Others

Decyl-β-D-Selenomaltoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0111，CAS号为 1423269-77-5。

Oxanosine is an analog of guanosine that has been found in S. capreolus and has diverse biological activities, including antibacterial, antiviral, and anticancer properties. It is active against a variety of bacteria, including S. flexneri, P. mirabilis, and E. coli (MICs = 6.25, 12.5, 25 µg/ml, respectively, on peptone, but not nutrient, agar). Oxanosine inhibits replication of the HIV-1 strain IIIb in infected CEM and U937, but not H9, cells (EC50s = 7, 27, and >500 µg/ml, respectively). It also inhibits the growth of HeLa human cervical cancer cells (IC50 = 32 µg/ml) and reduces tumor growth in a murine L1210 lymphocytic leukemia model.

TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.

AMD-3329 hydrobromide is a biochemical in the class of potent and selective anti-HIV-1 and HIV-2 agents that inhibit virus replication by binding to the chemokine receptor CXCR4, the co-receptor for entry of X4 viruses.

Salacinol is a naturally occurring alpha-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata.

TAC 363 is a tachykinin NK-2-receptor antagonist.

BW-10 potently inhibits bombesin evoked release of gastrointestinal hormones in vitro and in vivo.

C13-113-tetra-tail 是一种阳离子类脂化合物，可用于配制脂质纳米颗粒。

MLN-0415 is an IKK2 inhibitor which decreases NF-κB activation and down-regulates the expression of a number of inflammatory proteins.

TY 11345 is a proton pump inhibitor.

Modimelanotide is a melanocortinergic peptide drug derived from α-melanocyte-stimulating hormone (α-MSH) which was under development for the treatment of acute kidney injury. It acts as a non-selective melanocortin receptor agonist.

GCC-4401C methanesulfonate is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE).

Mepazine hydrochloride monohydrate is a MALT1 inhibitor.

AM6580 is an irreversible monoacylglycerol lipase (MGL) inhibitor.

AG-12286 is a pan-CDK inhibitor. AG-012986 may be useful in the treatment of tumors by inhibiting p38 MAPK phosphorylation. Note: many vendors confused the structure of AG-12286 (CAT#573461, CAS# 223784-75-6) with AG-012986 (CAT#406184, CAS# is 486414-35-1).

Antitumor agent-46 是一种抗肿瘤剂。Antitumor agent-46 对 MCF-7 细胞具有明显更高的抗增殖活性，IC50值为 2.08 µM。

AL-6556 is a prostaglandin DP receptor agonist.

PrCP-7414, also known as PrCP inhibitor with CAS#1252037-41-4, is a potent PrCP inhibitor. For the convenience of communication, it is named as PrCP-7414. The last four digit of its CAS# was used for name.

ISP-VT is a Novel inhibitor of COX and neutrophil migration.

Febuxostat 67M-4 is a derivative compound of Febuxostat 67M-1 which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and reduces the risk of gout or kidney stone formation.

U 88204 is a non-nucleoside HIV-1 reverse transcriptase inhibitor.

Pyrazinecarboxamide, 3,4-dihydro-4-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-oxo- 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU0422L，CAS号为 356783-01-2。该化合物的粉末形式不稳定，建议选择其他盐形式产品。

RU1968 bis-TFA salt is an inhibitor of the sperm-specific Ca2+ channel CatSper, thereby inhibiting human Slo3 with about 15-fold lower potency than CatSper.

Aspirin calcium is the prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Decyl Glucose Neopentyl Glycol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0079，CAS号为 1423314-52-6。

Nilotinib N-oxide is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.

6-Chloropurine riboside-5'-triphosphate是一种RNA三磷酸酶mRNA-帽化酶β亚单位(Cet1; IC50 = 2 µM，针对S. cerevisiae酶的GTPase活性)的抑制剂，同时也是6-chloropurine riboside的磷酸化形式。此外，它还能激活E. coli天冬氨酸氨甲酰转移酶(EC50 = 0.76 mM)。6-Chloropurine riboside-5'-triphosphate已在合成具有抗癌活性的细胞因子以及一种光点击形式的ATP中得到应用。

AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.

Secoverine is a selective muscarinic receptor antagonist that was studied as a neurotropic spasmolytic agent. It was shown that the drug had no nicotinolytic or antihistaminic activity, a moderate antisterotonic activity, an inhibiting effect on the noradrenaline uptake mechanism of the vas deferens and marked local anesthetic activity.

Saussureamine C is an inhibitor of H274Y and N294S mutants.

Indimitecan HCl is a TOP1 inhibitor chemical scaffold.

Cefonicid monosodium is the salt form of Cefonicid (free base), a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Tozasertib lactate is a potent and selective small-molecule inhibitor of the Aurora kinases which suppresses tumor growth by inducing apoptosis in tumor cells in which Aurora kinases are overexpressed.

Avotaciclib sulfate is a cyclin-dependent kinase inhibitor and antineoplastic.

Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor.

AZD3676 is a novel dual antagonist of serotonin 5-HT1A and 5-HT1B receptor.