Others

5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modification effects.

Triton X-45, a nonionic surfactant with a low Hydrophile-Lypophile Balance (HLB) value, is a dispersible compound in the aqueous solution at room temperature. With a Krafft point above room temperature, Triton X-45 shows promise for research on the Hepatitis C Virus (HCV).

MY33-3 is a powerful and specific inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, demonstrating an IC50 value of approximately 0.1 μM. Moreover, MY33-3 exhibits inhibitory activity against PTP-1B with an IC50 value of about 0.7 μM. Additionally, MY33-3 has been shown to effectively decrease ethanol consumption and alleviate neuroinflammation and cognitive dysfunction induced by Sevoflurane.

Antileishmanial agent-1 demonstrates activity against both L. amazonensis promastigotes (IC 50 = 15.52 μM) and intracellular amastigotes (IC 50 = 4.10 μM).

FP-biotin is a potent organophosphorus toxicant, ideal for identifying novel biomarkers of organophosphorus toxicant exposure. It measures FAAH, ABHD6, and MAG-lipase activity, specifically in plasma studies, due to the efficient purification of biotinylated peptides through binding to immobilized avidin beads.

Phallacidin, a phallotoxin family member, targets and binds to F-actin in mushroom toxins.

(S)-ZINC 3573 is a negative control for (R)-ZINC 3573. (S)-ZINC 3573 displays no activity at MRGPRX2 at concentrations below 100 μM.

5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule. It finds applications in DNA synthesis and sequencing.

5-Propargylamino-3'-azidomethyl-dCTP, is a nucleoside molecule. It finds utility in DNA synthesis and DNA sequencing.

Gefitinib impurity 1 is a compound derived from Gefitinib, a potent and selective EGFR tyrosine kinase inhibitor (IC 50 = 33 nM). This orally active compound selectively inhibits tumor cell growth stimulated by EGF (IC 50 = 54 nM) and inhibits EGFR autophosphorylation induced by EGF in tumor cells. Additionally, Gefitinib induces autophagy and exhibits antitumor activity.

7-Methyl-diguanosine triphosphate (m7Gp3G) is a cap analog that integrates into mRNA, playing a crucial role in translation and mRNA degradation within mammalian cells.

Pexopiprant, a potent oral antagonist of the prostaglandin D2 receptor 2 (DP2) with a K i value less than 100nM, is a valuable compound for asthma research.

pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose) polymerase (PARP) enzymes.

PXS-6302 是不可逆的赖氨酸氧化酶 (LOX) 抑制剂，对Bovine LOX、rh LOXL1、rh LOXL2、rh LOXL3、rh LOXL4的IC50分别为 3.7 μM，3.4 μM，0.4 μM，1.5 μM 和0.3 μM。PXS-6302 可以轻松渗透皮肤，减少胶原蛋白沉积和交联，显着改善疤痕外观而不降低组织强度。 PXS-6302 在其他纤维化疾病中也可能有更广泛的应用。

M1 ligand 1 (compound 3b-b) 是槟榔碱衍生物的 N- 去甲基同源物，是毒蕈碱乙酰胆碱受体 M1 的配体。M1 ligand 1 用作正电子发射断层扫描(PET)的放射性示踪剂。

Tyrosinase-IN-1 (compound 90) 是有效的酪氨酸酶抑制剂。酪氨酸酶是一个很前途的靶点，酪氨酸酶抑制剂可用作美白剂和食品防腐剂，因此在食品、化妆品、农业和医药等领域具有广阔的应用前景。

Piperilate, also known as Pipethanate, is a hetrazepine derivative PAF antagonist and anticholinergic mixture, commonly utilized in bronchial asthma research. This compound exhibits hypotensive properties and has been found to effectively counteract the toxic effects of organophosphates in mice [1] [2] [3].

Sovesudil (PHP-201) 是有效的、ATP 竞争性局部作用 Rho 激酶(ROCK)抑制剂。Sovesudil 抑制 ROCK I 和 ROCK II 的IC50分别为 3.7 和 2.3 nM。Sovesudil 可以降低眼压而不引起充血。

Pociredir (FTX-6058) 是一种有效的、选择性的、具有口服活性的胚胎外胚层发育蛋白 (EED) 小分子抑制剂（KD= 0.163 nM）。Pociredir (FTX-6058) 在研究炎症或血红蛋白病中具有研究价值，如镰状细胞病 (SCD)。

PI5P4Ks-IN-1 (compound 7) 是一种与PI5P4Kγ结合的活性化合物。

S1P1 agonist 4 在效价（EC50< 0.05 mg/kg）和预测人类半衰期方面都有更好的表现 （t1/2 ～ 5 天）。

16,17-Dihydroheronamide C 是一种用做 heronamide C 作用模式分析的探针，具有抗真菌作用。

SB-682330A 是一种 Raf 激酶抑制剂。

Fulimetibant 是缓激肽受体 (bradykinin receptor) 拮抗剂。

1-Stearoyl-2-myristoyl-sn-glycero-3-PC 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64546，CAS号为 20664-02-2。

Estrogen receptor antagonist 3 是雌激素受体 (ER) 的有效降解剂。雌激素信号系统在调节细胞生长、分化和凋亡 (apoptosis) 中发挥着重要作用。Estrogen receptor antagonist 4 对癌症疾病表现出研究潜力。

ER degrader 1 是雌激素受体 (ER) 的有效降解剂。雌激素信号系统在调节细胞生长、分化和凋亡 (apoptosis) 中发挥着重要作用。ER degrader 1 对癌症疾病表现出研究潜力。

N-Butylthiophosphoric triamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65336，CAS号为 94317-64-3。

1,2-Diarachidoyl-sn-glycero-3-PC 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67070，CAS号为 61596-53-0。

Fmoc-HoCys(ACM)-OH 是一种氨基酸衍生物，在生命科学相关研究中具有广泛的应用。

Solvent violet 9 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65441，CAS号为 467-63-0。

ELND006 is a novel gamma secretase inhibitor previously under investigation for the oral treatment of Alzheimer's disease. ELND006 shows poor solubility and has moderate to high permeability. The in vivo performance of the ELND006 nanosuspension was tested in fed and fasted beagle dogs and compared with a gelatin capsule containing reference API. The results show that nanosizing ELND006 profoundly improved the oral bioavailability and virtually eliminated variation resulting from food intake.

CFG920 is a CYP17 inhibitor, is also an orally available inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase (CYP17A1 or CYP17), with potential antiandrogen and antineoplastic activities. Upon oral administration, CYP17 inhibitor CFG920 inhibits the enzymatic activity of CYP17A1 in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen-dependent growth signaling and may inhibit cell proliferation of androgen-dependent tumor cells.

CM764 is a potent and selective antagonist of sigma-2 receptors, a novel derivative of SN79.

Galloflavin Potassium is an inhibitor of lactate dehydrogenase.

Cilazaprilat is the active metabolite of cilazapril, a pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.