Others

JNJ-10181457 (hydrochloride) 是一种非咪唑类 H3 受体拮抗剂，具有脑渗透和选择性的，可在大鼠额叶皮质内增加 NE 和乙酰胆碱的浓度。可用于神经学相关研究。

NMDA receptor agonist

Protein kinase C (PKC) activator

Propargyl-PEG8-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Isobutyl isovalerate（异丁基异戊酸酯）是一种酯，常用于香料制备、有机合成和生化实验。

L-Methionine-DL-sulfoximine (MSO) 抑制谷氨酰胺合成酶，主要在代谢和形态上影响星形胶质细胞。L-Methionine-DL-sulfoximine 可用于惊厥相关研究。

Coenzyme FO 是辅酶 F420 的合成前体，是 DNA 光解酶的光捕获发色团。

Saphenamycin is an antibiotic from a strain of Streptomyces.

Boc-NH-PEG24-CH2CH2COOH is a polyethylene glycol (PEG)-based linker for PROTAC (Proteolysis-Targeting Chimeras) synthesis[1].

GNF6702 是一种选择性的动质体蛋白酶体 (kinetoplastid proteasome) 抑制剂。GNF6702 对利什曼病、南美锥虫病和人类非洲锥虫病小鼠模型中的寄生虫具有清除作用。

The use of costic acid and other components from the plant Dittrichia viscosa (Greek: aconiza) and related species for the preparation of acaricidal products used against the acari Varroa destructor as parasite of the honey bee.

Jaceidin triacetate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4344，CAS号为 14397-69-4。

Massarilactone H 是一种聚酮化合物，是神经氨酸酶抑制剂，IC50值为 8.18 µM。

1,3-Dilinoleoyl Glycerol (Standard) 是一种可用于分析的标准物质，通常用作 1,3-Dilinoleoyl Glycerol 的研究和分析中参考的标准样品。1,3-Dilinoleoyl glycerol 是一种不饱和二酰基甘油，其在 C-1 和 C-3 位置分别带有亚油酸（18：2）侧链，这种物质在脂质研究中具有重要价值。

Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.

Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker commonly employed for synthesizing PROTACs[1].

5-HT2/5-HT7 receptor antagonist

HSP90-IN-14 (compound 4) 是有效的Hsp90 抑制剂（Kd= 0.26μM）。在MDCK 细胞中，HSP90-IN-14 表现出抗流感病毒活性，抗 A/H3N2、A/H1N1 和 B 型流感病毒的EC50分别为 2.6、3.9 和 17 μM。

NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.

Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.

α-Methyl-trans-cinnamaldehyde是一种不饱和醛，广泛应用于生物化学实验和药物合成研究。

G0507 is a pyrrolopyrimidinedione compound that serves as a potent inhibitor of Escherichia coli growth, effectively inducing the extracytoplasmic σE stress response. It acts as a valuable chemical probe, specifically designed to dissect lipoprotein trafficking in Gram-negative bacteria. Notably, G0507 demonstrates strong inhibitory activity against the LolCDE ABC Transporter.

ERK5-IN-3 是选择性的、有效的 ERK5 (细胞外信号相关激酶 5) 抑制剂 (IC50: 6 nM)。ERK5-IN-3 对 Hela 细胞表现出抗增殖作用 (IC50: 31 nM)。

Olaparib (Standard) 是一种可用于分析的标准物质，通常用作 Olaparib 的研究和分析中参考的标准样品。Olaparib (KU0059436) 是 PARP1/PARP2 的小分子抑制剂 (IC50=5/1 nM)，对 PARP tankyrase-1 的抑制活性较弱 (IC50=1.5 μM)，具有选择性和口服活性。Olaparib 具有自噬和线粒体自噬激活活性。

MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.

RSV-IN-3 (Compound 1) 是呼吸道合胞病毒 (RSV) 和流感病毒 A (IAV) 的双重抑制剂。RSV-IN-3 具有抗 RSV 活性 (EC50=32.70 μM)。

R-(+)-Cotinine ((+)-Cotinine) 是一种尼古丁代谢物，在广泛的药理靶标中缺乏显着活性。R-(+)-Cotinine 可以增强人 α7nAChR 中的 Ach 诱发电流。

Protein kinase G inhibitor-2 具有抗菌、抗病毒和抗肿瘤活性。

Etamivan (Ethamivan) 是口服有活性的呼吸激活剂，常用于研究巴比妥类药物过量与慢性阻塞性肺疾病。

Aldehyde Reactive Probe TFA (ARP TFA) 是一种醛反应探针，用于检测植物 mRNA 中脱碱基位点的水平。

PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficacy in promoting RGC survival. Notably, PB2 exhibits superior permeability compared to TCEP. Serving as a potent reducing agent, PB2 provides robust neuroprotection for RGCs[1].

Alimemazine hemitartrate (Trimeprazine hemitartrate) 是血凝素 (HA)-受体的拮抗剂，也是一种吩噻嗪衍生物，常用作止痒剂。

Imidazol-1-yl-acetic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T67657，CAS号为 22884-10-2。

CFM-5 具有抗惊厥活性，可用于研究癫痫。

FmocNH-PEG4-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tetrahydrocorticosterone (Standard) 是一种可用于分析的标准物质，通常用作 Tetrahydrocorticosterone 的研究和分析中参考的标准样品。Tetrahydrocorticosterone (THB) is a glucocorticoid (GC) that has anti-inflammatory functions. For instance, 5α THB inhibits inflammatory actions by binding to GC receptor. HPLC studies in rat brains have reported that tetrahydrocorticosterone (THB) isomers are differentially distributed in males and females.