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Antibiotic
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Antibacterial
Antibiotic
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Antifungal
Beta-lactamase
CCR
EBV
Enterovirus
GluCls
HBV
HCV Protease
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Antibiotic
Antibiotic
抗生素是一种对细菌有活性的抗菌物质,是对抗细菌感染的最重要的抗菌剂。抗生素药物被广泛用于治疗和预防此类感染。它们可以杀死或抑制细菌的生长。少数抗生素也具有抗原生动物活性。
HIT219599977
Cinerubin R
TN10103
147657-35-0
Cinerubin R 对抗革兰氏阳性菌有活性,并能抑制肿瘤细胞,其对多药耐药(MDR)细胞的抑制效果与普通细胞一致。
Antibacterial
Antibiotic
HIT219599988
Ekatetrone
TN10119
12794-19-3
Ekatetrone 对革兰氏阳性菌和阴性菌表现出活性,特别是对结核分枝杆菌的抑制作用显著。
Antibacterial
Antibiotic
HIT219600048
Phenelfamycins D
TN10167
118498-94-5
Phenelfamycins D (芬纳霉素D) 是一种抗生素,存在于紫黑链霉菌Streptomyces violaceoniger AB 9991-80 和 AB 1047T-33 菌株中,其所有组分均对革兰氏阳性菌表现出活性。
Antibacterial
Antibiotic
HIT219600076
Cystothiazole A
TN10190
207399-36-8
Cystothiazole A 具有抗真菌活性,可抑制白色念珠菌、酿酒酵母和烟曲霉菌,其最低抑制浓度(MIC)分别为 0.4 μg/mL、0.1 μg/mL 和 1.6 μg/mL;同时对人类肿瘤细胞如 HPT-116 和 K562 细胞也显示出抑制活性,MIC 分别为 130 ng/mL 和 110 ng/mL;它不具有抗菌作用。
Antibiotic
Antifungal
HIT219600072
Gilvocarcin E
TN10187
80937-34-4
Gilvocarcin E 对革兰氏阳性菌表现出抗菌活性,并能抑制肉瘤 180 以及 P388 白血病细胞的生长。
Antibacterial
Antibiotic
HIT219600085
γ-Chloronorvaline
TN10203
76265-38-8
γ-Chloronorvaline 在合成培养基中对铜绿假单胞菌、沙雷氏菌、肺炎克雷伯菌及枯草芽孢杆菌表现出抗活性,但对大肠杆菌无效。
Antibacterial
Antibiotic
HIT219599974
Chandrananimycin C
TN10112
664355-11-7
Chandrananimycin C 具有抗毛霉菌活性,并对肿瘤细胞 CCL HT29、MFXF 529L、MACL McF-7 等显示出抑制作用。
Antibiotic
Antifungal
HIT214317507
Desacetylcephalothin sodium
T23980
5547-29-5
Deacetylcephalothin Sodium Salt is an impurity in the synthesis of Cefalonium. It used as a long-acting intramammary cerate for the infusion of dairy cows.
Antibiotic
Others
HIT214317699
Paldimycin A
T24589
101411-70-5
Paldimycin A is a semi-synthetic antibiotic from Streptomyces paulus.
Antibacterial
Antibiotic
Others
HIT214318327
Capoamycin
T26945
97937-29-6
Capoamycin is an insotatracine antibiotic investigated for anti tumor properties.
Antibacterial
Antibiotic
Antifungal
Others
HIT212712342
Cephamycin C
T26980
38429-35-5
Cephamycin C (CepC) is a nontoxic β-lactam antibiotic. CepC stands out from other cephalosporins for its greater resistance to β-lactamases.
Antibacterial
Antibiotic
Others
HIT214319167
Cafamycin
T30685
112303-17-0
Cafamycin is a bioactive chemical.
Antibacterial
Antibiotic
Others
HIT212716149
Formycin B
T31852
13877-76-4
Formycin B is a model nucleoside analog.
Antibiotic
Others
Parasite
HIT212690398
Polymyxin B2
T25971
34503-87-2
Polymyxin B2 is an antibiotic primarily utilized for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa.
Antibacterial
Antibiotic
Others
HIT214318235
AA 57
T26492
68026-87-9
AA 57 is an antibiotic.
Antibiotic
Others
HIT214318556
Mirosamicin
T28046
73684-69-2
Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.
Antibacterial
Antibiotic
Others
HIT214318597
Pacidamycin I
T28288
121264-05-9
Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly.
Antibacterial
Antibiotic
Others
HIT214318512
LY 186826
T27886
126165-79-5
LY 186826 is an antibacterial agent with bicyclic pyrazolidinone properties.
Antibiotic
Others
HIT214319705
Lavendomycin
T32607
82987-09-5
Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.
Antibacterial
Antibiotic
Others
HIT214320749
Deethylindanomycin
T35731
106803-22-9
Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg/ml, respectively). It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg/g in the diet. Deethylindanomycin acts as an ionophore in lipid bilayer membranes and is more selective for potassium ions than calcium, magnesium, and sodium ions. It induces histamine release from rodent mast cells and human basophils in vitro in a calcium-dependent manner.
Antibacterial
Antibiotic
Others
Parasite
HIT212039071
Platensimycin
T35634
835876-32-9
Platensimycin (PTM) is an antibiotic produced by S. platensis that inhibits Gram-positve bacteria by selectively inhibiting cellular lipid biosynthesis (IC50 = 0.1 μM). It targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s = 48 and 160 nM for S. aureus and E. coli enzymes, respectively). By specifically targeting fatty acid synthesis in bacteria, PTM is thought to be a promising agent for overcoming antibiotic resistance. PTM is also a selective inhibitor of the mammalian fatty acid synthase and has been shown to reduce liver triglyceride levels and to improve insulin sensitivity in a diabetic mouse model after an oral dose of 30 mg/kg.
Antibacterial
Antibiotic
Others
HIT214318114
Candicidin D
T25203
39372-30-0
Candicidin D is an antifungal agent isolated from Streptomyces griseus.
Antibiotic
Antifungal
Others
HIT212711579
Candicidin
T25202
1403-17-4
Candicidin is an antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topically in candidiasis. The antibiotic is composed of candicidins A, B, C, and D, of which D is the major component.
Antibacterial
Antibiotic
Antifungal
Others
HIT214318128
Althiomycin
T25060
12656-40-5
Althiomycin is an antibiotic.
Antibiotic
Others
HIT214318162
Linogliride
T25739
75358-37-1
Linogliride 是一种基于胍的胰岛素分泌抑制剂,也是 pirogliride 的结构类似物,具有降血糖活性。它可以阻断胰腺β细胞膜上对 ATP 敏感的钾通道,从而刺激胰岛素分泌并改善葡萄糖耐受性。
Antibiotic
Others
HIT214318153
Lincomycin-B
T25732
2520-24-3
Lincomycin-B is a lincosamide antibiotic isolated from the actinomycete Streptomyces lincolnensis.
Antibiotic
Others
HIT212711261
Laidlomycin
T25602
56283-74-0
Laidlomycin, a polyether, polycyclic, monocarboxylic acid, possesses inhibitory activity against various Mycoplasma species, especially Acholeplasma laidlawii.
Antibacterial
Antibiotic
Others
HIT214317962
Laidlomycin phenylcarbamate
T25603
101191-83-7
Laidlomycin phenylcarbamate is a semi-synthetic polyether antibiotic.
Antibiotic
Others
Parasite
HIT214317761
Hypeptin
T25514
124883-38-1
Hypeptin is an antibiotic agent from Pseudomonas sp.
Antibacterial
Antibiotic
Others
HIT212522261
Dehydrogriseofulvin
T124964
3573-90-8
Dehydrogriseofulvin 是一种天然化合物,可作为天然产物对照品,其 CAS 号为 3573-90-8。
Antibiotic
Antifungal
Others
HIT213887977
Tetromycin C5
T125394
205433-86-9
Tetromycin C5 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125394,CAS号为 205433-86-9。
Antibacterial
Antibiotic
Others
HIT213887720
Helvolinic acid
T126540
10072-61-4
Helvolinic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126540,CAS号为 10072-61-4。
Antibacterial
Antibiotic
Others
HIT105435642
Dechlorogriseofulvin
T124937
3680-32-8
Dechlorogriseofulvin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124937,CAS号为 3680-32-8。
Antibiotic
Antifungal
Others
HIT218903848
Nafithromycin
T200102
1691240-78-4
Nafithromycin (WCK 4873) 作为一种口服抗生素 (antibiotic),主要用于治疗由肺炎链球菌、流感嗜血杆菌、卡他莫拉菌及Methicillin敏感金黄色葡萄球菌引发的社区获得性肺炎。该药物对于大环内酯耐药以及对Telithromycin不敏感的肺炎链球菌,具有较低的最小抑菌浓度(MIC90),仅为0.12 mg/liter。
Antibacterial
Antibiotic
HIT218929780
Antifungal agent 113
T201290
1373311-69-3
Antifungalagent 113 (compound 9a) 表现出针对S. aureus及耐甲氧西林S. aureus的显著抑菌效果,是一种高效的抗真菌和抗细菌化合物。
Antibiotic
Antifungal
HIT219136793
TAN-1057C
T201517
128126-46-5
TAN-1057C具有高效的抗菌特性,能够针对革兰氏阴性菌和革兰氏阳性菌(包括耐Methicillin金黄色葡萄球菌)发挥作用,是一款有效的抗生素。
Antibacterial
Antibiotic
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