Others

alpha-Amyl cinnamaldehyde is a common additive in the perfume and cosmetic industry as an aroma substance.

ADL-5747, an opioid delta receptor agonist, is used potentially for the treatment of pain.

Allylpyrocatechol is an antioxidant. Allylpyrocatechol attenuates collagen-induced arthritis via attenuation of oxidative stress secondary to modulation of the MAPK, JAK/STAT, and Nrf2/HO-1 pathways.

ABP-700 is a positive allosteric modulator of the GABAA receptor.

A 62198 is a potent and selective renin inhibitor with potential as a hypotensive agent.

AC-4 is a blocker of photoswitchable TRPV1 channel.

AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.

AZD7268 is a potent, selective, reversible, and orally bioavailable agonist of δ-opioid receptor with CNS penetration.

A 85 4777, a homoperazine derivative, is an anti-inflammatory agent with nonclassical immunosuppressive properties.

A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication.

DBPR-110 is a nonstructural protein 5A (NS5A) inhibitor. DBPR-110 reduced the reporter expression of the HCV1b replicon with a EC(50) and a selective index value of 3.9 ± 0.9 pM and >12,800,000, respectively. DBPR-110 reduced HCV2a replicon activity with

NEU-730, a novel inhibitor of TbrPDEB1, shows modest inhibition of T. brucei proliferation.

Delequamine HCl is a potent and selective alpha 2-adrenoceptor antagonist. Delequamine HCl has a pKi of 9.45 for alpha 2-adrenoceptors in the rat cortex (pA2 in the guinea-pig ileum of 9.72).

Ifoxetine sulfate, a 5-HT uptake inhibitor with atypical effects on serotonin uptake, may exhibit a therapeutic and/or side-effect profile which differs from that of classical 5-HT uptake inhibitors.

Chinfloxacin, a quinolone antibiotic, is used potentially for the treatment of bacterial infections.

Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.

GS-9851, a HCV nonstructural protein 5B (NS5B) inhibitor, is used potentially for the treatment of HCV infection.

GW0072 is a partial agonist of PPARγ.

Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.

MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.

ND-2110, a selective interleukin-1 receptor-associated kinase 4 inhibitors, is used for the treatment of autoimmune disorders and lymphoid malignancy.

ICI-56780, a antimalarial agent, displays blood schizonticidal activity against P.berghei.

HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.

JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.

Chlorpropylate is an insecticide.

CP-944629 is a novel, potent, and selective inhibitor of p38alpha.

CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain.

BNC-1 is a modulator of amyloid pathology. BNC-1 significantly decreases amyloid burden and improves markers of synaptic integrity in well-established mouse models of amyloid deposition by promoting phosphorylation and activation of Elk-1.

Bromadoline is an opioid analgesic selective for the μ-opioid receptor.

CAY10397, a selective inhibitor of 15-hydroxy PGDH, significantly suppresses endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE.

CGI-17341 is an orally active representative of the 5-nitroimidazole series of antimicrobial agents. CGI 17341 inhibits the drug-susceptible and multi-drug-resistant strains of Mycobacterium tuberculosis at concentrations ranging from 0.1 to 0.3 microgram

CGP-28014 is an inhibitor of catechol-O-methyltransferase. CGP-28014 increases the renal excretion of both dopamine and dihydroxyphenylacetic acid (DOPAC) but does not affect renal sodium handling indicating a different mechanism of action. CGP-28014 sign

CGP 47656 is an agonist of GABAB receptor.

Allosamidin, a chitinase inhibitor and typical secondary metabolite of Streptomyces, may be used as a pesticide and anti-asthmatic agent.

BRL 55834, a potassium channel activator, has shown to relax airways and vasculature in vivo.

Diethylumbelliferyl phosphate (DEUP) 作为一种选择性的强效胆固醇酯酶抑制剂，能防止胆固醇被运输到类固醇生成细胞的线粒体，从而有效抑制类固醇的生成。在体外环境中，DEUP不会对蛋白激酶活性A造成抑制。此外，其IC50值为 11.6 μM，表明该化合物能够在一定程度上阻止膳食胆固醇的吸收。