Others

(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.

G-749 hydrochloride is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type and mutants including FLT3-ITD, FLT3-D835Y, FLT3-ITD/N676D, and FLT3-ITD/F691L in cellular assays.

Fasoracetam monohydrate is a small synthetic molecule and a metabotropic glutamate receptor activator, which has previously undergone extensive Phase I-III clinical trials in humans for vascular dementia.

Tylogenin, a steroidal aglycone generated by acid hydrolysis from two seasonal glycosides occurring in Tylophora sylvatica, inhibits IgE-induced basophil mediator release for allergic reactions. In the rabbit basophil-dependent serotonin release (BDSR) assay system, the inhibitory activity of tylogenin was significantly greater than that of its parent glycosides, tylophoroside and acetyltylophoroside, and that of dexamethasone. The activity of tylogenin was found to increase with the incubation time. In the human leukocyte-dependent histamine release test model, the glycosides had only a minimal activity. In contrast, tylogenin, with a geom mean IC50 = 49 microM, exerted a significantly greater potency than dexamethasone. These results suggest that tylogenin could represent a new class of antiallergic agents.

AZD1446 tosylate, also known as TC-6683, is a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders. AZD1446 tosylate showed favorable pharmaceutical properties and in vivo efficacy in animal models has been identified as a potential treatment for cognitive deficits associated with psychiatric or neurological conditions and had been evaluated in phase 2 clinical trials as a treatment for Alzheimer's disease.

AZD6564 is a fibrinolysis inhibitor which acts via interference of a protein-​protein interaction.

Viriditoxin is a secondary metabolite isolated from Aspergillus viridinutans that has been shown to inhibit FtsZ, the bacterial homologue of eukaryotic tubulin.

Clentiazem (free base) is a calcium channel blocker. It is a chlorine derivative of diltiazem.

Nizatidine amide is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.

NOSO-95C is an antibacterial compound that bind to the bacterial ribosome and kill bacteria through inhibition of the translation. NOSO-95C showed promising in vitro and in vivo efficacy against Enterobacteriaceae.

Brovincamine also known as brovincamine fumarate (BV, Sabromin) was used in Japan mainly as an improver of cerebral circulation and metabolism, and also as an inhibitor of the aggregation of platelets through the cyclic AMP pathway in patients with normal tension glaucoma. Brovincamine exerts its action via calcium channels blockade. Brovincamine is also a vasodilator.

Tripao 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0088，CAS号为 318293-46-8。

Demethyl bleomycin A2 是Bleomycin 的同源物。Demethyl bleomycin A2 的 DNA 裂解对5-Methylcytidine 不敏感。

Eglin c (60-63) is a sequence of a peptide that has been studied for its inhibitory activity towards human leukocyte elastase, cathepsin G, porcine pancreatic elastase and alpha-chymotrypsin.

F-15599 tosylate is a selective 5-HT(1A) agonist.

AMG0074 is a PDE10 antagonist.

FT385 is a novel USP30 inhibitor, recapitulating genetic loss of USP30 and setting the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

ICSN3250 is a novel specific mTOR inhibitor via a unique mechanism which is distinct from previous mTOR inhibitors.

Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cromoglicic acid requires administration four times daily, and does not provide additive benefit in combination with inhaled corticosteroids.

RKS262 is a specific cyclin/CDK inhibitor. RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. In a NCI(60) cell-line assay RKS262 exhibited significant cytotoxicity in ovarian cancer cells and a variety of other cell lines exceeding effects of commercial drugs such as cisplatin, 5-FU, cyclophosphamide or sapacitabine. Various leukemia cell-lines were most sensitive (GI(50): ~ 10 nM) while several non-small cell lung cancer cell lines and few cell lines from other tissues were relatively resistant (GI(50) > 1 µM) to RKS262 treatment.

AD2765, also known as AD 2845 and Sphingosylphosphoryl​ ​choline, is a novel thiourea derivative of sphingomyelin that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death.

Caparratriene is a new sesquiterpene hydrocarbon isolated from Ocotea caparrapi with potential for significant growth inhibitory activityagainst CEM leukemia cells

Flufenacet is a herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis.

3-Hydroxypregna-5,16-dien-20-one 3-acetate是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T131711，CAS号为 38521-84-5。

C.I. Azoic Coupling Component 5 is an indicator of fluorescent.

Naringenin-6-C-glucoside是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T131719，CAS号为 3682-03-9。

Compound 8H is an inducer of G2/M-phase cell cycle arrest and cell death in cancer cell lines.

4-((benzo[g]quinolin-4-yl(methyl)amino)methyl)-N,N-dimethylbenzenesulfonamide是一种化学试剂。

3-(4-Hydroxyphenyl)propan-2-one是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2532，CAS号为 117614-84-3。

Quinovic acid 3-O-(3',4'-O-isopropylidene)-beta-D-fucopyranoside是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4885，CAS号为 182132-59-8。

2-Hydroxy-3-(hydroxymethyl)anthraquinone 在 Hepa lclc7 细胞中表现出醌还原酶 (QR) 诱导活性，其 QR 活性加倍所需的浓度为 0.94 microM。

1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine是一种天然产物，属于莲叶桐科莲叶桐属，其产品编号为 TN2479，CAS号为 872729-33-4。1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine可用作对照参考。

2',4',5'-TriMethoxy-2'',2''-diMethylpyrano[5'',6'':6,7]isoflavone是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2708，CAS号为 211799-56-3。

Melatonin Biotin是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64745。

13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide is a natural product from Artemisia myriantha.

Methyl 2-(6-acetyl-5-hydroxy-2,3-dihydrobenzofuran-2-yl)propenoate is a natural product from Vernonia cinerea.