Antifection

EBNA1-IN-SC7 (compound SC7) 是一种 Epstein-Barr nuclear antigen 1 (EBNA1) 的选择性抑制剂，能够干扰 EBNA1-DNA 结合活性 (IC50: 23 μM)。EBNA1-IN-SC7 能够用于研究 EBV (Epstein-Barr virus) 相关癌症。

Econazole nitrate (NSC-243115) 是一种有抗菌活性的咪唑类抗真菌药物。

Chlorhexidine (Rotersept) 是一种抗菌剂和防腐剂。它可用于注射前、手术前或外伤后清洁皮肤。

Oxiconazole nitrate (Ro 13-8996) 是广谱抗真菌药物，抑制T. tonsurans 和T.rubrum 的生长，MIC90值分别为 0.25 和 0.5 μg/mL。

Arjungenin，来源于Terminalia arjuna的一种三萜类化合物，展现出驱虫和生长抑制的特性。

Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it has cardiovascular effects. Beta-Yohimbine has anti-plasmodial and anti-mal

GSK983, a potent broad-spectrum antiviral, blocks cell proliferation and dengue virus replication by inhibiting the pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase (DHODH).

14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs of 3.74, 14.97, and 7.49 microM , r

Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils (IC (50) = 965.21 ± 65.80 uM). trans-Kielcorin has hepatoprotective activity, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes.

CEF19, Epstein-Barr Virus latent NA-3A (458-466), is a peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain).

Lactoferrin (17-41) (Standard)是一种可用于分析的标准物质，通常用作Lactoferrin (17-41)的研究和分析中参考的标准样品。Lactoferrin (17-41)对革兰氏阳性和革兰氏阴性细菌、病毒、和真菌等微生物具有广谱的抗菌活性。

3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3beta-O-cis-p-Coumaroyltormentic acid, and 3beta-O-trans-p-coumaroyltormentic acid are weakly selective for vancomycin-resistant Enterococcus (VRE) compared with eukaryotic cells, with an MIC of 59.4microg/mL and a 50% inhibitory concentration (IC50) of 72.0microg/mL for monkey kidney epithelial (MA104) cells. A mixture of 3-O-cis-p-coumaroyltormentic acid and 3-O-trans-p-coumaroyltormentic acid shows an inhibitory effect comparable to (-)-epigallocatechin gallate (EGCG) of green tea on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradeca--noylphorbol-13-acetate (TPA).

Coronarin E exhibits weak antimicrobial activity.

14-Deoxy-17-hydroxyandrographolide是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN2623，CAS号为 869384-82-7。14-Deoxy-17-hydroxyandrographolide可用作对照参考。

Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.

1,2,3,4-Tetrahydronorharman-1-one (L-Oxonoreleagnine) 是从印度尼西亚海海绵 Acanthostrongylophora ingens 中分离得到的。

Torachrysone-8-O-b-D-glucoside 可从 Polygonum multiflorum 分离得到。它对 DPCs(真皮乳头细胞)的增殖具有促进作用。

Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.

Isocostic acid may have antibacterial activity.

5-Heneicosylresorcinol 对 RBL-2H3 细胞中 β-己糖胺酶的释放具有抑制作用，它还可以防止 3T3-L1 细胞中甘油三酯的积累。它对红线虫、秀丽隐杆线虫和松材线虫具有杀线虫活性，ED50 值分别为 80、30 和 180 ug/mL。

Globulol shows antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 microg/ mLand 737.2 microg/ mL, respectively.

Rengynic acid has potent antiviral effect on RSV for the first time in vitro.

Bonducellpin D may show inhibitory activities on the Para3 virus. It also exhibits moderate activity against four tested human cancer cell lines, HepG-2, K562, HeLa, and Du145.

7',8'-Dihydroobolactone can inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM.

Rupesin E shows significant antibacterial activities against Escherichia coli.

4-Epialyxialactone exhibits significant antitumor and antibacterial activity.

2α,3α,24-Trihydroxyurs-12-en-28-oic acid, a triterpenoid phytoalexin, shows antifungal activity against the fungus mentioned. It also shows in vitro cytotoxic activity against tumor cell lines including PLC,Hep3B,HepG2,HeLa,SW480,MCF-7 and Bel7402.

Isocudraniaxanthone B may have antimalarial activity.

Pterodontic acid and pterodondiol showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis.

24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli.

Cycloart-23-ene-3,25-diol has anti-inflammatory activity, it has protective activity against streptozotocin induced toxicity. Cycloart-23-ene-3,25-diol treatment can decrease liver malondialdehyde but increase superoxidase dismutase and reduced glutathion

Methylenetanshinquinone shows antiplasmodial and antitrypanosomal activity, it is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.

Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Penduletin has strong activity in vitro against EV71 with low cytotoxicity.

Evofolin C and its acetate show strong antifungal and antibacterial activity. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM.

Methyllinderone is a human chymase inhibitor, it has antioxidant property, it also shows moderate to weak antifungal activities against various pathogenic fungi.

Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal activity against L4 stage larvae.