Antifungal

Dictyopanine A 显示出较窄的抗菌谱，主要对某些丝状真菌和革兰氏阳性菌具有中等水平的抗菌活性。

Phellinsin 以选择性抑制几丁质合成酶 I 和 II 的活性而著称，其IC50(μg/mL)值分别为76和28。它对炭疽菌、稻瘟病菌、烟曲霉及须癣毛癣菌等病原菌表现出抑菌作用，MIC在12.5-50 μg/mL之间。

Mathemycin A 对病原真菌有抑制作用，在体外对疫霉菌 JO8 的最低抑菌浓度 (MIC) 为 7.8 μg/mL，在温室实验中，其对 JO8 的半数致死剂量 (LD50) 为 42 X 10^-6，致死浓度90% (LC90) 为 500 X 10^-6。

Polyoxin G 是一种核苷类抗真菌抗生素，[对水稻纹枯病有显著效果]。

Fulvoferruginin 是一种具细胞毒性并对真菌，特别是拟青霉，有抑制作用的化合物。

N-563 promotes resistance to Candida albicans infection in mice

Benzohydroxamic acid (BHA) 是一种针对几丁质脱乙酰酶 (CDA) 的抑制剂，展现出显著的抗真菌活性。在对Verticillium dahliae和Puccinia striiformisf. sp. tritici的CDA作用上，其Ki值分别为8.31 μM和9.83 μM。Benzohydroxamic acid 能恢复受感染植物的防御反应，提升防御相关基因的表达，抑制真菌在植物中的生长和繁殖。这种化合物可应用于抗农业真菌病害的研究，如棉花枯萎病和小麦条锈病等由大丽轮枝菌和条锈菌引发的植物病害。

6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties.1 It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (15 and 30 μg/disc in the paper disc assay), and also drug-resistant P. falciparum strain K1 (IC50 = 21 μg/ml).2 |1. Sasaki, T., Igarashi, Y., Ogawa, M., et al. Identification of 6-prenylindole as an antifungal metabolite of Streptomyces sp. TP-A0595 and synthesis and bioactivity of 6-substituted indoles. J. Antibiot. (Tokyo) 55(11), 1009-1012 (2002).|2. Nkunya, M.H., Makangara, J.J., and Jonker, S.A. Prenylindoles from Tanzanian Monodora and Isolona species. Nat. Prod. Res. 18(3), 253-258 (2004).

Vibunazole is an antifungal agent.

Avenaciolide is a water-insoluble fungal metabolite originally isolated from A. avenaceus. It inhibits glutamate transport in isolated rat liver mitochondria (Ki = 8 μM).

1-Undecanoyl-rac-glycerol is a monoacylglycerol that contains undecanoic acid at the sn-1 position. It completely inhibits the growth of the bacteria B. cereus, B. subtilis, M. luteus, E. faecalis, and S. aureus when used at concentrations ranging from 250 to 1,500 mg/L.1 1-Undecanoyl-rac-glycerol (0.1 and 0.3 mg/ml) also has antifungal activity against K. marxianus, S. cerevisiae, and C. maltosa.2

Nikkomycin pseudo-J is a nikkomycin isolated from Streptomyces tendae.

(+)-Xylariamide A is a probe used for mycobacterial and fungal carbonic anhydrase.

Fenpicoxamid is a biochemcial.

Janthitrem f, as a 10-0-acetyljanthitrem e or janthitrem e monoacetate, is a type ofnaphthopyran. Janthitrem F is prepared by Penicillium janthinellum. Tremorgenic mycotoxi.

Pterophyllin 2 is an agent of natural antifungal. It also against postharvest fruit pathogenic fungi.

Julifloricine is an alkaloid isolated from Prosopis juliflora that has antimicrobial activity.

Kinamycin B is an antibacterial agent with anticancer activity.

Lienomycin is a pentaene macrolide antitumor antibiotic generated by Actinomyces vendargensis Struyk et Stheeman. It has inonphore-like action.

Lepiochlorin is an antibiotic metabolite from fungus (species of Lepiota) cultivated by gardening ants.

Rhizocticin A is a potential inhibitor of threonine synthase.

Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.

SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.

Sch 31828 is an antibiotic from Microbispora.

16,17-Dihydroheronamide C 是一种用做 heronamide C 作用模式分析的探针，具有抗真菌作用。

Neoenactin B2 展示出强大的抗酵母和丝状真菌的效果。

Crotocin 具有对新型隐球菌、白色念珠菌和啤酒酵母木霉的杀菌活性，但会被血液灭活。

Enactin Ia 存在于玫瑰绿链霉菌 (Streptomyces roseoviridis) 中，其抑菌活性相对较弱。

Phoslactomycin B 对真菌具有较强作用，但对革兰氏阳性菌的作用较弱。

Fusacandin B 抑制 (1,3)-β-葡聚糖合成酶，展现抗真菌特性。

Cladosporide B 拥有抗烟曲霉活性。

Neoenactin A 对酵母和丝状真菌表现出强大的抗真菌活性。

Fusacandin A 具有抑制 (1,3)-β-葡聚糖合成酶的能力并展现抗真菌特性。

EnactinVa由玫瑰绿链霉菌 (Streptomyces roseoviridis) 生成，其抗真菌作用相对较弱。

Shizukanolide F是一种天然产物，属于金粟兰科金粟兰属，其产品编号为 TN5008，CAS号为 120061-96-3。Shizukanolide F可用作对照参考。

Solaso​​dine hydrochloride（90 μM；2 天）处理后，P19 细胞明显增生。此化合物强烈诱导多种神经元特异性标志物的表达，包括 βIII-微管蛋白、突触素、MAP2、ChAT 及神经母细胞标志物双皮质素。主要通过推动 P19 细胞向神经通路的分化，Solaso​​dine hydrochloride 显示其在神经生物学研究中的潜在应用价值。