Others

I-A09 is a noncompetitive mPTPB inhibitor.

Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).

SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. It is effective at a final concentra

SQ 30774 is a representative of the imidazole alcohols-a novel class of renin inhibitors.

SQ 27786 is an inhibitor of ACE.

ST7710AA1 is a PARP-1 inhibitor that acts by showing significant in vitro target inhibition and capability to substantially bypass the multidrug resistance mediated by Pgp.

Zuclomiphene is a nonsteroidal selective estrogen receptor modulator (SERM) with triphenylethylene group.

(BrMT)2 is an activator of the Kv1.1 potassium ion channel.

(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.

Promothiocin A is an antibiotic.

R 82150 is an antiviral and a member of the tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepin-2(1H)-thione family.

R(+)-6-Bromo-APB HBr is used as a D1 Dopamine receptor agonist.

RB 101 suppresses enkephalinase and aminopeptidases; biologically cleaved at disulfide to produce inhibitors of both aminopeptidase N and neutral endopeptidase.

Renierone is an antimicrobial metabolite isolated from the marine sponge, Reniera sp.

A 65281 is an antibacterial isothiazoloquinolone and a potent inhibitor of the P4-unknotting reaction. It induces considerable DNA breakage mediated by calf thymus topoisomerase II.

A 80915A is A semi-naphthoquinone antibiotic from Streptomyces aculeolatus. It is a potent inhibitor of gastric (H(+)-K+)-ATPase. Inhibition by A80915A is dependent on the conformation of gastric (H(+)-K+)-ATPase, potassium slows the rate of inhibition by

AB 3217-B is an anti-mite substance isolated from streptomycete strain.

GR 196429, a melatonin receptor agonist, exhibits selectivity for the MT1 subtype. This compound not only promotes sleep and alters circadian rhythms but also stimulates melatonin release in mice.

Rhizocticin A is a potential inhibitor of threonine synthase.

RK-1441A is an antibacteriophage antibiotic related to neothramycin.

RS 30026 is a potent calcium channel agonist.

Rubradirin B has an antibacterial activity similar to rubradirin, but the antibiotic is less active.

NC 1100 is a calcium channel antagonist.

NVP-AAD777 is a specific VEGFR-2 inhibitor.

NSC-12404 is a selective non-lipid LPA2/3 agonist.

Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.

GSK-215083 is a PET radioligand for the 5-HT6 receptor. GSK 215083 is a quinoline based compounds and acts by antagonising the 5-HT6 receptor. GSK-215083 binds to receptors 5-hydroxytrypamine-6 (5HT6) in the striatum and 5-hydroxytryptamine-2A (5HT2A) in

GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.

Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.

SB 201146 is a leukotriene B4 antagonist with high affinity.

Ro 41-1879 is a catechol cephalosporin with antimicrobial activity.

Ro-23-9424 is a dual-action cephalosporin with a fleroxacin esterified at the 3' position and aminothiazolylmethoxyimino-type side chain at the 7 position. Ro-23-9424 has broad and potent antibacterial activity in vitro and in vivo.

RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.

SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.

Sch 202596 is a selective non-peptide antagonist of GAL-1 receptor.

Sch 31828 is an antibiotic from Microbispora.