Others

Alpha-Toxicarol exhibits a marked inhibitory effect on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test.

Rhein 8-Glucoside 是一种蒽醌糖苷，存在于大黄 (rhubarb) 中，显示出泻下活性。

ZY-444具有潜在的抗癌活性，抑制 PCa 细胞的增殖和转移，抑制皮下肿瘤的生长。

3-Ethylbenzoic acid是一种芳香化合物，广泛应用于生物化学实验和药物合成研究。

3-Chloro-5-hydroxybenzoic acid 是一种口服具有活力的乳酸受体GPR81选择性激动剂，对人 GPR81 的EC50为 16 μM。肥胖小鼠模型中，它表现出良好的体内脂肪分解作用。

Lucifer Yellow CH dilithium salt 是一种荧光染料，可常用于选择性染色和研究光动力破坏真核细胞和亚细胞结构。

L-aspartic acid potasium salt（VX-548） 是一种广泛存在于动植物体内的氨基酸。L-aspartic acid potasium salt驱动氮氧化物的产生，从而促进吞噬作用，有助于提高鱼类的成活率。L-aspartic acid potasium salt 可对抗生素产生刺激，刺激作用可能与参与天冬氨酸-4-半醛生物合成的前体有关。

PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis. It is specifically designed for the creation of proteolysis-targeting chimeras (PROTACs)[1].

N-Benzyl-N-bis-PEG2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TG41 is a GABAA receptors positive modulator.

hCAII-IN-2 是胞质型人碳酸酐酶 (hCA) 抑制剂，能够作用于 hCA I (Ki: 261.4 nM)、hCA II (Ki: 3.8 nM)、hCA IX (Ki: 19.6 nM)和 hCA XII (Ki: 45.2 nM)。

1-(Tetrahydrofuran-2-Yl)Ethanone是一种有机化合物。它由一个直接连接乙酰基能团的四氢呋喃（THF）环结构组成，主要用作复杂有机合成中的多功能化学中间体，特别是用于药品和农用化学品的生产。

Gemcadiol is a new antilipemic drug.

K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The compound has the potential to be used in the synthesis of PROTAC K-Ras Degrader-1, a powerful degrader of K-Ras that has been shown to exhibit a degradation efficacy of ≥70% in SW1573 cells[1].

Nicotinamide riboside tartrate (NRT) is an oral NAD+ precursor that raises NAD+ levels, activates SIRT1 and SIRT3, and serves as a vitamin B3 (niacin) source. NRT also improves oxidative metabolism and protects against metabolic abnormalities induced by a high-fat diet. Furthermore, NRT mitigates cognitive decline in a transgenic mouse model of Alzheimer's disease.

ACG548B (compound 24) is a highly effective inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50 values of 1.78 and 0.496 μM, respectively. It exhibits a greater affinity for AChE and demonstrates selectivity over BChE and ChoK (choline kinase).

Lugrandoside 是一种新型的苯丙素苷，它已从洋地黄和 Difitalis Grandiflora Miller 的茎叶中分离得到。

A potent modulator of cell proliferation and differentiation.

Larsucosterol sodium is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.

Mycro1 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max.

PCSK9-IN-20（Compound 3i）作为一种PCSK9抑制剂，具有IC50为 3.96 µM，能有效降低体外PCSK9水平并提升LDLR蛋白表达。

URAT1 inhibitor4 是一种Lesinurad 的衍生物，是口服有效的URAT1抑制剂，IC50为 7.56 μM。URAT1 inhibitor4具有比Lesinurad 更高的体内降尿酸效力。

20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This ω-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing recombinant human CYP4F3B. Like 20-HETE, 20-COOH-AA inhibits ion transport in the kidneys. It also produces vasorelaxation of porcine coronary microvessels constricted with endothelin. 20-COOH-AA binds to isolated ligand binding domains of peroxisome proliferator-activated receptor α (PPARα) (Kd = 0.87 ± 0.12 μM) and PPARγ (Kd = 1.7 ± 0.5 μM), and is a dual activator of PPARα and PPARγ in a transiently transfected COS-7 cell reporter system.

Isavuconazole (Standard) 是一种可用于分析的标准物质，通常用作 Isavuconazole 的研究和分析中参考的标准样品。Isavuconazole (RO-0094815) 是一种三唑类前药，对酵母、霉菌和二型真菌具有抗真菌活性。它抑制麦角固醇生物合成，导致真菌膜结构和功能的破坏。它是 CYP3A4抑制剂。

Cu (II) Protoporphyrin IX functions as a negative control for Zn (II) Protoporphyrin, a heme oxygenase inhibitor. Heme oxygenase is involved in tumor cell resistance to chemotherapy and the regulation of free radical formation, inflammation, and vascular repair.

2-Oxopropyl acetate是一种酯类和酮类化合物，广泛应用于生物化学实验和药物合成研究。

Sodium Thiosulfate Pentahydrate 是一种具有还原性的无机盐，主要用于治疗氰化物中毒、缓解化疗副作用与中和氯气。

1-(1-Hydroxynaphthalen-2-yl)ethan-1-one是一种芳香类化合物，广泛应用于生物化学实验和药物合成研究。

Azido-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bestatin trifluoroacetate (Ubenimex trifluoroacetate) 是一种 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂，经常用于研究癌症。

Showdomycin is an antibiotic with antineoplastic activity.

Glycosmisic acid is a natural product from Nauclea officinalis.

Rifamycin, a natural antibiotic, inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, leading to the block of RNA-polymerase transcription initiation.

Kuguacin N 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126345。

Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.