RAAS

[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用（如正常动脉的收缩，培养的细胞或病变血管的肥大或增生等）的多肽，。

Benazepril hydrochloride (CGS 14824A HCl) 是一种血管紧张素转化酶（ACE）抑制剂，能够作用于高血压。

CL-329167(compound 12)是一种口服活性和竞争性的血管紧张素II (angiotensin II) 受体拮抗剂 (IC50=6 nM)，可用于研究高血压。

ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).

Olodanrigan sodium （EMA-401 sodium）是一种具有口服活性和选择性的血管紧张素 Ⅱ 类型 2 受体 (AT2R) 拮抗剂，可用于研究神经系统疾病。

AT2R antagonist 1 是一种高度选择性的、有效的 AT2R (血管紧张素 II AT2 受体)配体。AT2R antagonist 1 能够高度亲和 AT2R 亲和力 (Ki: 29 nM)。AT2R antagonist 1 能够抑制常见的药物代谢CYP 酶，在人、大鼠和小鼠肝微粒体中具有较高的稳定性。

TA-606 is an angiotensin type 1 receptor antagonist with antihypertensive activity.

Cgp 44099 is a potent plasma renin inhibitor from all subprimate species.

DuP-532, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension and heart failure.

LY285434 is a suitable angiotensin II receptor antagonist.

A 81282 is a selective antagonist of angiotensin receptors. It has the activity of lowering blood pressure.

LY301875 is an antagonist of nonpeptide angiotensin receptor.

Novokinin TFA is a peptide agonist of the angiotensin AT2 receptor.

Tolmesoxide (RX71107) 是一款具备降血压功能的外周血管扩张剂。它在人体前臂动脉床及手背静脉中展现出直接的血管扩张作用，能够剂量依赖性地提升前臂血流量，并在手背静脉收缩时显示扩张效果。此化合物主要用于高血压与心绞痛的研究。

Cytosporin A 是六氢苯并吡喃衍生物，也是血管紧张素 II 受体拮抗剂。针对AT1受体的IC50为25-30 μM，针对AT2受体的IC50为1.5-3 μM。

AZ11657312 is a P2X7 receptor antagonist.

SR 42128 is arginine salt.

5-methyl-2-HOBA is an isoketal scavenger. It reduces angiotensin II-induced increases in systolic blood pressure in mice.

SR 43845 is an inhibitor of renin.

Fonsartan is an angiotensin receptor antagonist. Fonsartan inhibits the angiotensin II-induced trophic effects, fibronectin release and fibronectin-EIIIA+ expression in rat aortic vascular smooth muscle cells in vitro.

A81988 is an antagonist of angiotensin AT1 receptors.

Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.

L 363564 is a kidney renin inhibitor.

ES 8891 is an inhibitor of renin.

LY303336 is an antagonist of AT1 receptor.

Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic.

Ciprokiren is a renin inhibitor discovered by Roche. Ciprokinen inhibited human renin in a buffer and human plasma with an IC50 of 0.07 and 0.65 nmol/L, respectively. In animal models, acute and chronic administration of ciprokinen lead to a reduction in arterial blood pressure. Development of ciprokinen was discontinued at a preclinical stage.

PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.

EMD-66684 is a non-peptide angiotensin II receptor antagonist.

RG 13647 is an agonist of angiotensin II peptide.

Mca-YVADAP-Lys(Dnp)-OH是caspase-1和ACE2(血管紧张素转换酶 2) 的荧光底物，用于检测酶活，被切割后Mca基团释放荧光信号，激发/发射波长约为365/440nm。

SQ 32970 is a potent Endothia aspartic proteinase inhibitor.