Antibiotic

Alisamycin 是一种手霉素类抗生素 (antibiotic)，对革兰氏阳性菌和真菌具有活性，同时也显示出一定的抗肿瘤活性。

Actamycin 是一种安莎霉素类抗生素 (antibiotic)，具有抗菌活性。

Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory tract infections.

Erythromycin glutamate is a macrolide bacteriostatic antibiotic. This antibiotic is metabolized through the liver and inhibits cytochrome enzyme P450A 3A41.

Epitetracycline is an epimer of the antibiotic tetracycline . Epimers of tetracycline form without catalysis and are considered degradation products. Epitetracycline has decreased activity as an antibiotic or a Tet repressor effector but may have stronger toxic effects in animals.

Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration.

Difloxacin 是第二代合成的氟喹诺酮抗菌抗生素。

Lankacidins is an antitumor antibiotic of the macrolide tetraenes family from Streptomyces.

Ro-23-9424 is a dual-action cephalosporin with a fleroxacin esterified at the 3' position and aminothiazolylmethoxyimino-type side chain at the 7 position. Ro-23-9424 has broad and potent antibacterial activity in vitro and in vivo.

Pirlimycin Hydrochloride, a Clindamycin analog, is a semi-synthetic lincosaminide antibiotic.

Propionylmaridomycin is a macrolide antibiotic.

Epithienamycin E 是碳青霉烯类的成员，Epithienamycin E具有细菌代谢产物的作用。

Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.2

Showdomycin is an antibiotic with antineoplastic activity.

Prumycin is an agent of antifungal antibiotic.

Levofloxacin sodium is a synthetic fluoroquinolones antibacterial. It inhibits the supercoiling activity of bacterial DNA gyrase, so that halting DNA replication.

Diclazuril K is a coccidiostat and GAPDH inhibitor used to prevent parasitic contamination of livestock and poultry feed.

Y 12896 在生命科学相关研究中具有广泛的应用。

Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.

Amoxycillin arginine salt is a bioactive chemical.

Cefroxadine is an orally active cephalosporin antibiotic with a broad spectrum and a bactericidal action. It showed excellent results in the treatment of acute uncomplicated cystitis (AUC).

Levofloxacin mesylate 是一种口服有效的抗生素，抑制革兰氏阳性和阴性细菌。其作用机制为抑制 DNA 促旋酶 (DNA gyrase) 和拓扑异构酶 IV (topoisomerase IV)。Levofloxacin mesylate 适用于慢性牙周炎、气道炎症和 BK 病毒血症的研究，并具有抗正痘活性。

Piperacillin hydrate 是一种半合成广谱 β-内酰胺类抗生素，通过青霉素结合蛋白对革兰阴性菌和某些革兰阳性菌有强杀菌活性。它通常与 β-内酰胺酶抑制剂Tazobactam联合使用。

A 16316-C is a water soluble basic antibiotic, it is isolated from Streptoverticillium eurocidicus.

Exeporfinium chloride(XF-73) is an antimicrobial agent that can weaken bacterial cell walls.

Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.

Dactimicin is a new aminoglycoside. It also has in vitro activity, post-antibiotic effect, and interaction with other antibiotics.

Josamycin HCl is a macrolide antibiotic.

Kalafungin antimicrobial agent that is inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacteria.

Lankacidinol is an antibiotic that has antitumor and immunosuppressive activities.

Lincophenicol is an Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction inhibitor.

Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH.

Tirilazad是一种21-氨基类固醇非糖皮质激素，具有抑制脂质过氧化的能力。它对于脑或脊髓中因创伤、中风、缺血再灌注损伤所致的损害有减轻作用。此外，Tirilazad还展现出针对新型肺炎病毒的抗病毒活性，并在缺血性中风中提供神经保护，适用于蛛网膜下腔出血研究场景。

Sulfisoxazole diethanolamine, also known as Sulfafurazole diethanolamine, is a sulfonamide antibacterial compound with an oxazole substituent. It acts as an endothelin receptor antagonist, specifically targeting endothelin receptor A with an IC50 value of 0.60 μM and endothelin receptor B with an IC50 value of 22 μM. Additionally, Sulfisoxazole diethanolamine has been found to inhibit the release of breast cancer exosomes by specifically targeting endothelin receptor A [1] [2].

Sanfetrinem (GV104326) sodium，作为一种β-内酰胺酶稳定的抗生素(antibiotic)，对革兰氏阳性菌和革兰氏阴性菌展现出广泛的抗菌活性。

Daunorubicin citrate（Daunomycin citrate）作为一种拓扑异构酶 II（topoisomerase II）抑制剂，展现出有效的抗肿瘤活性，通过抑制 DNA 和 RNA 合成（DNA and RNA synthesis）发挥作用。作为一种细胞毒性药物，Daunorubicin citrate 能够抑制癌细胞活性，并诱导细胞凋亡（apoptosis）和坏死（necrosis），属于蒽环类抗生素范畴。该化合物广泛应用于包括白血病、非霍奇金淋巴瘤、尤文氏肉瘤、维尔姆斯氏瘤在内的多种癌症和感染研究领域。