Antibiotic

6-Deoxy-8-O-methylrabelomycin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126278，CAS号为 117620-87-8。

Angolamycin是一种大环内酯类抗生素 (antibiotic)，对革兰氏阳性菌有效。

Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.

Antibiotic JI 20A is a bioactive chemical.

Kapurimycin A1 is an antitumor antibiotic produced by Streptomyces.

Paldimycin B is a semi-synthetic antibiotic.

Bacilysin possesses antibactirial activity.

Amythiamicin B is a novel antimicrobial antibiotic.

Albothricin is a streptothricin antibiotic.

Aldgamycin G is a Macrolide antibiotic against Gram-positive bacteria isolated from Streptomyces avidinii.

Aldgamycin E is a neutral macrolide antibiotic agent from culture filtrates of Streptomyces lavendulae. Methanolysis produces methyl algarosides A & B.

A 25794 is an antibiotic with possible antidepressant properties.

Cefluprenam is a a cephalosporin type antibacterial agent.

PD 116779 is a new antitumor antibiotic in the class os benz[a]anthraquinone.

Fortimicin C is a bioactive chemical.

Hatomamicin is a biochemical.

Kidamycin, obtained from Streptomyces phaeoverticillatus strains, can interfere with RNA synthesis.

Levorin A0 is a Levorin component.

Valanimycin is a biochemical.

Burnettramic acid A is a fungal metabolite originally isolated fromA. burnettiithat has diverse biological activities.1It is active againstB. subtilis,S. aureus,C. albicans, andS. cerevisiae(IC50s = 2.3, 5.9, 0.5, and 0.2 μg/ml, respectively). Burnettramic acid A is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 13.8 and >100 μg/ml, respectively). 1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettiiOrg. Lett.21(5)1287-1291(2019)

2',3'-Dideoxy-5-iodocytidine, a chemical compound, is employed in gene sequencing and functions as an antibiotic. It exhibits significant efficacy specifically against Mycobacterium.

Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin inhibits growth of B. subtilis (MIC = 0.05 μg/ml) and induces efflux of potassium ions from B. subtilis without affecting Na+/K+-ATPase activity. It decreases the synthesis of protein, RNA, and DNA in B. subtilis when used at a concentration of 0.05 μg/ml. It inhibits the growth of B. halodurans (MIC = 10 ng/ml) and inhibits the futalosine pathway of menaquinone synthesis in B. halodurans. Boromycin (3.4 nM) reverses bleomycin-induced cell cycle arrest at the G2 phase in Jurkat cells. It inhibits replication of the HIV-1 strains LAV-1 and RF and the HIV-2 strain LAV-2 in MT-4 cells (IC50s = 0.008, 0.11, and 0.007 μM, respectively). It also inhibits replication of a clinical isolate of HIV-1, strain KK-1, in MT-4 cells and peripheral blood mononuclear cells (PBMCs; IC50s = 0.14 and <0.1 μM, respectively).

Saccharocarcin B 是从放线菌 Saccharothrix aerocolongenes subsp.antibiotica SCC1886 的发酵液中分离出来的。

Anguinomycin A is an antibiotic first isolated from a Streptomyces sp. and analog of leptomycin B that is highly cytotoxic to mouse P388 leukemia cells in vitro (IC50 = 0.1-0.2 ng/ml). It also demonstrates antitumor activity at 62.5 μg/kg/day against Lewis lung carcinoma in mice.

TPU-0037A is an antibiotic and a congener of lydicamycin . It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs = 1.56-12.5 μg/ml), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs = >50 μg/ml).

Mycalolide-B is a marine sponge-derived compound that functions as a selective inhibitor of actomyosin ATPase. It effectively hinders ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+.

Quindecamine acetate，一种Quinaldine的衍生物，展现出了抗真菌 (antifungal) 活性。

Antibacterialagent 221 （compound 3k）针对MRSA（革兰氏阳性耐甲氧西林金黄色葡萄球菌）表现出高效的抑制作用。此外，该化合物在人类LO2及HepG2细胞系中展示了显著的细胞毒性。

Irumamycin是一种天然的20元大环内酯类抗生素(antibiotic)，在体外对某些植物病原真菌和锥虫具有活性。

Nikkomycin Lx 是从Streptomyces tendae TU901中提取的抗生素，对念珠菌具有抑制作用，可用于相关研究。

Aibellin是一种抗生素（antibiotic），为调节瘤胃发酵提供了有效的解决方案。

Adustin是一种抗真菌抗生素 (antibiotic) 和多肽，具有翻译抑制活性。在无细胞兔网织红细胞裂解物系统中，Adustin抑制翻译的IC50为0.34 μM。

Bagougeramine B 是一种口服活性的核苷类抗生素 (antibiotic)，具有显著的抗菌活性，来源于Bacillus circulans。它能够抑制革兰氏阳性和革兰氏阴性细菌以及部分真菌的生长。

Aranochlor A 是一种在 Pseudoarachniotus roseus (HIL Y-30499) 中发现的抗生素 (antibiotic)，具有抗菌和抗真菌活性。

Arborcandin A 是一种1,3-β-葡聚糖合酶抑制剂，用作抗真菌抗生素。其对白色念珠菌 (C. albicans) 和烟曲霉 (A. fumigatus) 的IC50分别为0.25 μg/mL和0.05 μg/mL，对念珠菌属的MIC值在4-8 μg/mL之间。

Andrimid 是一种伪肽抗生素 (antibiotic)，属于聚酮-非核糖体肽杂化产物 (PK-NRP)。它通过阻断细菌乙酰辅酶 A 羧化酶 (ACC) 的羧基转移反应，从而抑制细菌脂肪酸的生物合成。Andrimid 可在生物医药和生物农业中广泛应用。