Antibiotic

Abierixin 具备显著的抗球虫特性，同时具弱抗菌作用及离子载体活性。

Phoenistatin 是一种物质，其在 3 nM-1000 μM 范围内可使 PA1-1 启动子的基因表达增加三倍以上。

Mureidomycin E 是一种抗生素，而 Mureidomycin C 则具有抗铜绿假单胞菌活性。

Norplicacetin（Norplicacetin）对革兰氏阳性菌和分枝杆菌表现出抗菌活性。

Fluvirucin B4 是一种新型抗生素，对甲型流感病毒有效。

Micacocidin A 是一种抗生素，对支原体菌种表现出极佳活性。

Pneumocandin A1 是一种脂肽类抗生素，具有显著的抗念珠菌活性，能够在体外抑制 1,3 β-D-葡聚糖的合成，其IC50为 0.07-0.5 μg/mL。

Pyloricidin A2 是一种有效的抗生素，由芽孢杆菌属 HC-70 产生，可针对幽门螺杆菌表现出强效的抑菌活性。Pyloricidin A2 对于其他细菌和酵母菌则不具备抑制作用。

Pneumocandin A4 是一种脂肽类抗生素，表现出优异的抗念珠菌性能，能够在体外抑制 1,3 早葡聚糖的合成，其IC50范围为0.07-0.5 μg/mL。

Parvodicin C1 为 Dalbavancin 的中间体。

Antibacterialagent 266 (Compound C5) 是一种有效的植物病原菌抑制剂，通过破坏细菌细胞膜的完整性而起作用，对Xanthomonasoryzaepvoryzae (Xoo) 和X. axonopodispvcitri (Xac) 的EC50值分别为24.1 μg/mL和39.0 μg/mL。Antibacterialagent 266 可用于植物病理学研究以及农业抗菌制剂的开发。

Kapurimycin A2 is an antitumor antibiotics.

Dactylfungins B is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.

Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.

LL D05139(beta) is an novel antitumor antibiotic agent.

Nikkomycin is used as an insecticide.

Lankacidinol A is a metabolite of macrolide antibiotic.

Lankacyclinol A is a Lankacidin antibiotic.

Altromycin E is a new pluramycin-like antibiotic.

Altromycin F is a new pluramycin-like antibiotic.

Piperic acid is a powerful antioxidant and has potent antibacterial properties

Pyrrofolic acid shows high anti-folate biological activity for S. faecalis.

Rubradirin is an antibiotic with a complex chemical structure that is active vs. methicillin resistant staphylococci. It is a selective enzymatic peptide initiation inhibitor.

Spm viii is a derivative of the nucleoside antibiotic spicamycin that has antitumor activity.

A 83016A is a kinamycin-type antibiotic.

Rabelomycin is an angucycline group antibiotic.

RK 1441B is a bacteriophage antibiotic related to neothramycin.

Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.

BK 218 is a novel cephalosporin, which is active against streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrase, but has a higher MIC against penicillin-resistant strains. Bk-218 has dual administration routes and the activity spectrum m

10'-Desmethoxystreptonigrin is an antibiotic originally isolated from Streptomyces and a derivative of the antibiotic streptonigrin. It is active against a variety of bacteria, including S. aureus, S. faecalis, E. coli, K. pneumoniae, and P. vulgaris (MICs = 0.4, 1.6, 3.1, 3.1 and 0.4 μg/ml, respectively). 10'-Desmethoxystreptonigrin is cytotoxic to HCT116 colon and A2780 ovarian cancer cells (IC50s = 0.004 and 0.001 μg/ml, respectively), as well as HCT116 cells resistant to etoposide and teniposide and cisplatin-resistant A2780 cells (IC50s = 0.003, 0.001, and 0.01 μg/ml, respectively). 10'-Desmethoxystreptonigrin is also an inhibitor of p21ras farnesylation (IC50 = 21 nM).

Alamethicin F50 is a peptaibol isolated from Trichoderma. It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids. Alamethicin F50 is a mixture of 13 different peptides, with the most abundant designated as alamethicin F50/5. Alamethicin F50 forms voltage-dependent ion channels in lipid membranes and acts as a lytic agent. It induces lysis of leukocytes (IC50 = 54 and 80 μM for rat mast cells and mouse spleen lymphocytes, respectively) and exhibits antibacterial activity against a panel of 8 mollicutes (MICs = 1.56-12.5 μM).

Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) increases survival in a mouse model of lethal S. pyogenes infection in a dose-dependent manner. Dietary administration of phenelfamycin E increases body weight in chickens.

Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.

Primidolol is a beta adrenergic receptor antagonist and antihypertensive agent.

Nikkomycin N is a bioactive chemical.

PD 116152 is a highly substituted phenazine with antitumor activity isolated from the culture broth of a Streptomyces sp. The antitumor activity versus murine P388 leukemia is T/C 149. PD 116152 is selectively active versus the bacterium Streptococcus pne