Antifection

Cuniloside B shows anti-leishmanial activity.

Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana.

Drimenol shows antifungal activity, it is able to affect Botrytis cinerea growth with the EC50 value of 80 ppm. Drimendiol also shows quorum sensing inhibition activity.

Isoboonein exhibits significant antitumor and antibacterial activity.

3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside exhibits in vitro antiplasmodial activity.

2-Methoxy-1H-phenalen-1-one (2-Methoxyphenalen-1-one) displays significantly enhanced activity against Mycosphaerella fijiensis in comparison with other phenylphenalenones.

Citromycin, an antibiotic, has weakly cytotoxic.

Kaempferol-3-O-α±-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging ROS, and protect cellular membrane against ROS; they can be applicable to new cosmeceuticals for antioxidant, antiaging, and antibacterial activity.

Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM).

Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mice.

(+)-Goniodiol and 7-epi-(+)-Goniodiol show high antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia.

2α,3α,24-Trihydroxyolean-12-en-28-oic acid, a triterpenoid phytoalexin, isolated from peel of unripe fruits of nectarine (Prunus persica cv Fantasia), shows antifungal activity against the fungus mentioned.

L-I-OddU, a potent and selective anti-Epstein-Barr virus (EBV) agent, is a L-5'-halo-dioxolane nucleoside analogue. It demonstrates antiviral activity by effectively suppressing replicative EBV DNA and viral protein synthesis [1] [2]. With an EC 50 value of 0.03 μM, L-I-OddU exhibits high potency against EBV while maintaining low cytotoxicity, as indicated by its CC 50 value of 1000 nM.

Macrocarpal H has anti-glucosyltransferase, and anti-bacterial activities.

Cerbinal 是一种天然化合物，来源于非洲非洲菊的草本植物。它具有杀虫活性，是一种潜在的新型害虫防治剂。

Lobucavir (BMS-180194; SQ 34514)为一种抗病毒核苷类似物，其具备广谱活性，效力涵盖HBV、HIV/AIDS以及各类型疱疹病毒（α、β、γ），包括CMV、单纯疱疹病毒、水痘带状疱疹病毒及Epstein-Barr病毒。

Methyl lucidenate L 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5980，CAS号为 110267-46-4。

Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.

14-O-Acetylindolactam V 能够诱导早期 Epstein-Barr 病毒抗原的表达。

Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL.

2,3-Dihydrohinokiflavone 是基质金属蛋白酶 (MMP) 基因表达的抑制剂，对利什曼原虫具有很强的活性，IC50 为 1.6 μM。

Altenuene 是一种霉菌毒素，经常出现在被链格孢属真菌侵染的食物和饲料中。 Altenuene 表现出对金黄色葡萄球菌的中等活性。 Altenuene 还表现出对肺癌细胞系 A549、乳腺癌细胞系 MDA-MB-231 和胰腺癌细胞系 PANC-1 的细胞毒活性。

Econazole ((±)-Econazol) 是一种咪唑衍生物，是一种抗真菌剂。

1(10)-Aristolen-2-one has antifungal activity.

Garcinone C 是一种从 Garcinia oblongifolia Champ 中提取的黄酮衍生物，具有抗炎、收敛和促进肉芽的活性。 Garcinone C 是一种 AChE 抑制剂，对某些癌症具有潜在的细胞毒性作用。

Chlorhexidine diacetate (Bactigras) 是一种双胍类杀菌剂，能快速消灭革兰氏阳性菌和革兰氏阴性菌。它也用作漱口水以防止口腔菌斑。

Vitexolide D shows moderate antibacterial activity against a panel of 46 Gram-positive strains. It also shows cytotoxic activities against the HCT-116 cancer cell line and human fetal lung fibroblast MRC5 cell line (1 < IC50s < 10 uM).

Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.

Homaloside D has antiplasmodial activity.

Narcissin (Isorhamnetin 3-Rutinoside) 是一种黄连糖苷，能够清除 ONOO-(IC50:3.5 μM)和 SIN-1 衍生的 ONOO-(IC50:9.6 μM)，具有抗氧化作用。

Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro.

NIBR189是 EBI2（GPR183）小分子拮抗剂(IC50:11 nM)。

Ganciclovir (2'-Nor-2'-deoxyguanosine) 是核苷类似物和口服抗病毒药物，对CMV 具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。

Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans.

Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladd

VK-1727 是一种选择性的小分子 EBNA1 抑制剂，可降低 EBNA1 的 DNA 结合活性，同时限制 EBV 阳性细胞的增殖和代谢活性，而不影响 EBV 阴性细胞的存活。VK-1727 主要应用于多发性硬化症相关研究，作为工具化合物用于探索 EBNA1 介导的疾病相关机制。