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Detomidine is a nonnarcotic, synthetic α2-adrenergic agonist. Detomidine produces dose-dependent sedative and analgesic effects.

Ethyl 2-methyl-1H-pyrrole-3-carboxylate是一种吡咯衍生物，广泛应用于生物化学实验和药物合成研究。

Acid-PEG5-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

VRT-043198 是 VX-765 (Belnacasan) 的活性代谢物，是有效的、选择性的、能透过血脑屏障的caspase-1的抑制剂。VRT-043198 对caspase-1和 caspase-4 的 Ki 值分别为 0.8 nM 和 0.6 nM。

5-Biotinamidopentylazide is a PROTAC linker compound derived from an alkyl chain. This compound finds utility in the synthesis of PROTACs.

Pomalidomide-5-C9-NH2 hydrochloride为E3泛素连接酶cereblon（CRBN）配体，基于Pomalidomide开发，旨在招募cereblon蛋白，能通过linker与蛋白质配体结合，构建PROTAC。

GLP-1R agonist 17，一种表现出极佳激动作用于GLP-1受体的GLP-1受体激动剂，适用于心血管代谢疾病研究。

S-14671 is a 5-HT1A receptor agonist (pKi = 9.3) with high efficacy and exceptional in vivo potency. S-14671 also acts as a 5-HT2A and 5-HT2C receptor antagonist (both are pKi = 7.8).

ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.

Oxaprozin potassium 是具有口服活性的COX 的抑制剂，其对人血小板COX-1 的IC50值为 2.2 μM，对 IL-1 刺激的人类滑膜细胞COX-2的IC50值为 36 μM。Oxaprozin potassium 诱导细胞凋亡。Oxaprozin potassium 还抑制 NF-κB 活化，Oxaprozin potassium 介导的Akt/IKK/NF-κB 通路抑制有助于其抗炎特性。

Tofisopam (Grandaxin) 是2,3-苯二氮卓类化合物，具有抗焦虑活性，可口服。

Atorvastatin acetonide tert-butyl ester, a valuable pharmaceutical intermediate, is used in preparing Atorvastatin salts, an HMG-CoA reductase inhibitor.

9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.

UMB-136 is a bromodomain BRD4 inhibitor that acts by significantly inducing HIV-1 reactivation.

Glycolic acid oxidase inhibitor 1（compound 2 in table 1）是一种乙醇酸氧化酶 (glycolate oxidase) 抑制剂,从而减少肾结石的形成风险。还能够抑制由过敏反应引起的慢反应物质（SRS-A）引起的豚鼠回肠收缩，对过敏性疾病，如哮喘，具有治疗潜力。

Boc-Aminooxy-PEG2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Picilorex is a monoamine reuptake inhibitor, a stimulant as well as a derivate of Pyrrolidine.

3-pyridine toxoflavin 是一种有效的 KDM4C 抑制剂，IC50=19 nM。

Purinostat mesylate 是一种选择性的 HDAC 抑制剂。Purinostat mesylate 能够抑制 I 型和 IIb 型 HDACs (IC50: 0.81-11.5 nM)。Purinostat mesylate 能够影响LAMA84 和 188 BL-2 细胞的细胞周期，并诱导其凋亡，在体内显示出较强的抗白血病效果。Purinostat mesylate 能够用于研究淋巴细胞白血病。

GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of diabetes, hyperlipidemia, non-alcoholic fatty liver, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral infa

1-Octadecene是一种长链烯烃，广泛应用于生物化学实验和药物合成研究。

Diethylamiodarone is the main metabolite of amiodarone in vivo.

Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.2

DL-TBOA ammonium is a potent, non-transportable inhibitor of excitatory amino acid transporters. Its inhibitory effects are demonstrated by IC50 values of 70 μM, 6 μM, and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2, and EAAT3, respectively. Additionally, DL-TBOA ammonium significantly hampers the uptake of [14C]glutamate in COS-1 cell lines expressing human EAAT1 and EAAT2, evident by Ki values of 42 μM and 5.7 μM, respectively. Furthermore, this compound competitively blocks EAAT4 and EAAT5, with Ki values of 4.4 μM and 3.2 μM, respectively.

Chitin synthase inhibitor 3 (compound 2d) 是一种高效的chitin synthase抑制剂，具有0.16 mM的IC50值，并对candida albicans显示出1 μg/mL的MIC，表现出抗真菌活性。

4-Methylthio-2-butanone是一种硫醚酮类化合物，广泛应用于生物化学实验和药物合成研究。

HPK1-IN-34(Compound 143)是一种HPK1(Hematopoietic progenitor kinase 1)抑制剂，IC50< 0.1 μM，可用于研究癌症和免疫。

5-Methylisoxazole是一种含有甲基的异噁唑杂环化合物，广泛应用于生物化学实验和药物合成研究。

Boc-Leu-Gly-Arg-AMC是一种特异性荧光底物，用于酶法检测和定量补体成分C3/C5转化酶、凝血因子Xa及大豆胰蛋白酶样酶活性。Boc-Leu-Gly-Arg-AMC还可被人红细胞分离的高分子量巯基蛋白酶——巨蛋白酶水解，使其成为酶学检测中的多功能工具。

13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified α-linolenic acid.[1] Incubation of soybean seedling biomembranes with soybean LO-2 catalyzes the formation of both 9- and 13-HpOTrE in a molar ratio of 10:1.1 In plants, 13(S)-HpOTrE can be metabolized by the hydroperoxide lyase pathway producing aldehyde and oxoacid fragments, or by the hydroperoxide dehydratase pathway producing jasmonic acid.[2],[3],[4] Treatment of tomato leaves with 13-HpOTrE causes induction of proteinase inhibitors, simulating the normal response to wounding.5 This data suggests that in plants 13(S)-HpOTrE may participate in a lipid-based signalling system initiated by insect and pathogen attack.

2-Methoxypyridine是一种吡啶衍生物，广泛应用于生物化学实验和药物合成研究。

1-Octen-3-yl Acetate是一种酯类化合物，广泛应用于生物化学实验和药物合成研究。

Antifungalagent 67 (compound 9) 是一种抑制念珠菌有效的咪唑类抗真菌剂，其对健康新生大鼠成心肌细胞的 CC50 值为 33.6 μM。

DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite 是一种核苷类似物，在生命科学相关研究中具有广泛的应用。

UBX1325 是一种Bcl-xL 抑制剂，可促进衰老细胞的凋亡 (apoptosis)。UBX1325 是一种有效的抗衰老剂，可用于与年龄相关的眼部疾病的研究，如糖尿病性黄斑水肿 (DME)、年龄相关性黄斑变性 (AMD) 和糖尿病性视网膜病变 (DR)。

化合物17o（IC50: 14.0 nM，NCI-H460）和17p（IC50: 2.9 nM，NCI-H460）与呋喃基团在纳摩尔水平上对各种人类癌细胞系显示出有效的细胞毒性作用。