=552/580 nm。Rhod-FF AM与Ca²⁺的结合亲和力较低，可用于10-200 μM浓度范围的较高浓度钙离子检测。

FURA-PE3/AM 为一款防漏型荧光钙离子指示剂染料。

Calcium Green-5N AM 是一种新型对Ca2+敏感的荧光探针，在结合Ca2+时显示荧光强度增强，可用于监测神经元中游离的Ca2+。

Arsenazo III is a dye used to detect micromolar concentrations of ionized Ca2+ and for determining thorium, zirconium, uranium, and rare earth elements [1] [2].

BTC tetrapotassium是一种钙指示剂，其Kd值约为7-26 µM，表现出低亲和力。它拥有适合细胞钙成像的特性，如长激发波长（400/485 nm），低对Mg2+的灵敏度，以及用于比率测量的高准确性。

Coelenterazine E is a bioluminescent probe.

Fluo-4 potassium 是一种可渗透细胞的Ca2+探针 (λex=494 nm, λem=516 nm)。

Calmagite 是络合指示剂，可用于多种样品中的钙和镁的检测。

Alizarin Red S sodium (ARS sodium) 是一种蒽醌类染料，在检测细胞培养中的钙沉积具有广泛的应用。

Coelenterazine hcp is a synthetic bioluminescent luciferin that displays an emission maximum of 445 nm.1It has been used as a calcium indicator and substrate to quantifyRenillaluciferase activity.1,2,3 1.Sabnis, R.W.Handbook of biological dyes and stains: Synthesis and industrial applications(2010) 2.Shimomura, O., Kishi, Y., and Inouye, S.The relative rate of aequorin regeneration from apoaequorin and coelenterazine analoguesBiochemistry Journal296(Pt 3)549-551(1993) 3.Pichler, A., Prior, J.L., and Piwnica-Worms, D.Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazineProc. Natl. Acad. Sci. USA.101(6)1702-1707(2004)

Coelenterazine h (CLZN-h) 是一种 Coelenterazine 的衍生物。它对 Ca2+比它的天然复合物更敏感，是一种能够测量 Ca2+浓度的微小变化的有效工具。

5,5'-Dimethyl BAPTA tetrapotassium是一种水溶性的细胞膜外金属螯合剂，对钙离子具有相对选择性。

5,5'-Dibromo BAPTA tetrapotassium是一种钙离子螯合剂，可以配成具有确切钙离子浓度的缓冲液，并能控制细胞内外的钙离子浓度，适用于钙生理活性的研究。

Fluo-3AM is a calcium indicator that exhibits an increase in fluorescence upon binding Ca2+. It is used to image the spatial dynamics of Ca2+ signaling in flow cytometry experiments.

Fluo-2 AM (Fluo-2 acetoxymethyl ester) 为细胞内钙离子浓度监测应用的一种荧光染料.

Indo-1 (potassium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when Indo-1 (potassium salt) binds calcium. Indo-1 (potassium salt) is prone to photobleaching, which limits its usefulness in methods involving microscopy.

Rhod-2 (potassium salt) is a water-soluble, red fluorescent calcium indicator. It exhibits a significant shift in fluorescence intensity upon calcium binding (ex max = 549 nm; calcium-free v. ex/em max = 552/581 nm; calcium-bound). Unlike the UV-excitable indicators fura-2 and indo-1 , there is no accompanying spectral shift.

C.I. 15670是一种颜料，为红紫色粉末。可用于油墨、染料激光器、乙烯基聚合物制造、纺织品铁、钙、铝、钽的测定、工业水中硬度的监测、饮用水中二氧化氯的测量、降血糖剂、核荧光染料等。

BAPTA-TMFM为研究胞质游离钙行为专用的荧光螯合指示剂。