Others

Ingavirin, a novel inhibitor of the influenza virus reproduction, inhubits the formation of the virus specific hemagglutinin.

Kasugamycin is an antibiotic that acts by binding within the mRNA channel of the 30S subunit and inhibiting protein synthesis.

JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand with tissue-selective activity in rats. JNJ-26146900 binds to the rat AR with a K(i) of 400nM.

HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.

KB-141 is an agonist of thyroid hormone receptor.

BKM-570, a bradykinin antagonist, causes impressive growth inhibition of lung and prostate tumors.

BMS-932481 is a γ-secretase modulator.

ACT-387042 is a Bacterial Topoisomerase Inhibitor, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.

ALRT 1550, a retinoic acid agent (RAR) agonist, is used potentially for the treatment of cervical carcinoma.

Ambazone hydrate has anti-cancer activity.

BFE-55 is derivative of befunolol (a beta-adrenergic partial agonist). BFE-55 interacts with only the high affinity sites in beta-adrenoceptors

BIIL 260 is a leukotriene B4 (BLT1) receptor antagonist with anti-inflammatory activity.

BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.

BIIB-513 is an inhibitor of Na+/H+ exchange.

Binedaline is a selective norepinephrine reuptake inhibitor with Ki value of 25 nM.

Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of the protein from the nucleolus to t

DNS-8254 is a potent and selective Phosphodiesterase 2 (PDE2) inhibitor for the treatment of Memory Disorders (hPDE2a IC50 = 8 nM, Rat Cl-int = 25.6 uL/min/mg). DNS-8254 demonstrated significant memory enhancing effects in a rat model of novel object reco

CCD-3693 is a gamma-aminobutyric acid (GABA) receptor agonist.

AVX-001, a cytosolic phospholipase A2 (cPLA2) inhibitor, is used potentially for the treatment of psoriasis.

BNS is a potent, prolyl-hydroxylase 2 (PHD2)-selective inhibitor.

Bofumustine is a chloroethyl nitrosourea with anti tumor properties.

BX 667 is a P2Y12 receptor antagonist. BX 667 blocks ADP-induced platelet aggregation in human, dog and rat blood with IC50 value of 97, 317 and 3000 nM respectively.

BIBO3304 is a selective NPY Y1 receptor antagonist (IC50 values are 0.38 and 0.72 nM at human and rat receptors respectively). BIBO3304 inhibits NPY- and fasting-induced feeding in vivo following central administration.

Tripalmitolein is a triacylglycerol that contains palmitoleic acid at the sn-1, sn-2, and sn-3 positions. It reduces red blood cell deformability in a concentration-dependent manner in a Reid's filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in the JAK2L mouse model of hepatic steatosis. Tripalmitolein plasma levels are decreased in renal patients before dialysis.

VinSpinIn is a probe for the Spin family proteins.

VMY-2-95 is an α4β2 nicotinic acetylcholine receptors (nAChRs) selective desensitizer.

Viquidacin ( NXL-101) is an oral/intravenous antibiotic that targets Gram-positive bacteria such as MRSA. In 2008, Novexel announced it had discontinued the development of Viquidacin (NXL 101).

X 14547-A is a biochemical product.

WAY 150138 inhibits the herpes simplex virus.

Valinotricin is a minor fungal metabolite.

UCM 549 is a bioactive chemical.

Vedroprevir, also known as GS9451, is a selective hepatitis C virus (HCV) NS3 protease inhibitor in the development of the treatment of genotype 1 (GT1) HCV infection.

Tolypomycin R is a rifamycin derivative.

Sarcinapterin is a coenzyme isolated from Methanosarcina barkeri.

SH-5 是一种AKT抑制剂，通过抑制IκBα激酶激活调节的抗凋亡、增殖和转移基因产物，增强细胞凋亡并抑制侵袭。

Semduramicin sodium is a carboxylic acid ionophore for management of chicken coccidiosis.