Others

Scabertopin 是一种从地胆草中分离得到倍半萜内酯，具有抗癌和抑菌活性。

Azido-PEG9-S-methyl ethanethioate is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs).

X-GalNAc是用作检测琼脂板上生长的细菌中克隆DNA插入片段的N-乙酰-β-半乳糖苷酶的显色底物。

UC-1V150 is a distinct TLR7 agonist, which activates cellular immune responses and exhibits anti-tumor effects. It also serves as a precursor for the synthesis of ISAC molecules, known as immune-stimulating antibody conjugates [1] [2].

Pentaethylene glycol monomethyl ether (PEG-MME) is a PEG-based PROTAC linker, which is employed for the synthesis of PROTACs[1].

Acid-PEG4-S-S-PEG4-acid is a polyethylene glycol (PEG)-based PROTAC linker, which serves as a key component in the synthesis of PROTACs.

CLK8 是一种具有选择性的 CLOCK 抑制剂，可结合并干扰 CLOCK 活性，破坏 CLOCK 和 BMAL1 之间的相互作用，可调节昼夜节律振幅。CLK8 可用于研究与昼夜节律相关的疾病。

Admire 是在农业中研究农药的重要化合物。

Tuberculosis inhibitor 8 (compound 3b) 是 3-甲氧基-2-苯基咪唑并[1,2-b]哒嗪衍生物，具有针对结核分枝杆菌 (MIC90为 0.69 μM) 和海洋分枝杆菌 (MIC90为 0.69 μM) 的高抗菌活性。

Ropitoin is a novel drug of antiarrhythmics.

Azido-PEG6-C1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

ATX inhibitor 19 是 ATX 的有效抑制剂 (IC50: 156 nM)。

DBCO-PEG6-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Benzyl-PEG4-MS 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67180，CAS号为 477781-69-4。

Bendazac (Bendazolic acid) 是一种氧乙酸，具有抗过敏、抗炎、利胆和抗血脂作用。它能够阻断蛋白质变性，延缓白内障的发生过程。

SCH 51344 抑制Ras 诱导的恶性转化。SCH 51344可防止癌基因转化的成纤维细胞的非锚定生长。

Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.

ACT-209905 is an agonist of S1P1 receptor.

AR-A 2 is a selective 5-HT1B receptor antagonist, with a high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM) and with 10-fold lower affinity to guinea pig 5-HT1D receptor (Ki: 5 nM).

1,16-Hexadecanediol 毒性较低，可用于制作树脂和纳米材料。

AZ8838 是一种有效的、竞争性的、变构的、口服活性的 PAR2非肽小分子拮抗剂，其对 hPAR2 的 pKi 值为 6.4。

Iloperidone hydrochloride is a D(2)/5-HT(2) receptor antagonist. It is also an atypical antipsychotic for the treatment of schizophrenia symptoms.

MrgprX2 antagonist-4 and compound B-51 E117, is a potent MrgprX2 antagonist. It specifically targets and inhibits the MrgprX2 receptor, making it suitable for investigating various inflammatory skin disorders.

Clofibrin is a kind of hypolipidemic drug, which can reduce Hypertriglyceride and hypercholesterolemia.

FR 901465 is a biochemical.

BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).

Axl-IN-9 是一种 AXL 的有效抑制剂 (IC50: 26 nM)，具有优良的跨膜性。Axl-IN-9 在动物体内表现出良好的药代动力学特性。Axl-IN-9 能够用于研究增生性疾病、自身免疫性疾病、过敏性疾病、移植排斥、炎症性疾病、癌症或其他哺乳动物疾病。

(R)-Necrocide 1（化合物(R)-38）是一种具有抗增殖活性的有效抗癌剂。

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone是一种天然的苯乙酮衍生物，可用于生物化学实验和药物合成研究。

Pseudoneolinderane是一种发现于Neolitsea aciculata Koidz的倍半萜烯，可用于生物化学实验和药物合成研究。

Orexin 2 Receptor Agonist 2 (ORA-2) is a specific agonist for the orexin 2 receptor.

S-acetyl-PEG4-NHBoc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

HDAC-IN-31 是一种选择性的、有效的、口服具有活力的 HDAC 抑制剂，能够作用于 HDAC1 (IC50: 84.90 nM)、HDAC2 (IC50: 168.0 nM)、HDAC3 (IC50: 442.7 nM)、HDAC8 (IC50>10000 nM)。 HDAC-IN-31 能够将细胞周期阻滞在 G2/M 期，并诱导细胞凋亡 (apoptosis)。HDAC-IN-31 具有良好的抗肿瘤效果。HDAC-IN-31 对弥漫性大 B 细胞淋巴瘤表现出潜在的研究价值。

TP-050 是一种口服有效的选择性 NMDAR 激动剂，抑制 GluN2A 和 GluN2D 的 EC50值分别为 0.51 μM 和 9.6 µM。TP-050 可穿过血脑屏障 (BBB)。TP-050 诱导海马区的长期增益效应 (LTP)，增强神经元信号传输。

AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively).