Others

N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1657，CAS号为 2382942-32-5。

Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective agonist for dopamine autoreceptors with potential applications in schizophrenia research [1] [2].

AR-13503, is an metabolite of Netarsudil (AR-11324), is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and​/or reducing intraocular pressure.

STINGagonist-25 (CF505) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING，增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。

CysLT1 leukotriene receptor antagonist

Ibuprofen alcohol, a nonsteroidal antiinflammatory drug (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs).

TK4b 可用于淋巴源性疾病和白血病癌症的研究。TK4b 是一种Janus 激酶(JAK) 抑制剂，其对 JAK3 和 JAK2 的IC50值分别为 18.42 nM 和19.40 nM。

Methyltetrazine-PEG12-DBCO is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

(R)-Eucomol，一种类黄酮衍生物，展现出微弱抗菌活性，并对KB和P-388细胞表现出细胞毒性。

d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.

AG1478 HCl is an epidermal growth factor receptor protein inhibitor.

3-Acetamidocoumarin, a compound significant in biology and medicine, exhibits physiological effects and is utilized in treating various conditions, including burns, brucellosis-rheumatic diseases, and cancer.

L-869298 is a potent and selective inhibitor of PDE4.

ZSET-845 is an enhancer of cognitive which enhances choline acetyltransferase activity in the hippocampus in the rat.

TYK2-IN-12 (compound 30) 是一种选择性的、口服具有活力的 TYK2 (酪氨酸激酶 2) 抑制剂 (Ki: 0.51 nM)。TYK2-IN-12 对 IL-12 诱导的人和小鼠全血中 IFNγ 具有抑制作用，他们的 IC50 值分别为 2.7 和 7.0 μM。TYK2-IN-12 能够用于研究银屑病。

HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.

Mal-C6-amine (TFA) is an alkyl chain-based linker employed in the synthesis of PROTACs[1].

7-Hydroxy-4-methylcoumarin-3-acetic acid（7-羟基-4-甲基香豆素-3-乙酸）是一种蓝色荧光团，具有pH依赖性和环境敏感性荧光，广泛用于标记肽、核苷酸和碳水化合物，还可用作pH值指示剂。

SAH (Standard) 是一种可用于分析的标准物质，通常用作 SAH 的研究和分析中参考的标准样品。SAH (S-Adenosylhomocysteine) 属于氨基酸衍生物，是腺苷和半胱氨酸合成的中间体。SAH 是一种 METTL3-METTL14 异二聚体复合物的抑制剂 (IC50=0.9 µM)。SAH 是多种代谢途径中的调节剂。

Adriforant hydrochloride is an antagonist of histamine H4 receptor.

Lobenzarit, an immunomodulator, is most frequently used to treat arthritis. Its chemical scaffold has been repurposed to tryptophan biosynthesis in Mycobacterium tuberculosis

Chymase-IN-1 是一个有效的，有选择性的，口服有活性的人肥大细胞糜蛋白酶抑制剂，IC50 为 29 nM。

Rolusafine 是一种抗真菌剂。

1-Deazaadenosine is a potent Adenosine deaminase inhibitor (Ki: 0.66 μM). It exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders.

Binifibrate is a hyperlipemiant drug used for the treatment of hyperlipidemia.

SKF1 is a suppressor of the ability of FK506. SKF1 inhibits cell growth in the presence of high levels of NaCl, induces cell death in low salt conditions, interacts directly with yeast mitochodria.

C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai

AP5 sodium 是选择性的、有效的、口服具有活力的 GPR40 受体激动剂，对内源性配体 (AgoPAM) 表现出正向变构调节效果。AP5 sodium 在大鼠和人肌醇一磷酸 (IP1) 实验中作用于 GPR40 受体，他们的 EC50值分别为 0.49 nM 和 0.8 nM。AP5 sodium 表现出研究 II 型糖尿病的潜能。

MY-1B 是一种氮杂替丁丙烯酰胺立体探针，可阻断对 NSUN2 的立体选择性富集，选择性地结合 NSUN2 的 C271。

Ms-PEG2-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Diethylamiodarone is the main metabolite of amiodarone in vivo.

Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.2

Antimalarial agent 15 是 parasite 抑制剂，表现出抗疟作用，对恶性疟原虫 3D7 的生长具有抑制作用，其 IC50值为20 nM。

SOS1-IN-13 是有效的SOS1抑制剂。SOS1-IN-13抑制 SOS1 和 pERK 的IC50分别为 6.5 nM 和 327 nM。SOS1-IN-13 在抗癌研究中具有一定的价值。