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Amphotericin B methyl ester is the derivative of the antibiotic Amphotericin B. Amphotericin B methyl ester is the cholesterol-binding compound that possesses significant antifungal activity. It disrupts HIV-1 particle production and potently inhibits HIV

CMLD012073 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits NIH/3T3 cells (IC50: 10 nM). CMLD012073 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A).

Erythromycylamine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64443，CAS号为 26116-56-3。

KL001 是一流的隐花色素蛋白 (CRY)稳定剂，可与 CRY1 和 CRY2 特异性相互作用。其中CRY 是一种对蓝光敏感的黄素蛋白，参与调节动植物的昼夜节律。KL001能够防止泛素依赖性 CRY 降解，从而延长了昼夜节律周期，具有控制空腹激素诱导的糖异生的潜力。

CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50= 0.06 μM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 μM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50= ~100 nM). 1.Cole, A.G., Stroke, I.L., Brescia, M.-R., et al.Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonistsBioorg. Med. Chem. Lett.16(1)200-203(2006)

Topiramate lithium (McN 4853) is a wide-ranging antiepileptic compound with GluR5 receptor antagonistic properties. Its mechanism of action involves enhancing GABAergic activity, inhibiting kainate/AMPA receptors, voltage-sensitive sodium and calcium channels, and increasing potassium conductance. Additionally, this compound inhibits carbonic anhydrase. [1][2][3]

Anserine (Standard) 是一种可用于分析的标准物质，通常用作 Anserine 的研究和分析中参考的标准样品。Anserine (L-Anserine) 是 Carnosine 的甲基化形式，是口服具有活性的天然二肽，存在于脊椎动物的骨骼肌。它不会被血清肌肽酶裂解，能够作为生化缓冲液，螯合剂，抗糖化剂和抗氧化剂。它能够改善阿尔茨海默氏病模型小鼠的记忆功能。

Tauro-α-muricholic Acid (sodium salt) (Standard) 是一种可用于分析的标准物质，通常用作 Tauro-α-muricholic Acid (sodium salt) 的研究和分析中参考的标准样品。Tauro-α-muricholic acid (TαMCA) 是法尼醇 X 受体（FXR）的拮抗剂（其半数抑制浓度为 28 微摩尔），并且是鼠类特有的α-麦鲁基酸的牛磺酸结合形式。塔罗-α-麦鲁基酸在啮齿动物体内较为常见，但在人类血清中也有少量存在。

Antiviral agent 14 是一种抗病毒剂，能够抑制烟草花叶病毒 (TMV) (EC50: 135.5 μg/mL)，和黄瓜花叶病毒 (CMV) (EC50: 178.6 μg/mL)。

L-693612 HCl is an inhibitor of carbonic anhydrase.

4,4'-Methylenediphenol 首次从 Galeola Faberi 的根茎中分离出来，具有抗氧化活性。

Integrase-LEDGF/p75 allosteric inhibitor 1 是一种口服具有活力的 integrase-LEDGF/p75 (IN-LEDGF/p75) 变构抑制剂。Integrase-LEDGF/p75 allosteric inhibitor 1 能够抑制 HIV-1 DNA 整合，表现出抗病毒作用，能够作用于 HIV-1重组分子克隆 NL432 (EC50: 3.9 nM)。

EGFR-IN-56 (Compound 13a) 是一种 EGFR 的有效抑制剂，能够作用于 EGFRT790M (IC50: 541.7 nM) 和 EGFRT790M/L858R (IC50: 132.1 nM)。EGFR-IN-56 能够将癌细胞的细胞周期阻滞在 G2/M 期，并诱导细胞凋亡 (apoptosis)。

2-Nitropropane是一种有机硝基化合物，在工业上用作油墨、油漆、粘合剂、清漆、聚合物、树脂、燃料和涂料配方中的溶剂或性能添加剂。2-Nitropropane 也用作合成其他工业化学品的化学原料，并且是合成苯丁胺、氯苯丁胺和替克洛赞等药物的关键反应物，此外它还作为氧化剂参与 Hass–Bender 氧化化学过程。

4-Hydroxyphenyl Carvedilol, a metabolite of Carvedilol, is associated with the pharmacological activity of this beta-blocker/alpha-1 blocker.

369-Trioxaundecanedioic Acid, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].

DprE1-IN-1 是一种有效的、口服具有活力的 DprE1 抑制剂，表现出良好的肝细胞稳定性、低细胞毒性和低 hERG 通道抑制。DprE1-IN-1 能够有效抗 DprE1-IN-1 对药敏和临床分离的耐药结核菌株 (MICs<0.1 μg/mL)。DprE1-IN-1 在巨噬细胞内具有良好的抗分支杆菌活性，能减少 1.29 log10 CFU。

Foliglurax monohydrochloride Antiparkinsonian effect. is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM.

Bromo-PEG3-phosphonic acid diethyl ester is a polyethylene glycol (PEG) derivative commonly employed as a linker for the assembly of proteolysis targeting chimeras (PROTACs)[1].

Bio-AMS为一种选择性针对结核分枝杆菌（Mtb）有效的细菌生物素蛋白连接酶抑制剂，同时可抑制脂肪酸及脂类的生物合成。

C8 Dihydroceramide acts as a negative control for C8 Ceramide, a cell-permeable analog of natural ceramides. C8 Ceramide, also known as N-Octanoyl-D-erythro-sphingosine, exhibits potent chemotherapeutic properties and anti-proliferation effects. Additionally, it stimulates dendritic cells to enhance T cell responses during viral infections. In vitro studies have also shown that C8 Ceramide induces a slight activation of protein kinase (PKC) [4].

AKT-IN-7 (compound 1-P1) 是一种 AKT 的有效抑制剂。AKT-IN-7 具有潜力进行癌症的研究。

Amoxycillin arginine salt is a bioactive chemical.

Propargyl-PEG8-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hetrombopag 是一种 thrombopoietin receptor 的有效激动剂。Hetrombopag 具有良好的耐受性且安全性可控。Hetrombopag 具有潜力进行免疫性血小板减少症的研究。

Salcomine (NSC-32965) 具有抗流感病毒活性。

c-Met-IN-13 是 c-Met 的有效抑制剂 (IC50: 2.43 nM)。c-Met-IN-13 以浓度依赖性及时间依赖性方式表现出抗增殖作用。c-Met-IN-13 对癌细胞表现出显著的细胞毒性。c-Met-IN-13 对癌症表现出治疗潜力。

Aβ42-IN-1，化合物 1v，是一种新型有效且具有口服活性的 γ 分泌酶调节剂 (GSM)。 Aβ42-IN-1 在不抑制 CYP3A4 的情况下，在培养细胞中有效降低Aβ42水平，IC50值为 0.091 μM。Aβ42-IN-1 显示出良好的药代动力学特征。

Trt-PEG4-C2-acid (hydrate) is a polyethylene glycol (PEG)-derived linking moiety, specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs).

Hydroxy-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.

2,6-TRI-O-METHYL-1,3:5,7-DI-O-METHYLENE-D-GLYCERO-D-GALACTO-HEPTITOL 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64935，CAS号为 5965-83-3。

CGS 21680 是一种选择性的腺苷和腺苷 A2A 受体激动剂，Ki 值为 27 nM。

WWL113 is a selective and orally active Ces3 and Ces1f inhibitor (IC50: 120 nM and 100 nM for Ces3 and Ces1f, respectively). WWL113 appears to display excellent selectivity for the 60-kDa serine hydrolase.

SB-747651A is a potent, ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1, IC50 = 11 nM). It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells.

Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.