Others

TDP1 Inhibitor-1 is a potent inhibitor of Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (IC50 of 7 μM).

Alimemazine (Trimeprazine) is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Alimemazine also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs.

Dual 5-HT1B/1D receptor antagonist

AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.

Glucagon receptor antagonist -1 is a highly effective glucagon receptor antagonist.

CE3F4 analog 1 is an analogue of CE3F4.

4-MUNANA(4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid sodium salt) 是用于神经氨酸酶 (neuraminidase) 活性测定的荧光底物，是神经氨酸酶底物类似物。

Levamisole是一种片段化合物。

Minimolide F 是从 Centipeda minima 中分离得到的，对人鼻咽癌细胞具有抗增殖活性，IC50 为 17.4 μM。

Podecdysone B 是一种从露水草中分离出来的植物蜕皮激素。

α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate) 是植物细胞壁果胶多糖鼠李糖半乳糖醛酸聚糖 1 、鼠李糖半乳糖醛酸聚糖 2 的组分。它也是细菌多糖的组分之一，在致病性方面起重要作用。

ζ-Stat trisodium (NSC37044 trisodium) is a potent and selective inhibitor of protein kinase C-ζ (PKC-ζ), exhibiting an IC50 of 5 μM. It effectively suppresses the proliferation of melanoma cell lines and promotes apoptosis. Moreover, ζ-Stat trisodium demonstrates notable antitumor activity in vitro.

L-ascorbic acid 2-phosphate（维生素C磷酸酯）是一种稳定而长效的维生素C衍生物，能够刺激胶原蛋白的形成且具有潜在的抗氧化能力。通过提高碱性磷酸酶（ALP）活性和runx2A的表达，L-抗坏血酸-2-磷酸酯在细胞培养中常用于促进人脂肪干细胞（hASCs）的成骨分化。

Gamma-Glutamylarginine是一种天然的γ-谷氨酸寡肽，是由谷氨酸和精氨酸组成的二肽。

Pomonic酸，作为一种三萜化合物，能显著抑制胆固醇酯的积累，并降低酰基辅酶A：胆固醇酰基转移酶（ACAT）的活性。

2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.

Azide-PEG7-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

PXYC2 是一种核糖体蛋白 S1 (RpsA) 拮抗剂，对 RpsA-CTD 和 RpsA-CTD Δ438A 的 Kd 分别为 6.35 和 5.11 μM。在结核分枝杆菌 (Mtb)转译过程中，RpsA 发挥重要作用。

1,3-dihydroxy-4-methoxy-10-methylacridin-9-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2491，CAS号为 1189362-86-4。

N-tert-Butylisopropylamine是一种仲胺，广泛应用于生物化学实验和药物合成研究。

Mal-NH-PEG2-CH2CH2COOPFP ester is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

BTI-A-404 is a potent and selective competitive inverse agonist of human GPR43.

MitoTam iodide, hydriodide is an inhibitor of electron transport chain (ETC)

ERβ receptor agonist

κ receptor antagonist

Kelatorphan is an enkephalin degrading enzyme full inhibitor.

Sebetralstat (KVD900) 是一种血浆激肽释放酶抑制剂，可用于代谢性疾病的研究。

Methyl 2-(1H-indol-3-yl)acetate (Standard) 是一种可用于分析的标准物质，通常用作 Methyl 2-(1H-indol-3-yl)acetate 的研究和分析中参考的标准样品。苹果中含有 Methyl 2-(1H-indol-3-yl)acetate。它是从海豌豆(Lathyrus maritimus)、紫豆(Vicia amurensis)、野生大豆(Glycine soja)、野豆(Vigna catiang var. sinensis)和风信子豆(Dolichos lablab)的未成熟种子中分离得到的。Methyl 2-(1H-indol-3-yl)acetate 具有抗肿瘤活性。

GABAA receptor inverse agonist

4-(10,15,20-Triphenyl-21H,23H-porphin-5-yl)benzenamine是一种卟啉衍生物，主要用于光化学和材料科学研究。

3-(5-Methylfuran-2-yl)propanoic acid是一种合成的非蛋白源性氨基酸，其特征是具有标准的三碳丙酸骨架，α碳（C2）处有一个氨基官能团（-NH2），β碳（C3）处有一个独特的5-甲基呋喃-2-基取代基。其中呋喃环——一个含氧原子的五元芳香杂环,提供了其独特的结构和电子特性。

PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.

2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside.

Pomalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that combines the cereblon ligand based on Pomalidomide with a linker. This compound is instrumental in designing PROTAC BRD4 Degrader-1[1].

BRD9092 是一种小分子探针，可升高氧化应激标志物而不会导致细胞死亡。

PI3K-IN-35 (Compound 6l) 是一种 PI3K 的高选择性抑制剂，作用于 PI3K-α (IC50: 13.98 μM)、PI3K-β (IC50: 7.22 μM) 和 PI3K-δ (IC50: 10.94 μM)。PI3K-IN-35 可将细胞周期阻滞于 G2/M 期，并诱导细胞凋亡。PI3K-IN-35 能够用于研究白血病。