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供应商货号
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供应商货号
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化合物库
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Advanced Glycation End Products
CYP19A1
Decarboxylase
DprE1
Fer/FerT kinase
Platelet aggregation
Progesterone Receptor
Others
信号通路
其他
Others
Others
Targetmol为生命科学及医药领域的科研人员提供其他未细分细胞信号通路相关产品,包括抑制剂、激动剂、调节剂、降解剂等。
HIT212712654
Fosfluridine tidoxil
T27349
174638-15-4
Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.
Nucleoside Antimetabolite/Analog
Others
HIT213954695
2′-Deoxy-5-nitrocytidine
T60476
69100-02-3
2′-Deoxy-5-nitrocytidine 是一种 DNA 甲基转移酶(DNMT)的抑制剂,可用于癌症领域研究。
DNA Methyltransferase
Others
HIT214433924
7-Deaza-2',3'-dideoxyguanosine
T60371
111869-49-9
7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) 是一种 2',3'-dideoxynucleoside 5'-triphosphate,抑制HIV-1逆转录酶,Ki 值为 25 nM。
HIV Protease
Others
HIT212713888
Valnivudine
T29092
956483-02-6
Valnivudine 是 CF-1743 的前体,是一种口服有效和高效的抗带状疱疹 (HZ) 核苷类似物, 是一种双环核苷类似物 (BCNA). Valnivudine 具有抗病毒活性,可对水痘带状疱疹病毒 (VZV) 进行高度抑制。Valnivudine 在体内可以迅速广泛地转化为 CF-1743。
Antibacterial
Antibiotic
Others
HIT214324007
ddGTP
T40799
68726-28-3
ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing.
Others
HIT214323988
5-Propargylamino-3'-azidomethyl-dUTP
T40770
666847-57-0
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule. It finds applications in DNA synthesis and sequencing.
DNA/RNA Synthesis
Others
HIT214323989
5-Propargylamino-3'-azidomethyl-dCTP
T40771
666847-71-8
5-Propargylamino-3'-azidomethyl-dCTP, is a nucleoside molecule. It finds utility in DNA synthesis and DNA sequencing.
DNA/RNA Synthesis
Others
HIT214323956
7-Methyl-diguanosine triphosphate
T40722
62828-64-2
7-Methyl-diguanosine triphosphate (m7Gp3G) is a cap analog that integrates into mRNA, playing a crucial role in translation and mRNA degradation within mammalian cells.
DNA/RNA Synthesis
Others
HIT214323322
8-Br-GTP
T39857
23197-98-0
8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification.
Antibacterial
Others
HIT214322611
5-Fluorouridine 5'-O-β-D-galactopyranoside
T38987
149965-92-4
5-Fluorouridine 5'-O-β-D-galactopyranoside, also known as 5'-O-β-D-galactosyl-5-fluorouridine, is a prodrug of 5-Fluorouridine. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, which is a highly effective antineoplastic agent.
Others
HIT211998778
2,6-Dichloropurine-9-β-D-riboside
T35655
13276-52-3
2,6-Dichloropurine-9-β-D-riboside is a building block.1,2It has been used in the synthesis of photoaffinity probes for nucleotide binding sites in proteins. 1.Wower, J., Hixson, S.S., Sylvers, L.A., et al.Synthesis of 2,6-diazido-9-(β-D-ribofuranosyl)purine 3',5'-bisphosphate: Incorporation into transfer RNA and photochemical labeling of Escherichia coli ribosomesBioconjug. Chem.5(2)158-161(1994) 2.Seiter, M.S., Bauer, M.P., Bogel, P.D., et al.Synthesis of novel spin-labeled photoaffinity derivatives of NAD+ and ATP and their characterization as coenzymes and substrates of several enzymesSynthesis2269-273(1996)
Others
HIT214324188
pNP-ADPr
T41083
939028-75-8
pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose) polymerase (PARP) enzymes.
Others
PARG(Poly(ADP-ribose) Glycohydrolase)
HIT214324204
EFdA-TP
T41110
950913-56-1
EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.
DNA/RNA Synthesis
HIV Protease
Others
Reverse Transcriptase
HIT212664734
S-Adenosyl-DL-Methionine
T4116
17176-17-9
S-Adenosyl-DL-Methionine (Ademetionine) 是一种 Ademetionine 的衍生物。其中Ademetionine 是蛋氨酸的中间代谢产物。
Others
HIT214323468
Nicotinamide riboside tartrate
T40059
2415657-86-0
Nicotinamide riboside tartrate (NRT) is an oral NAD+ precursor that raises NAD+ levels, activates SIRT1 and SIRT3, and serves as a vitamin B3 (niacin) source. NRT also improves oxidative metabolism and protects against metabolic abnormalities induced by a high-fat diet. Furthermore, NRT mitigates cognitive decline in a transgenic mouse model of Alzheimer's disease.
Endogenous Metabolite
Others
Sirtuin
HIT214323128
Orotidine 5′-monophosphate
T39626
2149-82-8
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase.
Endogenous Metabolite
Others
HIT214322447
Mant-GTPγS
T38782
136749-24-1
Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.
AChR
Others
HIT219592018
7-Deaza-7-propargylamino-ddGTP 3TEA
T38529L
7-Deaza-7-propargylamino-ddGTP 3TEA是一种ddGTP的衍生物和修饰核苷酸,可用于基因测序。ddGTP是Sanger测序中使用的链终止子之一。
Others
HIT214318779
Valopicitabine dihydrochloride
T29094
640725-71-9
Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.
HCV Protease
Nucleoside Antimetabolite/Analog
Others
HIT214318912
Adenosylselenomethionine
T29654
5134-38-3
Adenosylselenomethionine relates to metabolism of selenomethionine.
Others
HIT212714159
2-Ethynyl Adenosine
T29347
99044-57-2
2-Ethynyl Adenosine is an Adenosine derivative that is used to capture novel polyadenylated transcription and non-radiochemical reporter molecules of the protein AMPylation.
Others
HIT212714486
AGR-540
T29730
104124-23-4
AGR-540 is a prodrug of AGR-529. AGR-540 has been shown to return plasma triglyceride concentrations to normal levels in mouse models. This effect may be attributed to an interaction of the molecule with A1 purinergic receptors of adipose tissue.
Others
HIT212718712
Wyosine triacetate
T35146
68768-34-3
Wyosine triacetate is a biochemical.
Others
HIT212718493
Torcitabine
T34904
40093-94-5
Torcitabine is useful against the hepatitis B virus.
HBV
Others
HIT106291243
2′,3′,5′-Tri-O-acetyl Guanosine
T67464
6979-94-8
2′,3′,5′-Tri-O-acetyl Guanosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67464,CAS号为 6979-94-8。
Others
HIT220911937
Vincapusine
T68674
80248-97-1
Vincapusine is a natural inhibitor of 3C-like protease (3CLpro), targeting SARS-CoV-2 3CLpro, SARS-CoV 3CLpro and MERS-CoV 3CLpro.
Others
HIT212652324
NADP sodium salt
T6851
1184-16-3
NADP sodium salt (Sodium NADP) 是一种烟酰胺腺嘌呤二核苷酸,是一种氧化还原辅助因子。它是代谢中电子转移的关键辅因子,能够被交替氧化 (NADP+) 和还原 (NADPH)。
Endogenous Metabolite
Others
HIT214437935
5'-Deoxy-5'-N-(2-chloroethyl)aminothymidine
TNU1404
2305415-99-8
5'-Deoxy-5'-N-(2-chloroethyl)aminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
Nucleoside Antimetabolite/Analog
Others
HIT212685156
PAPS
T33880
482-67-7
PAPS is a product of mitosomal sulfate activation which is translocated to the cytosol, then becomes a substrate for SULTs.
Others
HIT212718260
SGC3027N
T34629
SGC3027N is a negative control for SGC3027 (GLXC-12451).
Others
HIT214436126
ZIKV-IN-1
T63131
2762166-06-1
ZIKV-IN-1 是一种 zika virus 的有效抑制剂 (EC50: 2.8 μM, EC90: 6.8 μM)。ZIKV-IN-1 具有抗 ZIKV 作用,且细胞毒性低。ZIKV-IN-1 对 ZIKV RdRp 结构域表现出很高的亲和力。
Anti-infection
Others
Virus Protease
HIT212718608
Valyl adenylate
T35031
52435-65-1
Valyl adenylate is a peptide.
Others
HIT212715501
CV-1674
T31115
37151-17-0
CV-1674 induced selective coronary vasodilation and had little effect on cardiac hemodynamics.
Others
HIT214319321
ddC-AZT dimer
T31231
121892-89-5
ddC-AZT dimer is a biochemical.
Others
HIT214437930
3'-O-Me-C(Bz)-2'-phosphoramidite
TNU1381
179479-03-9
3'-O-Me-C(Bz)-2'-phosphoramidite is a Nucleoside Phosphoramidite.
Nucleoside Antimetabolite/Analog
Others
HIT214319779
L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine
T32816
125780-83-8
L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine is a bioactive chemical.
Others
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