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蒽酮类
TargetMol可提供1.9万种天然产物,包括蒽酮类(Xanthones)相关产品,来源清晰,结构多样,可提供拉丁学名。
HIT213885771
Kielcorin
TN4388
64280-48-4
Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils (IC (50) = 965.21 ± 65.80 uM). trans-Kielcorin has hepatoprotective activity, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes.
Antifection
HIT213885770
3,4-Dihydroxy-2-methoxyxanthone
TN2876
6702-55-2
3,4-Dihydroxy-2-methoxyxanthone 显示出抗菌和保肝活性,它能防止叔丁基过氧化氢诱导的新鲜离体大鼠肝细胞的脂质过氧化和细胞死亡,并在一定程度上有效防止细胞谷胱甘肽平衡的扰乱。
Antibacterial
HIT213885000
Formoxanthone A
TN4071
869880-32-0
Formoxanthone A 可能具有抗菌和细胞毒性活性。
Antifection
Apoptosis
HIT213885484
1,3,7-Trihydroxy-2-prenylxanthone
TN2489
20245-39-0
1,3,7-Trihydroxy-2-prenylxanthone (Isombarraxanthone) 显示出较弱的抗菌活性。
Antibacterial
Antifection
HIT213886678
Drimiopsin D
TN3898
773850-91-2
Drimiopsin D (1) is a natural product extracted from Scilla scilloides. It has a molecular formula of C24H28O5 and a molecular weight of 396.47. This compound possesses potential medicinal properties, particularly in pharmacological and biochemical research.
Others
HIT213885486
Garcinone E
TN4113
112649-21-5
Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.
Antifection
Apoptosis
HIT213885089
3,8-Dihydroxy-2,4,6-trimethoxyxanthone
T4617
65008-17-5
3,8-Dihydroxy-2,4,6-trimethoxyxanthone是一种天然产物,属于蹄盖蕨科冷蕨属,其产品编号为 T4617,CAS号为 65008-17-5。3,8-Dihydroxy-2,4,6-trimethoxyxanthone可用作对照参考。
Others
HIT213840731
3-Isomangostin
T2S1635
19275-46-8
3-Isomangostin 可从莽吉柿壳中提取的一种天然产物,是一种乙酰胆碱酯酶选择性抑制剂,也是一种有效的人醛糖还原酶抑制剂,IC50 为 3.48 uM。它抑制 MutT 同源物 1 (MTH1),IC50 为 52 nM。它具有清除自由基、抗疟原虫和抗癌的活性。
DNA/RNA Synthesis
MTH1
HIT213885472
3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone
TN2862
1432062-53-7
3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2862,CAS号为 1432062-53-7。
Others
HIT213885487
1-Isomangostin
TN2546
19275-44-6
1-Isomangostin 具有细胞毒性和抗补体活性。
Lipase
NF-κB
HIT213885906
Isocudraniaxanthone B
TN4276
199851-52-0
Isocudraniaxanthone B may have antimalarial activity.
Antifection
Sodium Channel
HIT213885485
Mangostanol
TN4492
184587-72-2
Mangostanol is an acetylcholinesterase (AChE) selective inhibitor.Mangostanol has anti-cancer activity, it shows significant activities against the CEM-SS cell line, with IC50 values of 9.6 microg/ml.
AChR
PDE
HIT214317078
1,5,6-Trihydroxy-3,7-dimethoxyxanthone
TN5902
65008-02-8
1,5,6-Trihydroxy-3,7-dimethoxyxanthone shows cytotoxic activity against the KB cell line.
HIT214309871
2,3',4,6-Tetrahydroxybenzophenone
TN2687
26271-33-0
2,3',4,6-Tetrahydroxybenzophenone possesses significant antioxidant activity.
Cytochromes P450
HIT213885593
1-Hydroxy-2,3,5-trimethoxyxanthone
TN2534
22804-49-5
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type voltage-operated Ca(2+) channels; a minor contribution to the effects of HM-1 may be related to inhibition of the protein kinase C-mediated release of intracellular Ca(2+) stores. HM-1,at the concentration of 1 ug/mL, can effectively inhibit the osteoclast differentiation in a co-culture system with mouse osteoblastic calvarial cells and bone marrow cells; it also can protect mice from the acute lung injury induced by ipopolysaccharide (LPS), which is relative to the increasing of IκB-α protein expression and the suppressing of inducible nitric oxide synthase and cyclooxygenase-Ⅱ protein expression.
5-HT Receptor
Calcium Channel
COX
IκB/IKK
NOS
HIT213885326
Subelliptenone G
TN5075
162473-22-5
Subelliptenone G is a natural product from Garcinia hanburyi Hook.f.
Others
HIT213886352
1,7-Dihydroxy-2,3-methylenedioxyxanthone
T4484
183210-63-1
1,7-Dihydroxy-2,3-methylenedioxyxanthone exhibits antiulcerogenic, anti-oxidation, and antihyperalgesic activities and can inhibit carrageenan-induced hyperalgesia.
Antifection
Prostaglandin Receptor
HIT213886868
Ugaxanthone
TN5197
13179-11-8
Ugaxanthone is a natural product from Symphonia globulifera L.
Others
HIT213885471
8-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane
TN3272
63565-07-1
8-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3272,CAS号为 63565-07-1。
Others
HIT103583084
4-Hydroxyvertixanthone
TN4522
85003-85-6
4-Hydroxyvertixanthone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4522,CAS号为 85003-85-6。
Others
HIT213885424
1-Hydroxy-2,3,4,7-tetramethoxyxanthone
TN2533
14103-09-4
1-Hydroxy-2,3,4,7-tetramethoxy-xanthone has vasodilatory action, causing vasodilation in the coronary artery pre-contracted with 1 μM 5-hydroxytryptamine (5-HT), with an EC 50 value of 6.6±1.4 μM.
5-HT Receptor
Endogenous Metabolite
HIT213885036
Cudraxanthone D
TN3727
96552-41-9
Cudraxanthone D是一种天然产物,属于桑科柘属,其产品编号为 TN3727,CAS号为 96552-41-9。Cudraxanthone D可用作对照参考。
Others
HIT211999350
Mangiferin
T3012
4773-96-0
Mangiferin (Hedysarid) 是一种Nrf2激活剂。它抑制NF-κB 亚基p65和p50的核移位,具有抗氧化、抗糖尿病、抗高尿酸血症、抗病毒、抗癌和抗炎活性。
Apoptosis
NF-κB
Nrf2
HIT212665568
Iriflophenone
TN1768
52591-10-3
Iriflophenone 是从 Aquilaria sinensis 中分离得到,能诱导 MCF-7 和 T-47D 人乳腺癌细胞增殖。
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
HIT213884762
Pyranojacareubin
TN4867
78343-62-1
Pyranojacareubin is a natural product from Calophyllum inophyllum.
Others
HIT213885661
6-Deoxyjacareubin
TN3161
16265-56-8
6-Deoxyjacareubin 具有有效的抗氧化和抗真菌活性。 6-Deoxyjacareubin 抑制血小板活化因子 (PAF) 受体,IC50 为 29.0 microM,可用于天然 PAF 受体拮抗剂的研究。
Antifection
Antioxidant
PAFR
Platelet aggregation
Reactive Oxygen Species
HIT213886682
Drimiopsin C
TN3897
773850-90-1
Drimiopsin C is a natural product from Scilla scilloides.
Others
HIT212687446
Sibiricaxanthone A
TMA1948
241125-76-8
Sibiricaxanthone A (Sibiricaxanthone A) 是一种分离自 Polygala sibirica 根茎中的黄原酮 C-糖苷。
Others
HIT213885469
O-Demethylforbexanthone
TN4686
92609-77-3
O-Demethylforbexanthone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4686,CAS号为 92609-77-3。
Others
HIT213885662
5-Hydroxy-1-methoxyxanthone
TN3116
27770-13-4
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B.
Antifection
MAO
HIT213885452
1,6,7-Trihydroxyxanthone
TN2507
25577-04-2
1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.
Apoptosis
BMI-1
DNA/RNA Synthesis
HIT212661632
Norathyriol
TN1990
3542-72-1
Norathyriol 是来自芒果的芒果苷代谢物,具有抗氧化、抗癌、抗菌和抗炎活性。它以非竞争性方式抑制 α-葡萄糖苷酶,IC50为 3.12 μM。它还抑制PPARα、PPARβ和PPARγ,IC50分别为 92.8、102.4 和 153.5 µM。
Akt
AMPK
DNA/RNA Synthesis
Glucosidase
glycosidase
PPAR
HIT213885488
Nigrolineaxanthone V
TN4657
864516-31-4
Nigrolineaxanthone V是一种天然产物,属于藤黄科藤黄属,其产品编号为 TN4657,CAS号为 864516-31-4。Nigrolineaxanthone V可用作对照参考。
Others
HIT213884759
Mesuaxanthone A
TN4519
3561-81-7
Mesuaxanthone A and mesuaxanthone B are two yellow pigments.They produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of pentobarbitone sleeping time and et
Others
HIT213885497
7-Prenyljacareubin
TN3250
94513-60-7
7-Prenyljacareubin shows moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.
Others
HIT213885470
6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane
TN3154
86606-14-6
6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3154,CAS号为 86606-14-6。
Others
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