Others

CHAPSO 是非变性的两性离子型去垢剂，是一种表面离子活性剂，可用于增溶膜蛋白和裂解蛋白-蛋白之间的相互作用。

Cemdisiran（终端糖基修饰）是一种靶向C5 mRNA的siRNA，通过N-乙酰半乳糖胺缀合增强RNAi活性，能够抑制肝脏中补体成分C5的生成。

Fluproquazone is a quinazolinone derivative with potent antipyretic, analgesic, and anti-inflammatory effects. However, it was withdrawn during development due to liver toxicity.

Sorbitan monolaurate (Arlacel 20) 是一种脱水山梨醇酯表面活性剂，常用于护肤品行业。

TH5427 hydrochloride is a potent and selective inhibitor of NUDT5 with an IC50 of 29 nM. It demonstrates a remarkable 690-fold selectivity towards NUDT5 compared to MTH1. Moreover, TH5427 hydrochloride effectively inhibits progestin-dependent, PAR-derived nuclear ATP synthesis in breast cancer cells, thereby impeding chromatin remodeling, gene regulation, and ultimately suppressing proliferation.

Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells.

(4S)-N-(tert-butyldimethylsilyl)azetidin-2-one-4-carboxylic Acid是一种手性氮杂环丁烷衍生物，主要用作药物合成中间体。

Diazepinomicin is a secondary metabolite produced by Micromonospora sp. It inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. Diazepinomicin also is an anti-tumor agent for K-Ras mutant models.

Rac)-Tanomastat ((Rac)-BAY 12-9566) 是 Tanomastat 的外消旋体。其中 Tanomastat (BAY 12-9566) 是一种口服具有活力的、含锌羧基的非肽联苯基质金属蛋白酶(MMPs)抑制剂，能够抑制 MMP-2 (Ki: 11 nM)、MMP-3 (Ki: 143 nM)、MMP-9 (Ki: 301 nM)、MMP-13 (Ki: 1470 nM)。在几种实验性肿瘤模型中，Tanomastat 表现出抗侵袭和抗转移作用。

MK-2206 是一种具有口服具有活力的、高效选择性的变构 Akt 抑制剂，能够作用于 Akt1 (IC50: 8 nM)、Akt2 (IC50: 12 nM) 和 Akt3 (IC50: 65 nM)。许多乳腺癌细胞系、PIK3CA 突变体和 PTEN 丢失细胞系对 MK-2206 敏感。MK-2206 具有抗癌作用。

MAO-B-IN-5 是一种有效的、选择性和具有口服活性的MAO-B 抑制剂，IC50值为 0.204 μM。MAO-B-IN-5 在帕金森病 (PD) 中具有研究潜力。

4,4-Dimethyl-2-cyclopenten-1-one为Apocyniveneti Folium的源植物衍生的天然产物，展示了对多种肿瘤细胞的高选择性毒性。

Anti-Trypanosoma cruzi agent-4是克氏锥虫抑制剂。Anti-Trypanosoma cruzi agent-4 可用于感染的研究。

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside utilized in the synthetic process of deoxyribonucleic acid (DNA) or nucleic acid.

Org 43553 是口服具有活力的低分子量 (LMW) 促黄体生成素受体(LH-R)激动剂，能够激动人 LH (EC50: 3.7 nM)和 FSH 受体(EC50: 110 nM) 。Org 43553 能够用于研究内分泌。

Tezacitabine 是一种抑制细胞生长和细胞毒性的抗代谢物。 Tezacitabine 是一种核苷类似物，具有双重作用机制。 Tezacitabine 不可逆地抑制核糖核苷酸还原酶，并可在复制或修复过程中掺入 DNA，导致 DNA 链终止。 Tezacitabine 在细胞周期的 G1 期和 S 期阻断肿瘤细胞并诱导凋亡细胞死亡。 Tezacitabine 具有治疗白血病和实体瘤的潜力[1][2]。

m-PEG21-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-propargyl-PEG13 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

mTOR/HDAC-IN-1 (Compound 50) 是一个具有选择性的mTOR 和HDAC 双重抑制剂，对mTOR 和HDAC1的IC50分别为0.49和0.91 nM。 mTOR/HDAC-IN-1 可作为抗癌活性分子 （anti-cancer） 进行研究。该化合物的粉末形式不稳定，建议选择其他盐形式产品。

S22153 is an antagonist of melatonin receptor.

group I/group II metabotropic glutamate receptor antagonist

Propanil is a widely used contact herbicide. It is mainly used in rice production.

Chitin synthase inhibitor 13 (compound 12g) 为非竞争性几丁质合酶抑制剂，其IC50为106.7 μM，展现出广谱抗真菌活性。

XA-E是一种从A. keiskei中提取并通过甲醇-乙酸乙酯纯化得到的化合物。该化合物展现出对ZIKV（Zika病毒）的抗活性，其半抑制浓度（IC50）为22.0 µM。

L-α-Aminoadipic Acid对Metabotropic glutamate receptor具有生物活性，可用于生化实验和药物合成。

L659989 is an antagonist of PAF receptor.

CCG-273220 是 G 蛋白偶联受体 (GPCR) 激酶 5 (GRK5) 共价抑制剂 (IC50: 220 nM)。CCG-273220 可以共价结合GRK5亚家族特异性残基 Cys474 ，而对GRK5的选择性比 GRK2 高。

2'-O,4'-C-Methylenecytidine is a Nucleoside Derivative - LNA-related nucleoside.

(Rac)-Lanicemine ((Rac)-AZD6765) 是 Lanicemine 的外消旋体。Lanicemine (AZD6765) 是一种低捕获的NMDA 受体拮抗剂，Ki 为 0.56-2.1 μM；在CHO 和非洲爪蟾卵母细胞中，IC50分别为 4-7 μM 和 6.4 μM。Lanicemine 具有抗抑郁作用。

Lofepramine is a serotonin and norepinephrine reuptake inhibitor. Lofepramine is also a psychotropic IMIPRAMINE derivative.

m-PEG3-Aminooxy is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

5-HT2 receptors agonist

Calcium Stearate is a potent Alternative to Poly(vinyl alcohol) in Poly-Lactic-co-Glycolic Acid Nanoparticles Synthesis.

Desfluoro-atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active inhibitor of HMG-CoA reductase. It has the ability to effectively decrease blood lipids.

Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.

OATD-01 是一种壳三糖苷酶及酸性哺乳动物几丁质酶的高活性抑制剂，对CHIT1具有低纳摩尔活性 (hCHIT1,IC50=23 nM)。它在多个物种中显示出良好的药代动力学特征，在体内具有显著的抗纤维化活性，可用于研究肺纤维化。