Antibacterial

Radezolid (RX-1741) 是一种噁唑烷酮类抗生素。它对衣原体，军团菌葡萄球菌，和Linezolid 耐药菌株有活性。

Nifuratel (SAP 113) 是广谱抗生素，有抗细菌、真菌和毛滴虫活性。

Bombinin H5为源自蛾Bombina variegata表皮的抗菌肽。

Vebufloxacin (OPC-7251) shows potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. It has potent activity characteristically against Propionibacterium acnes.

α/β-Hydrolase-IN-1 demonstrates exceptional potency, with MICs of 50 μM (25 μg/mL) against M. smegmatis and 16 μM (8.4 μg/mL) against M. tuberculosis H37Ra, establishing it as a superior compound in this class.

Antifungal agent 6 是抗菌剂。

Nivalenol 是一种由禾谷镰刀菌产生的真菌代谢物。 Nivalenol 通过 caspase 和内在凋亡途径诱导细胞死亡，从而影响免疫系统并引起呕吐、生长迟缓和生殖障碍。

Temafloxacin (hydrochloride) 是一种抗生素和抗分枝杆菌剂。 它用于治疗下呼吸道感染、生殖器和泌尿道感染（如前列腺炎）和皮肤感染。

Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.

Anthrarobin is an antipsoriatic.

Antibiofilm agent-2（化合物 4T）是一种具有3.6 μM IC50的高效生物膜抑制剂。作为针对铜绿假单胞菌的抗菌增效剂，它能够抑制群体感应系统和铁稳态。

Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo.

Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobial effects against Gram-positive bacteria and inhibits both DNA synthesis and DNA gyrase activity, also demonstrating antitumor activity[1][2].

Amdinocillin pivoxil is a Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.

Dicloxacillin Sodium (BRL1702 Sodium) 是一种青霉素类窄谱β内酰胺抗生素, 用于革兰氏阳性菌感染的研究。它对β-内酰胺酶产生的微生物有抗菌作用。

Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。

Gramicidin S（Gramicidin Soviet）是一种阳离子环肽类抗生素，能破坏革兰氏阴性及革兰氏阳性细菌膜的完整性，并抑制细胞色素bd醌醇氧化酶。

Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils.

Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis, which is also the source of platensimycin . Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic resistant bacterial strains, including methicillin-resistant S. aureus, vancomycin-intermediate S. aureus, and vancomycin-resistant Enterococci. For these reasons, platencin has potential applications in fighting antibiotic resistant bacteria.

Brevinin-1E为源自Rana esculenta皮肤分泌物的抗菌肽。

1-(5-Methylfuran-2-yl)ethanone对Mycobacterium tuberculosis具有抑菌活性，可用于生命科学领域的相关研究。

2-Hydroxy-1-methoxyanthraquinone 是一种从 Morinda lucida Benth. (Rubiaceae) 中分离得到具有抗菌活性的天然产物。

10-Hydroxydecanoic Acid (NSC 15139) 是一种存在于蜂王浆中的 10-hydroxy-trans-2-decenoic acid 的饱和脂肪酸，具有抗炎活性。

Tebipenem 是一种口服碳青霉烯类抗生素。 它对革兰氏阳性和阴性细菌具有广谱活性。

Trimethoprim lactate (NSC-106568 lactate) 是一种抗生素，抑制细菌二氢叶酸还原酶 （DHFR）。rimethoprim lactate 具有显示的抗菌活性，对革兰氏菌具有很好的抑制作用。Trimethoprim lactate 单独用于治疗尿路感染，或与其他抗生素联合用于治疗各种眼、肺和胃肠道感染。

Swietemahalactone exhibits antibacterial activity.

Gentamicin C1a，作为半合成抗生素Etimicin的前体，显示出抗菌活性，并且是Gentamicin复合物中的主要成分。

4(3H)-Quinazolinone (4-Hydroxyquinazoline) 是化学合成中的砌块，是一种生物活性氮杂环化合物。它具有多种生物学特性，如抗菌，抗真菌，抗惊厥，抗炎，抗 HIV，抗癌和缓解疼痛活性。

Benzoic acid (Dracylic acid) 是一种存在于许多植物中的芳香醇，是食品，饮料，化妆品和其他产品的常用添加剂。 它作为防腐剂可抑制细菌和真菌。

Broxaldine (Brobenzoxaldine) 是一种具有抗原生动物活性的小分子药物。它抑制艰难梭菌的 MIC 值为 4 µM，并具有抗真菌作用。

Myristoyl glutamic acid sodium，是氨基酸洗面奶的一种抗酸剂，具有轻微的抑菌功能，可清洁皮肤表面多余的油脂和脏污。

Tedizolid Phosphate (TR-701FA) 是 MAO-A 和 MAO-B 抑制剂，具有抗革兰氏阳性菌的活性。

Aconiazide is a prodrug of anti-tuberculosis.