Others

A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication.

AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.

ABT-299 is a prodrug of A-85783.

A-80b is a synthesized pyridazino[4,5-b]indole derivate with potent and long-lasting antihypertensive activity. The decrease in diastolic pressure was greater than the decrease in systolic pressure and cardiac frequency was not modified significantly. A-8

Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.

Avorelin, a luteinizing hormone releasing hormone (LH-RH) agonist, is used potentially for the treatment of prostate.

ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.

BDF 9148, a Na(+)-channel modulator, increases the contractile force of guinea-pig atria and papillary muscles.

Sphingomyelin (d18:1/12:0)为一种具调节细胞信号传导功能的极性脂质，它在细胞膜中扮演着至关重要的角色，不仅影响膜的流动性和稳定性，还参与脂质代谢并促进神经细胞生长。此外，Sphingomyelin (d18:1/12:0)在神经系统的功能发育中也具有不可或缺的作用。

Diethylumbelliferyl phosphate (DEUP) 作为一种选择性的强效胆固醇酯酶抑制剂，能防止胆固醇被运输到类固醇生成细胞的线粒体，从而有效抑制类固醇的生成。在体外环境中，DEUP不会对蛋白激酶活性A造成抑制。此外，其IC50值为 11.6 μM，表明该化合物能够在一定程度上阻止膳食胆固醇的吸收。

06:0 PE (PE(6:0/6:0)) 是一种具有短酰基链的水溶性磷脂，其特点是具有抗肿瘤活性和能够抑制肿瘤在体内的发展。此外，它还展现出抗增殖和促进细胞凋亡的功能，并可作为磷脂酰胆碱与磷脂酰乙醇胺的前体。

Benanserin HCl is a serotonin antagonist. It causes psychotropic effects in humans.

CP-944629 is a novel, potent, and selective inhibitor of p38alpha.

CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain.

BNC-1 is a modulator of amyloid pathology. BNC-1 significantly decreases amyloid burden and improves markers of synaptic integrity in well-established mouse models of amyloid deposition by promoting phosphorylation and activation of Elk-1.

BRL 55834, a potassium channel activator, has shown to relax airways and vasculature in vivo.

Bromadoline is an opioid analgesic selective for the μ-opioid receptor.

CAY10397, a selective inhibitor of 15-hydroxy PGDH, significantly suppresses endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE.

CGI-17341 is an orally active representative of the 5-nitroimidazole series of antimicrobial agents. CGI 17341 inhibits the drug-susceptible and multi-drug-resistant strains of Mycobacterium tuberculosis at concentrations ranging from 0.1 to 0.3 microgram

CGP-28014 is an inhibitor of catechol-O-methyltransferase. CGP-28014 increases the renal excretion of both dopamine and dihydroxyphenylacetic acid (DOPAC) but does not affect renal sodium handling indicating a different mechanism of action. CGP-28014 sign

CGP 47656 is an agonist of GABAB receptor.

DBPR-110 is a nonstructural protein 5A (NS5A) inhibitor. DBPR-110 reduced the reporter expression of the HCV1b replicon with a EC(50) and a selective index value of 3.9 ± 0.9 pM and >12,800,000, respectively. DBPR-110 reduced HCV2a replicon activity with

NEU-730, a novel inhibitor of TbrPDEB1, shows modest inhibition of T. brucei proliferation.

ICI-56780, a antimalarial agent, displays blood schizonticidal activity against P.berghei.

HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.

JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.

Chlorpropylate is an insecticide.

E55888 is a potent and selective full agonist of the 5HT7 serotonin receptor.

SAR114137是一种具备高效性和强大生物活性的化合物。在晶体活性药物成分的物理处理中，SAR114137展示了其变化的无定形(API)含量。特别是经过各种喷射磨削技术处理后，其无定形API含量将显著减少。此外，SAR114137在药物制剂中还保持了良好的化学稳定性。

FR190997 is an agonist of bradykinin B2 receptor.

MRS2496 is a P2Y(1) receptor antagonist.

Silicon naphthalocyanine dichloride是一种含有抗肿瘤潜力的光敏化合物。在光动力疗法中，此化合物通过吸收特定波长的光能产生氧自由基，进而有效地破坏癌细胞。Silicon naphthalocyanine dichloride的良好生物相容性，使其在医学领域具有广阔的应用前景。

LRAT-IN-1（compound 1）作为视黄醇酰基转移酶（LRAT）的抑制剂，展示出显著的活性（IC50=21.1 μM）。该化合物能够通过阻断视黄醇的酯化过程，从而增加皮肤中视黄醇的可用性，进而提供抗衰老效果。LRAT-IN-1主要用于化妆品中，作为抗衰老成分进行深入研究。

Erizepine，作为一种章鱼胺受体 3 (OAR3) 拮抗剂，其Ki值达到474 nM，主要用于昆虫学研究领域。

Glasmacinal 是一种大环内酯类化合物，具有显著的抗炎活性。

PZ-3022 是一种变构PanK激活剂，具有口服活性，能有效抵消 C3-CoA 的抑制作用。在丙酸血症小鼠模型中，PZ-3022 能够提高肝脏中的 CoASH 和 C2-CoA 水平，同时减少 C3-CoA。此化合物适用于研究丙酸血症中的线粒体功能障碍。