Antibiotic

Lankamycin is a macrolide antibiotic from various strains of Streptomyces. It may have significant activity against some Gram positive bacteria.

BO 1165 is an monobactam antibiotic.

Leucinostatin H is a new peptide antibiotic from Paecilomyces lilacinus.

13-Deoxycarminomycin is an antitumor antibiotic.

Polymyxin D2 is a cationic lipopeptide antibiotic against many species of Gram-negative bacteria.

Heptaibin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125107，CAS号为 291311-47-2。

Actinobolin ((+)-Actinobolin) 是一种抗生素，能够通过靶向细菌及真核生物的核糖体抑制蛋白质的合成。它对Mycobacterium smegmatis、Escherichia coli和兔网织红细胞裂解物 (RRL) 的IC50分别为19.2、27.9 和288 μmol/L。

DHFR-IN-22 (Compound 8) 是一种2,4-二氨基嘧啶类DHFR (Dihydrofolate Reductase)抑制剂，具有显著抑制分离的DHFR酶和主要的非结核分枝杆菌 (NTM) 种类（Mycobacterium avium和Mycobacterium abscessus）的活性。该化合物对M. abscessus的IC50为1.1 nM，MIC为1.5 μg/mL，对M. avium的IC50为6.3 nM，MIC为0.1 μg/mL，而对人源DHFR的IC50为2100 nM。DHFR-IN-22 有潜力用于探索抗NTM感染的新策略。

Cefamandole (lithium) 属于第二代广谱头孢菌素类抗生素，具备显著的抗菌效果。在体内代谢过程中，Cefamandole (lithium) 分解并释放游离NMTT，可能引发低凝血酶原血症。

Bekanamycin sulfate is an agent of bioactive chemicals.

L-(+)-Ampicillin is an isomer of Ampicillin. Ampicillin is a β-lactam antibiotic used for treating bacterial infections.

N-Acetylpurinomycin is a selective agonist of CB2 receptor.

Prumycin is an agent of antifungal antibiotic.

Lincophenicol is an Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction inhibitor.

Rosaramicin, a lipid-soluble basic macrolide, is an antibacterial substance similar to erythromycin but with a better activity against Gram-negative bacteria.

Propionylmaridomycin is a macrolide antibiotic.

MB076是一种具有改良血浆稳定性的创新型杂环三唑，能够抑制7种C类Acinetobacter衍生的Cephalosporinases (ADCs)β-内酰胺酶变异体，其Ki小于1 μM。MB076与多种头孢菌素协同作用，恢复pBCSK(−)对多种Cephalosporinases的易感性。

Farinomalein A, 一种从虫生真菌粉质拟青霉 (Paecilomyces farinosus) 分离出的马来酰亚胺，能有效抑制大豆疫霉菌 (Phytophtora sojae)。

Herbarin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5793，CAS号为 36379-67-6。

Nystatin A1, 一种从链霉菌Streptomyces noursei中分离的多烯大环内酯类抗真菌抗生素 (antibiotic)，它通过与真菌细胞膜上的麦角固醇结合，提高细胞膜透性，引起细胞内容物外泄，从而抑制真菌的生长与繁殖。

Ansamitocin P-3 (GMP)是 Ansamitocin P-3 的 GMP 级别试剂。Ansamitocin P-3 是一种微管抑制剂，对微管蛋白聚合的 IC50 为 3.4 μM。

Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.

Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH.

Cephradine sodium is the salt form of Cephradine (free base), a semi-synthetic cephalosporin antibiotic. Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cefradin may interfere with autolysin inhibitors.

Oxanosine is an analog of guanosine that has been found in S. capreolus and has diverse biological activities, including antibacterial, antiviral, and anticancer properties. It is active against a variety of bacteria, including S. flexneri, P. mirabilis, and E. coli (MICs = 6.25, 12.5, 25 µg/ml, respectively, on peptone, but not nutrient, agar). Oxanosine inhibits replication of the HIV-1 strain IIIb in infected CEM and U937, but not H9, cells (EC50s = 7, 27, and >500 µg/ml, respectively). It also inhibits the growth of HeLa human cervical cancer cells (IC50 = 32 µg/ml) and reduces tumor growth in a murine L1210 lymphocytic leukemia model.

Cefmenoxime sodium is the ssalt form of Cefmenoxime (free base), a cephalosporin antibiotic administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms. It is a potent inhibitor of Enterobacteriaceae, and is resistant to beta-lactamase-initiated hydrolysis. The drug has a high success rate against many types of infection.

Kalafungin antimicrobial agent that is inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacteria.

Demethyl bleomycin A2 是Bleomycin 的同源物。Demethyl bleomycin A2 的 DNA 裂解对5-Methylcytidine 不敏感。

Pezulepistat 是一种大环广谱抗生素，用于研究其对革兰氏阴性细菌感染等微生物感染的影响。

Talisomycin A (Tallysomycin A) 是一种用于抗肿瘤的抗生素复合物。

Monamycin IV 是一种酯肽抗生素，针对革兰氏阳性菌展现出活性。

Antibacterialagent 285 (Compound 3) 是一种头孢类抗生素，具有对革兰氏阴性菌的显著抗菌活性。其对碳青霉烯类耐药的Acinetobacter baumannii (CRAB)、Klebsiella pneumoniae (CRE) 和Pseudomonas aeruginosa (CRPA) 的最低抑制浓度分别为0.125-0.5、0.125-0.5和0.125-2 μg/mL。Antibacterialagent 285 可用于研究细菌感染，如复杂性尿路感染 (cUTI) 和肾脏感染。

Pneumocandin A3 是一种脂肽抗生素，表现出显著的抗念珠菌活性，能够在体外抑制 1,3 β-D-葡聚糖合成，其IC50范围为 0.07-0.5 μg/mL。

Fluvirucin A2 是一种新型抗生素，对甲型流感病毒具有良好的抑制效果。

Oudermansin B 是一种针对真菌的抗生素，其通过抑制蛋白质、RNA 和 DNA 的合成来发挥作用。

Micacocidin C 是抗生素，对支原体种展现出极佳活性。