Others

MTHFD2-IN-3 (compound 10) 是一种有效的亚甲基四氢叶酸脱氢酶 (MTHFD2) 抑制剂。

2'-beta-C-Ethynyluridine is a Nucleoside Derivative - 2'-Modified nucleoside.

TPGS-750-M是一种环境友好的两亲性表面活性剂，由外消旋α-生育酚、MPEG-750和琥珀酸组成，可用于水中金属催化的交叉偶联反应。

Vin-C01 可用于研究Ⅱ型糖尿病，是胰腺 β 细胞的有效保护剂 (EC 50 = 0.22 μM)。Vin-C01 保护 β 细胞免受 STZ 诱导的细胞凋亡，并有效促进 β 细胞存活。

Dermaseptin-S3为源自青蛙皮肤的抗菌肽，具备抗丝状真菌活性。

LY487379是一种选择性的人类 mGluR2 阳性异生调节剂（PAM）。LY487379 可提高谷氨酸刺激的 [35 S] GTPγS 结合，作用于 mGlu2 受体 (EC50: 1.7 μM) 和 mGlu3 受体 (EC50>10 μM)。LY487379 在大鼠模型中促使认知的灵活性，并诱导行为抑制。LY487379 能够用于研究精神分裂症。

PI3Kδ/γ-IN-2 是有效的、口服生物利用度高的 PI3Kδ (IC50: 1 nM) 和 PI3Kγ (IC50: 4.3 nM) 双重抑制剂，具有潜力用于抗 B 细胞恶性肿瘤的研究。

Antifungal agent 54 (compound A05) 是一种抗氟康唑 耐药菌株的强效抗真菌剂。Antifungal agent 54 比咪康唑 更有效。Antifungal agent 54 抑制白色念珠菌的 MIC 值为 0.25-1 μg/mL。

GSK040 是一种有效和具有选择性的BETBD2抑制剂，pIC50值为 8.3。GSK040 对 BETBD2的选择性比 BETBD1(pIC50=4.6) 高 5000 倍。GSK040 可用于肿瘤学和免疫学疾病的研究。该化合物的粉末形式不稳定，建议选择其他盐形式产品。

Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides

HER2-IN-8 是 HER-2 抑制剂，能够用于癌症和炎症相关疾病的研究。

Antiviral agent 20 (Compound 17b) 是一种 Zika 病毒的选择性抑制剂 (EC50: 4.5 μM)，表现出低细胞毒性。

fluorescent ligand that binds to the α4β1 integrin (VLA-4)

ZLc-002 是一种选择性的 nNOS-Capon 偶联小分子抑制剂。ZLc-002 抑制炎症和化疗引起的神经性疼痛。ZLc-002 可用于焦虑和炎症研究。

Sulisobenzone (Sungard) 是防晒霜的成分，能够保护皮肤，使其免于受UVB 和短波紫外线UVA 的伤害。

KRAS inhibitor-3，一种高效KRAS抑制剂，具有强大的亲和力，能够与野生型及致癌型KRAS突变体紧密结合（KD值：KRAS WT为0.28 μM，KRAS G12C为0.63 μM，KRAS G12D为0.37 μM，KRAS Q61H为0.74 μM）。该化合物还能干扰KRAS与Raf之间的相互作用。

Dermabond (2-Octyl cyanoacrylate) 是一种常用于伤口或手术切口闭合的组织粘合剂，具有抗菌活性，可用于研究伤口愈合。

Abaloparatide acetate(247062-33-5 free base) 是一种甲状旁腺激素受体 1 PTHR1 类似物，是 PTHR1 信号通路的有效和选择性激活剂。

Melittin (C-Term Cysteine labeled) TFA 是有细胞毒性蜂毒肽蜂毒肽 melittin， 在 C 端有一个半胱氨酸残基。Melittin (C-Term Cysteine labeled) TFA 可用于膜裂解聚合物的合成。

3'-Sialyllactose (3'-SL) 是一种益生元，具有维持免疫稳态，发挥抗炎和抗关节炎的作用。3'-Sialyllactose 是毒性等级低的普通碳水化合物，可用于炎症的研究。

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker compound employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.

TPα and TPβ are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPβ is believed to be responsible for vascular endothelial growth factor-induced endothelial cell differentiation and migration whereas TPα appears to be the predominant isoform expressed in platelets. CAY10535 is a TP receptor antagonist that shows ~20-fold selectivity for TPβ (IC50 = 99 nM) relative to TPα (IC50 = 1,970 nM) in the inhibition of U46619-mediated Ca2+ mobilization. This compound exhibits relatively poor activity on platelets (IC50 = 985 nM) when inhibiting U-46619-induced platelet aggregation.

Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.

Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that the lack of antitumor efficacy seen with systemic administration of AJ is likely due to its sh

Obafistat 是醛酮还原酶 AKR1C3 的有效抑制剂，抑制人 AKR1C3 的IC50为 1.2 nM。

TN1 是一种有效的胎儿型血红蛋白 (HbF) 诱导剂。

Torcitabine is useful against the hepatitis B virus.

Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 may be useful in the treatment of patients with thrombocytopenia. Avatrombopag was first approved in 2018.

3-Methyldihydrofuran-2,5-dione是一种呋喃衍生物，广泛应用于生物化学实验和药物合成研究。

4-Chlorophenylguanidine hydrochloride 是一种有效的尿激酶选择性抑制剂。

IL-1β-IN-2为大麻酚衍生物，该化合物作为IL-1β抑制剂表现出优良效力，兼具抗炎及镇痛特性。

HS-PEG5-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

T 82 is an antagonist of 5-HT3 and inhibitor of acetylcholinesterase (AChE) and used for the treatment of Alzheimer's Disease.

BPN-14136 是一种高效的视黄醇结合蛋白 4（RBP4）拮抗剂，用于视黄类物质转运及代谢性疾病的作用机制研究。BPN-14136 主要应用于 RBP4 驱动的病理生理过程研究，尤其是在胰岛素抵抗和代谢性疾病模型中的相关研究。

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a Fluoro-modified nucleoside; Halo-nucleoside; Arabino-nucleoside.