Antibiotic

Plicacetin 是一种可以从链霉菌放线菌的发酵液中提取的抗生素，其晶体结构与Amicetin和Bamicetin相似。

Oritavancin is a novel semisynthetic glycopeptide antibiotics. On August 6, 2014, the FDA approved oritavancin for treatment of skin infections. Oritavancin possesses potent and rapid bactericidal activity in vitro against a broad spectrum of both resistant and susceptible Gram-positive bacteria, including Staphylococcus aureus, MRSA, enterococci, and streptococci.

Dapdiamide A 是一种抗生素，发现于 Pantoea agglomerans CU0119 菌株中，具备抑菌活性，可应用于抗感染领域的研究。

Alnumycin 是一种萘醌类抗生素 (antibiotic)，针对革兰氏阳性菌表现出窄谱抗菌活性，并抑制 K562 人类白血病细胞的生长，IC50为 0.53 μg/mL。

Arylomycin B2 是一种抗生素 (antibiotic) 和高效信号肽酶 I (SPase I) 抑制剂，具备抗革兰氏阳性菌的活性。

Vineomycin A1 (OS-4742 A1) 是一种抗革兰氏阳性菌的抗生素，来源于Streptomyces matensissubsp.vineus。此外，Vineomycin A1 在小鼠实验中展现了抗肿瘤活性，并有望应用于皮肤纤维化的研究。

Arylomycin A5，一种脂六肽抗生素 (antibiotic)，专用于对抗革兰氏阳性菌。

Actinoplanone A 是一种多环黄酮类antibiotic，具有显著的抗菌活性，能够有效抑制细菌和稻瘟病菌。此外，Actinoplanone A 对多种肿瘤细胞表现出细胞毒性，并抑制DNA合成。

Arylomycin A4 是一种用于对抗革兰氏阳性菌的脂六肽抗生素 (antibiotic)。

Cladospirone bisepoxide 是一种从真菌培养物中分离出来的代谢物。Cladospirone bisepoxide 对几种细菌和真菌表现出选择性抗生素活性，并在低浓度下抑制Lepidium sativum 萌发。

Thiomarinol A (4-Hydroxythiomarinol C) 是一种有效的抗生素。Thiomarinol A 是二硫代吡咯酮和海藻酸的混合物。Thiomarinol A 显示出抗菌活性。Thiomarinol A 以剂量依赖性方式抑制 MRSA IleRS，Kiapp 值为 19 nM。

Kalimantacin A是具有针对葡萄球菌（包括耐甲氧西林金黄色葡萄球菌）抗菌活性的有效抗生素。

Monascorubrin 是一种从红曲菌菌丝体中纯化获得的化合物，对枯草芽孢杆菌和拟假丝酵母显示出显著的抗生素活性。

Rubradirin is an antibiotic with a complex chemical structure that is active vs. methicillin resistant staphylococci. It is a selective enzymatic peptide initiation inhibitor.

Leucinostatin B is a peptide antibiotic from Paecilomyces lilacinus A-267.

Surgumycin is a carbonyl-conjugated pentaenic antibiotic.

Septacidin represents a group of l-eptopyranoses including nucleoside antibiotics with antitumor, antifungal, and pain-relief activities.

Frenolicin B 是一种抗生素。

Piampicillin Hydrochloride is a Hydrochloride form of an oral active ampicillin new spray with antimicrobial activity.

(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.

Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses.

Primidolol is a beta adrenergic receptor antagonist and antihypertensive agent.

Elmycin D, 从Streptomyces cellulosae ssp. griseoincarnatus中提取的一种抗生素，具有显著的生物活性。

Arborcandin B 是一种1,3-β-葡聚糖合酶抑制剂，用作抗真菌抗生素。其对白色念珠菌 (C. albicans) 的IC50值为0.30 μg/mL，对烟曲霉 (A. fumigatus) 的IC50值为0.025 μg/mL，并对念珠菌属的MIC范围为2-4 μg/mL。

Leucomycin A4 is a macrolide antibiotic that has been found in S. kitasatoensis. It is active against a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 μg/ml, respectively).

Antibiotic tan-592B is an antibiotic agent.

Isochlortetracycline 是广谱抗生素金霉素降解的无活性碱性产物。

Bromhexine is an expectorant/mucolytic agent which can be used in the treatment of respiratory disorders associated with excessive mucus or viscid.

Alahopcin is a new dipeptide antibiotic generated by Streptomyces albulus subsp. ochragerus subsp. nov.

Omiganan is a cationic antimicrobial peptide with activity against both gram-positive and gram-negative bacteria, as well as Candida spp. isolates. This compound, serving as an analogue of indolicidin, is utilized for research purposes related to alcohol nose and acne.

PD 116152 is a highly substituted phenazine with antitumor activity isolated from the culture broth of a Streptomyces sp. The antitumor activity versus murine P388 leukemia is T/C 149. PD 116152 is selectively active versus the bacterium Streptococcus pne

Kapurimycin A2 is an antitumor antibiotics.

MT0703为含有1,5-二羟基-4-吡啶酮-2-羰基基团的氨基噻唑基甘氨酰头孢菌素，展现出对假单胞菌的优异抗菌性能。

DRF-8417，一种氧杂唑啉酮类抗生素，对革兰氏阳性菌及革兰氏阴性苛养菌展现出抑制活性。该化合物对革兰氏阳性病原体的MIC50和MIC90值范围为0.06-1 mg/L。

Destomycin A 是一种具备多重生物活性的氨基糖苷类抗生素，能有效对抗革兰氏阳性菌及革兰氏阴性菌，同时具有抗真菌和驱虫的特性。此外，Destomycin A 可抑制 Escherichia coli 细胞中的多肽合成，并能激活动物组织内的腺苷酸环化酶。