Others

Boc-N-amido-PEG4-C3-acid is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.

Ro 22-9194 is a class I antiarrhythmic agent. Ro 22-9194 (>=10 μM) caused a concentration-dependent decrease in the maximum upstroke velocity and shortening of action potential duration in guinea-pig ventricular cells.

(R)-Dinotefuran ((R)-MTI-446) 是一种新烟碱类农药，与消旋混合物相比，通过抑制烟碱乙酰胆碱受体 (nAChR) 对典型的吸吮性害虫Aphis gossypii 和Apolygus lucorum 表现出相当的杀虫活性 (1.7-2.4 倍)。(R)-Dinotefuran 具有良好的防治目标害虫的作用，同时减少对蜜蜂的危害。

Tetrahydroellipticine (1,2,3,4-Tetrahydroellipticin)是一种含有吡啶和咔唑的芳香族化合物，可用于有机合成和药物设计。

PI3K/AKT-IN-2 是一种 PI3K 和 AKT 抑制剂。PI3K/AKT-IN-2 阻断上皮-间质转化 (EMT)，诱导细胞凋亡 (apoptosis)。PI3K/AKT-IN-2 抑制微管蛋白 (tubulin) 的聚合。

BI 6015 是肝细胞核因子 4α (HNF4α) 拮抗剂，可抑制已知 HNF4α 靶基因的表达。它利用 HNF4α 拮抗作用，降低胰岛素启动子活性，可用于研究癌症和糖尿病。

Mal-PFP ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

5-Methylurapidil is an alpha1A-adrenoceptor antagonist.

Tos-PEG2-O-Propargyl is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, commonly employed for the synthesis of Thalidomide-O-PEG2-propargyl[1].

14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs of 3.74, 14.97, and 7.49 microM , r

YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.

2-O-Methylcytosine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T64878，CAS号为 3289-47-2。

Pseudolaric acid B β-D-glucoside (Pseudolaric acid B-glucopyranoside) 是一种二萜酸，分离自Pseudolarix kaempferi 中。

Bromo-PEG5-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1]. It is utilized in the construction of PROteolysis TArgeting Chimeras (PROTACs), which are heterobifunctional molecules designed to induce protein degradation.

FUBP1 - in-1, with an IC50 value of 11.0 M, is an effective FUSE binding protein 1 (FUBP1) inhibitor that can interfere with the binding of FUBP1 to its SINGLE-strand target DNA FUSE sequence.

Gomisin L2 is a natural product from Schizandra chinensis BAILL.

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand based on Thalidomide and a linker component commonly utilized in PROTAC technology.

PDE7-IN-3（例2）是一种具有潜在镇痛活性的PDE7磷酸二酯酶抑制剂，可用于探究炎性、神经性、内脏性及伤害性疼痛。

2-Acetyl-6-methylpyridine是一种吡啶衍生物，广泛应用于生物化学实验和药物合成研究。

Isocytidine derivative; fluoro-modified nucleoside

Carbomycin B is an intermediate in the synthesis of Carbomycin. Carbomycin is a macrolite antibiotic complex produced by Stroptomyces halstedii, that is similar to Leucomycin and Erythromycin.

5'-Deoxy-5'-N-(2-chloroethyl)aminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.

5-Methyl-2(5H)-furanone是一种呋喃酮，对多种ASPERGILLUS具有抗真菌活性，可用于生物化学实验和药物合成研究。

Lactyl-CoA是一种酰基辅酶A，其辅酶A的巯基与乳酸的羧基发生了缩合反应，可用于合成乳酸基共聚物的生物材料。

Baxdrostat 是一种醛固酮合成酶抑制剂。

Amygdalin (Laetrile) 是一种植物葡萄糖苷，分离自蔷薇果实的果核中，如杏，桃，杏仁，樱桃和李子。

Tussilagone 是Tussilago farfara 的主要活性成分，具有抗炎作用。它抑制盲肠结扎和穿刺导致脓毒症的小鼠的炎症反应，提高其生存率。它改善葡聚糖硫酸钠诱导的小鼠结肠炎的炎症反应。

INO5042 is an anti-inflammatory agent.

USP1-IN-3 是 USPI 的选择性抑制剂，能够抑制 USPI-UAFI (IC50<30 nM)。USP1-IN-3 可用于研究癌症。

Dual AChE-MAO B-IN-2 是一种有效的、双重的 AChE (IC50: 0.12 μM) 和 MAO B (IC50: 0.01 μM) 抑制剂。Dual AChE-MAO B-IN-2 具有潜力进行阿尔茨海默病的研究。

Wistin 可从 Caragana sinica 根部分离得到，是 PPARα和 PPARγ的激动剂。

GKA-22 is a human glucokinase allosteric activator in the absence of glucose.

Mal-amido-PEG4-TFP ester, a PEG-based PROTAC linker, finds utility in the synthesis of PROTACs[1].

Indacrinone is an investigational diuretic.

SOS1-IN-13 是有效的SOS1抑制剂。SOS1-IN-13抑制 SOS1 和 pERK 的IC50分别为 6.5 nM 和 327 nM。SOS1-IN-13 在抗癌研究中具有一定的价值。