Others

Methyl diethylphosphonoacetate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65304，CAS号为 1067-74-9。

Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively. Lin et al (2011) Design, synthesis, and evaluation of 2-diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein conjugate (8MDP-fluor), as a novel equilibrativ Bioconjug.Chem. 22 1221 PMID:21539390 |Lin et al (2007) Synthesis, flow cytometric evaluation, and identification of highly potent dipyrid. analogues as equilibrative nucleoside transporter 1 inhibitors. J.Med.Chem. 50 3906 PMID:17636949

Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. It belongs to the calcitonin family of peptides, which also includes amylin , calcitonin gene-related peptide , and adrenomedullin. The binding of salmon calcitonin to the human calcitonin receptor (CTR) is not modulated by receptor activity-modifying proteins (RAMPs), which influence affinity of human calcitonin to CTR. Salmon calcitonin binds to human CTR2 with IC50 values of 0.933, 0.224, 0.134, and 0.317 nM alone and with RAMP1, 2, or 3, respectively. It induces cAMP accumulation in COS-7 cells transfected with CTR2 (EC50 = 0.166 nM). Salmon calcitonin inhibits bone resorption by osteoclasts in a pit formation assay using rat bone slices (ID50 = 0.003 pg/mL) and lowers calcium level in vivo in a bioassay of hypocalcemia in rats (ED15 = 33.9 mg/kg). Formulations containing salmon calcitonin have been used to treat hypercalcemia, bone destruction by osteoporosis, and Paget's disease.

HaXS8 is a dimerizer that facilitates the covalent and irreversible intracellular dimerization of proteins of interest labeled with HaloTag and SNAP-tag. Furthermore, HaXS8 does not exhibit any interference with PI3K/mTOR signaling.

Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance in adipocytes. Ganglioside GM3 mixture contains ganglioside GM3 molecular species with C18:1 and C20:1 fatty acyl chains.

6-Methylnicotinic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67013，CAS号为 3222-47-7。

2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).1 1.Qiu, Y.-L., Ksebati, M.B., Ptak, R.G., et al.(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activityJ. Med. Chem.41(1)10-23(1998)

1-(4-Nitrophenyl)ethanone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67687，CAS号为 100-19-6。

Methyl 3-hydroxydecanoate 可用于生命科学领域的相关研究。其产品编号为 T37676，CAS号为 62675-82-5。

5-HT2A agonist

Big Chap 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0096，CAS号为 86303-22-2。

Pentaethylene Glycol Monooctyl Ether (C8E5) 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0037，CAS号为 19327-40-3。

Imidazole hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65251，CAS号为 1467-16-9。

Sodium hexane-1-sulfonate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67132，CAS号为 2832-45-3。

n-Decyl-β-D-Thioglucopyranoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0057，CAS号为 98854-16-1。

n-Heptyl β-D-glucopyranoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66686，CAS号为 78617-12-6。

Dodecyltrimethylammonium chloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65559，CAS号为 112-00-5。

Sodium pentane-1-sulfonate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67149，CAS号为 22767-49-3。

Proxan-sodium is an agent of biochemical.

Benzyl dimethyl stearyl ammonium chloride hydrate is a kind of mild smell chemical

(2,6-Dichlorophenyl)methanol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66709，CAS号为 15258-73-8。

2,6-Dichlorobenzoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66919，CAS号为 50-30-6。

4-Chlororesorcinol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66292，CAS号为 95-88-5。

Mefenpyr-diethyl is an herbicide safener, which protects crops against herbicide injury.

Extracted from Pharbitis nil (Linn.)Choisy fruit.

(+)- Praeruptorin C extracted from Peucedanum praeruptorum Dunn roots.

Piefeltarraenin ⅠB is extracted from the whole herb of Picriafel-terrae Lour.

Pyroglutamylhistidine is a dipeptide.

N6-Succinyllysine is a bioactive chemical.

Ophiocarpine is a protoberberine alkaloid.

Rivanicline hemioxalate (RJR-2403 hemioxalate; (E)-Metanicotine hemioxalate) 是一种神经元烟碱受体 (neuronal nicotinic receptor) 激动剂，对 α4β2 亚型有高度选择性(Ki= 26 nM)，比对于 α7 受体的选择性高1000倍(Ki=3.6 μM)。

Risperidone E-oxime is an impurity of Risperidone, a serotonin 5-HT2 receptor blocker, P-glycoprotein inhibitor, and potent dopamine D2 receptor antagonist (Kis of 4.8 and 5.9 nM for 5-HT2A and dopamine D2 receptors, respectively).

Dibenzylideneacetone is a synthetic curcumin analog. It leads to apoptotic cell death in Leishmania donovani.

Aspirin DL-lysine is a non-steroidal anti-inflammatory drug. It also may inhibit cancer growth. Aspirin DL-lysine is a water-soluble, injectable aspirin derivative.

4,5,6,7-Tetrabromo-1H-benzimidazole 是一种酪蛋白激酶 2(CK2)的选择性和 ATP 竞争性抑制剂。

Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50 = 13 μM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50 = 1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s = 34.3, 47, and 37.2 μg/ml, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50 = 0.84 μg/ml) and increases survival of P. densiflora trees inoculated with B. xylophilus.