Others

PI3Kγ inhibitor 4 是一种选择性的、有效的、口服具有活力的 PI3Kγ 抑制剂 (IC50: 40 nM)。PI3Kγ inhibitor 4 对 PI3Kγ 的选择性是 α 亚型的~7 倍、是 β 亚型的 43 倍、是 δ 亚型的 18 倍。PI3Kγ inhibitor 4 能够用于研究气道炎症。

PHA-543613 hydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.

Sunepitron is a combined α2-adrenergic receptor antagonist and 5-HT1A receptor agonist.

Azide-PEG7-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

PXYC2 是一种核糖体蛋白 S1 (RpsA) 拮抗剂，对 RpsA-CTD 和 RpsA-CTD Δ438A 的 Kd 分别为 6.35 和 5.11 μM。在结核分枝杆菌 (Mtb)转译过程中，RpsA 发挥重要作用。

MitoTam iodide, hydriodide is an inhibitor of electron transport chain (ETC)

Gamma-Glutamylarginine是一种天然的γ-谷氨酸寡肽，是由谷氨酸和精氨酸组成的二肽。

2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.

Mal-NH-PEG2-CH2CH2COOPFP ester is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

BTI-A-404 is a potent and selective competitive inverse agonist of human GPR43.

1,3-dihydroxy-4-methoxy-10-methylacridin-9-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2491，CAS号为 1189362-86-4。

Levamisole是一种片段化合物。

ERβ receptor agonist

N-tert-Butylisopropylamine是一种仲胺，广泛应用于生物化学实验和药物合成研究。

TrxR-IN-3 (Compound 2c) 是TrxR 的有效抑制剂。TrxR-IN-3 对五种人类癌细胞系表现出强大的抗增殖活性，特别是对乳腺肿瘤细胞。TrxR-IN-3 增加 ROS 水平并通过调节乳腺癌细胞中细胞凋亡相关蛋白的表达导致明显的细胞凋亡。TrxR-IN-3 还通过促进 LC3-II 和 Beclin-1 的表达并减少 LC3-I 和 p62 蛋白的表达，来触发自噬体和自溶酶体的形成。

Rusalatide acetate (TP508 amide acetate) 是一种再生肽，可诱导干细胞再生修复，保护隐窝完整性，减缓辐照引起的胃肠道损伤。

CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.

2'-Deoxy-5,N4-dimethylcytidine is a Nucleoside Derivative - N-Methylated nucleoside.

HIV-1 inhibitor-45 是 HIV-1 RNase H 的有效抑制剂 (IC50: 0.067 μM)，具有抗病毒效果。

K 579 is a dipeptidyl peptidase IV inhibitor.

7-Ketocholesterol 是胆固醇的代谢物。

HDAC-IN-49 是一种有效的非选择性 HDAC(HDAC) 抑制剂，对 HDAC1、HDAC2、HDAC3、HDAC4 和 HDAC6的 IC50分别为 13 nM、14 nM、21 nM、1880 nM 和 10 nM 。HDAC-IN-49 表现出显着的抗白血病活性， 但对健康细胞具有低细胞毒性。

PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).

Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.

A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD) and methionine-choline deficient diet (MCD).

Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulation and the resultant decrease of Ca

(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5 double bond. (±)4(5)-DiHDPA lactone is a derivative of docosahexaenoic acid that is analogous to (±)5(6)-DiHET lactone. It is the 1,4 cyclic ester derived from (±)4(5)-DiHDPA, which is produced by epoxidation of DHA at the α-4 double bond. Its biological activity is unknown.

diuretic and antihypertensive

IACS-8803 is a potent cyclic dinucleotide STING agonist that exhibits strong systemic antitumor efficacy.

Myristoyl Ethanolamide是一种内源性大麻素类化合物，属于脂肪酰乙醇胺家族。N-Myristoylethanolamine在神经系统中具有一定的生理活性，通常在大鼠脑脊液中检测到低水平。

5-Amino-8-hydroxyquinoline dihydrochloride已被用于合成以下化合物：5-乙酰氨基-8-羟基喹啉盐酸盐、5-(对甲苯磺酰亚胺基)喹啉-8-酮以及通过氯化铁介导的氧化反应制备5,8-喹啉半醌。

Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc

Herkinorin is an opioid analgesic and an analogue of the natural product Salvinorin A. herkinorin is a μ-opioid agonist with more than 100x higher μ-opioid affinity and 50x lower κ-opioid affinity compared to Salvinorin A. Herkinorin is a semi-synthetic c

HBV-IN-6 是一种 HBV 的有效抑制剂 (EC50: 5 nM)。

GluR5-subunit containing kainate receptor antagonist

KM02894 是一种谷氨酸释放抑制剂。癌细胞释放高水平的谷氨酸，能够破坏正常的骨转换，这可能导致癌症引起的骨痛。KM02894 可用于研究肿瘤相关疾病。